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Reproductive Bioengineering

0.0 - Reproductive Bioengineering: From Fertility Therapies to Digital Pregnancy

Presenter: Christian Kramme, Kristin Myers, , , Unites States
Authors: Christian Kramme, Kristin Myers, David Lott, Rohan Paul, Alice Tomei

Overview

Dr. Kramme will discuss Advancements in the use of human induced pluripotent stem cell-derived therapies for infertility treatment: Fertilo In Vitro Maturation.

Description

Dr. Myers will discuss Digital Twins of Pregnancy: A New Approach to Predicting Preterm Birth

Description

Learning Objectives

  • Translation and development of induced pluripotent stem cell derived therapies for clinical use as biologics including manufacturing, toxicology, and clinical studies. (Dr. Kramme)
  • The field of in vitro fertilization and in vitro maturation including challenges, unique opportunities, and patient impact. (Dr. Kramme)
  • Future directions of ex vivo and in vivo iPSC-derived cell therapies for use in women's health and infertility. (Dr. Kramme)
  • Describe the biomechanical changes that occur in the uterus, cervix, and fetal membranes during a healthy pregnancy, including how progressive cervical softening prepares the body for delivery. (Dr. Myers)
  • Explain how computational "digital twin" models integrate ultrasound imaging and cervical stiffness measurements to characterize the mechanical environment of individual pregnancies. (Dr. Myers)
  • Identify how comparing biomechanical profiles between low- and high-risk patients may help clinicians recognize early physical warning signs of preterm birth and inform future risk-prediction tools. (Dr. Myers)

Supporting Material

CTRMS President-Elect
Alice Tomei, USA
Moderator
Bio
David Lott, USA
Moderator
Bio
Rohan Paul, USA
Moderator
Bio
Christian Kramme, USA
Speaker
Bio
Kristin Myers, USA
Speaker
Bio

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