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Transplantation DIRECT Journal OCtober Issue

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The October issue of Transplantation Direct delivers a variety of articles to peak your interest. In kidney transplantation, a number of issues related to organ suitability are investigated, including analyses of donor/recipient size matching, and the influence of donor age in cases of donation after circulatory death. A literature-based review of living kidney donor evaluation efficiency reveals promising opportunities to improve this process. Adherence to long-term immunosuppression and its relationship to kidney transplant histology are explored in detail. Predictive renal function tests for increased risk of cardiovascular events in kidney transplant recipients are investigated, and another article focuses on a predictive model for detecting hyperglycemia in nondiabetic recipients after liver transplantation. A first report on using hypothermic oxygenated machine perfusion to improve the quality of human pancreas grafts is also featured in this issue. In addition, we include publication of the 2018 islet and pancreas transplant report from the Australian and New Zealand group. Enjoy these and other aspects of the October Transplantation Direct issue!.

LINK TO THE ISSUE (OPEN ACCESS)

ISN-TTS SISTER TRANSPLANT CENTERS PROGRAM - Deadline Extended to tomorrow October 5

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The EXTENDED deadline to submit an application to the ISN - TTS Sister Transplant Centers Program is October 5, 2018 (for 2019).

The ISN-TTS Sister Transplant Centers Program is a joint partnership set up between ISN and The Transplantation Society (TTS) to create new kidney transplant centers and develop existing kidney transplant programs in emerging countries. This initiative encourages transplant centers to work together to increase opportunities for kidney transplant patients in developing countries.

Read more on th program and get some useful tips

Over 500 Signups TO DATE!
Registration Closes TuesdAY OCTober 9 at 23:59

TTS-STALyC ONLINE INTERACTIVE UPDATE COURSE
IMMUNOLOGICAL ASPECTS IN SOLID ORGAN TRANSPLANTATION

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From October 3 to November 27

Over an eight week period, featuring 28 online presentations, we will guide your through all the important aspects in immunology. We have enlisted many expert tutors to accompany the participants in the discussion by replying to questions throughout the week. The course was designed to allow participants to learn at their own pace and time during each week of the course.

The course has two sets of pricing (regular and for students/residents):

  • Regular fees are $100 USD, $40 USD for TTS or STALyC Members; $20 if you are a member of both TTS and STALyC.
  • Students/Residents can register for $40, $20 for TTS or STALyC Members, free for TTS AND STALyC Members.
  • We will allow registration at the reduced member fees if you submit your application(s) prior to registering for the course.

Share this information with your fellows, post-docs and students!

FOR MORE INFORMATION, PLEASE VISIT WWW.TTS-STALYC.ORG

TRANSPLANTATION JOURNAL - HIGHLIGHTED ARTICLE

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Dr Karen Keung, Editorial Fellow, Transplantation.

Long-term Outcomes of Pediatric En-Bloc Compared to Living Donor Kidney Transplantation: A Single-Center Experience With 25 Years Follow-Up.
Sureshkumar KK, Habbach A, Tang A, Chopra B.
Transplantation. 2018;102:e245-e248.

Pediatric en-bloc kidneys are not accepted by all centers for the transplantation into adults. There is limited data on extended long-term outcomes of these allografts. In a previous study, the authors had retrospectively compared the outcomes of pediatric en-bloc versus living donor kidney transplantation into adults at their center and identified inferior 1 year graft survival, but comparable 5-year graft survival and improved function up to 8 years following transplantation in en-bloc kidney recipients. In this retrospective review, the authors report on long-term outcomes of this cohort.
72 pediatric en-bloc and 75 living donor kidney transplants were transplanted between 1990 and 2001; immunosuppression was similar in both groups and included cyclosporine, azathioprine and prednisone prior to 1996 and cyclosporine, mycophenolate mofetil and prednisone for transplants between 1996 and 2001. Pediatric donors were 16.9 ± 11.2 months old and weighed 10.7 ± 3.8 kg with terminal serum creatinine of 0.50 ± 0.45 mg/dL. Living donors were 40.1 ± 9.4 years old and serum creatinine was 0.90 ± 0.16 mg/dL at the time of donation. Delayed graft function was more frequent in pediatric en-bloc kidneys (26.4% vs 6.7%, P = 0.001). Kaplan-Meier estimate revealed similar graft survival between the groups up to 27 years of follow up (log rank P = 0.78). Estimated glomerular filtration rates were consistently higher in pediatric en bloc kidney recipients from years 5 through 17 posttransplantation.
The study demonstrated that pediatric en-bloc kidneys confer long-term graft survival rates comparable to living donor kidneys and along with superior graft function, supporting the utilization of these allografts which may help alleviate the waiting list burden.

CLICK TO READ THIS OPEN ACCESS ARTICLE

Save tHe Dates!

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Young Members Committee

The Young Members Committee is seeking active TTS members from Asia-Pac, Middle East, Africa and Latin America who want to take an active role in representing their regions.

Email This email address is being protected from spambots. You need JavaScript enabled to view it. if you are interested!

A reporter wrote an article on the illicit trade in human organs. Now people from all over the world email me trying to sell their kidneys

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October 1 - As a foreign correspondent, I was accustomed to seeking out people in difficult circumstances. Now they were seeking me out, showing up in my email at all hours — when I was writing another story, racing to catch a flight, having dinner with my wife at home in Mumbai or trying to rock one of our newborn twins to sleep — and becoming impossible to ignore..

CLICK HERE To read more

In the News

Chung-Ang University Hospital succeeds in 3D-printing chest transplant

Professor Park Byung-joon and his team at Chung-Ang University Hospital’s Department of Thoracic and Cardiovascular Surgery announced on Thursday the successful surgery results of transplanting a 3D-printed ribcage to a patient with sarcoma, a malignant tumor that invaded the thorax.

READ THE FULL ARTICLE


Chronic allograft injury common among pediatric liver transplant recipients

September 28 - A substantial proportion of pediatric liver transplant patients with normal liver tests have varying degrees of subclinical chronic allograft injury, according to new findings. For the study, Dr. Sandy Feng of University of California, San Francisco, and her colleagues used data collected for iWITH, an immunosuppression-withdrawal trial that included 157 stable long-term recipients of liver transplants from living or deceased donors (45% boys).

READ THE FULL ARTICLE


COPD in patients after heart transplantation is associated with a prolonged hospital stay, early posttransplant atrial fibrillation, and impaired posttransplant survival

September 27 - COPD is associated with reduced physical activity, an increased risk for pulmonary infections, and impaired survival in nontransplant patients. The aim of this study was to investigate the influence of COPD in patients after heart transplantation (HTX).

READ THE FULL ARTICLE


Kidney Transplant Success Improved by Swedish Biotech’s Drug

There is hope for many patients on the kidney transplant waiting list, as a Swedish biotech’s lead candidate drug could help reduce rejections in kidney transplant patients.

READ THE FULL ARTICLE


Clear up this stem-cell mess

September 26 - Confusion about mesenchymal stem cells is making it easier for people to sell unproven treatments, warn Douglas Sipp, Pamela G. Robey and Leigh Turner.

READ THE FULL ARTICLE


HIV positive mom's liver transplanted into HIV negative child

October 4 - Johannesburg- In what is believed to be the first in the world, researchers at Wits University have transplanted a liver from an HIV positive mother to her HIV negative child.

LINK TO THE ARTICLE


Would you rather die of liver failure or live with HIV?

October 4 - This was the ethical dilemma faced by doctors at Wits Donald Gordon Medical Centre to save a child's life.

LINK TO THE ARTICLE


Heart transplant outcome linked to gut bacteria, study finds

October 4 - Gut bacteria appears to play a key role in whether a body accepts a transplanted heart, according to a new study. The study found bacteria appears to play a key role in the whether a body accepts a transplanted heart. The overall survival rate in the United States of heart transplants is about 88 percent after one year and about 75 percent after five years

READ THE FULL ARTICLE

IPTA 2019 - Call for Abstracts Now Open

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THE ORGANIZERS OF THE 10TH CONGRESS OF THE INTERNATIONAL PEDIATRIC TRANSPLANT ASSOCIATION WELCOME YOU TO SUBMIT AN ABSTRACT. THE SUBMISSION DEADLINE IS NOVEMBER 5, 2018.

call for abstracts large

CLICK HERE FOR MORE DETAILS


Upcoming Meetings

CTRMS SPECIAL WORKSHOP

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Full program is now available on THEIR website!

VISIT THE WORKSHOP WEBSITE

IPTA 2018 Symposium

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The International Pediatric Transplant Association is proud to feature a special section activity: the 2018 Symposium in Organ Transplantation in Children: An educational forum for physicians, surgeons, and allied health professionals.

The focus of this symposium is aimed at clinical and research fellows in pediatric solid organ transplantation, as well as residents, and other allied health professional or non-physician trainees who are planning a career in pediatric transplantation.

VISIT THE SYMPOSIUM WEBSITE

Official Sections of The Transplantation Society

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