In The News - Volume 1 - Issue 11 - June 3, 2015

New discoveries advance efforts to build replacement kidneys in the lab
June 1, 2015 - Researchers at Wake Forest Baptist Medical Center report progress in their quest to build replacement kidneys in the lab. The teams' goal is to make use of the more than 2,600 kidneys that are donated each year, but must be discarded due to abnormalities and other factors. The scientists aim to "recycle" these organs to engineer tailor-made replacement kidneys for patients. [more]

MGH researchers develop bioartificial replacement limbs suitable for transplantation
June 3 - A team of Massachusetts General Hospital (MGH) investigators has made the first steps towards development of bioartificial replacement limbs suitable for transplantation. In their report, which has been published online in the journal Biomaterials, the researchers describe using an experimental approach previously used to build bioartificial organs to engineer rat forelimbs with functioning vascular and muscle tissue. They also provided evidence that the same approach could be applied to the limbs of primates. [more]

Fabrication of three-dimensional bioplotted hydrogel scaffolds for islets of Langerhans transplantation
May 27 - Researchers have explored how 3D printing can be used to help treat type 1 diabetes. The 3D printing technique, known as bioplotting, has taken researchers one step closer to being able to help patients who experience severe hypoglycaemic events, commonly known as 'hypos'- a problem that affects about a third of people with type 1 diabetes. [more]

ASU researchers taking bold steps toward engineering new lungs
May 26 - The new study, jointly funded by NIH, NASA, and a Mayo Clinic-ASU seed grant, demonstrates a number of critical advantages to conducting the cell re-population process in a dynamic suspension culture, in which the cells are allowed to gently tumble as they re-seed the decellularized lung. [more]

Portable device measures donor liver function, predicts organ survival
June 1 - In a new study conducted by researchers at University of California at Los Angeles, a portable, finger-probe device was successful in measuring liver function in brain dead adult organ donors, according to newly published data. [more]

Stem cell technology could lead to ailing heart mending itself
May 28 - For the first time, scientists can efficiently generate large numbers of rare cells in the network that pushes the heart's chambers to consistently contract. The technique, published May 28 in Stem Cell Reports, could be a first step toward using a person's own cells to repair an irregular heartbeat known as cardiac arrhythmia. [more]

European researchers developing implantable, insulin-controlling capsule to fight diabetes
May 26 - Irish researchers have developed a gel containing clusters of pancreatic cells that they say can control glucose levels for up to 5 years . [more]