Transplantation Journal - July 2026
Visceral Adipose Tissue and its crosstalk with the liver allograft: implications for transplant outcomes
Researcher from Spain and Switzerland present in this timely and exciting review emerging molecular and cellular mechanisms underlying the crosstalk between visceral adipose tissue, the liver allograft, and alloimmunity. Those aspects are of clear clinical relevance when utilizing extended criteria donor grafts and when transplanting livers into recipients with MASLD, HCC, or cirrhosis. Therapeutic strategies aimed at reprogramming adipose tissue toward a less inflammatory, more tolerogenic state are highlighted.
Oxygenated perfusion enhances hepatocyte function in human iPSC-liver tissue
Authors from Japan developed a novel method to generate functional and transplantable liver tissue using human induced pluripotent stem cell derived liver organoids.
By infusing those organoids into decellularized liver scaffolds and applying an oxygenation system based on hemoglobin vesicles, researchers successfully created liver tissue with enhanced engraftment and hepatic function. Their data demonstrate that oxygenated human induced pluripotent stem cell liver tissue produces liver specific proteins and relevant metabolic genes. Moreover, transplantation of these tissues onto the liver surface of immunodeficient mice improved functional integration.
Direct Measurement of Organ Procurement Organization Donor Potential using Comprehensive Referral Analysis: Feasibility and Implications for Assessing OPO Performance
Previous approaches for assessing Organ Procurement Centers have not been reliable. Here, authors suggest using validated referral data to assess donor potential. The authors assessed hospital records of > than 45.000 potential organ donors and evaluated reasons why donations did not proceed. This approach was possible by using robust electronic systems in each OPO. The authors show that this method has the potential to provide more accurate data than previously provided through administrative data sources. National organizations may use this approach to refine quality assessments.
Impact of high-emergency lung transplantation procedure on 1-year survival in France
Using data from all 10 French Lung Transplant Centers, the authors selected > than 900 patients who underwent high emergency lung transplantation. Survival did not differ over 1 year when compared to standard lung transplants. Moreover, a multivariable analysis showed that high-emergency transplantation was neither associated with an increased risk of 1-year mortality nor with an augmented postoperative morbidity. Those data respond to previous concerns that high emergency lung transplantation is associated with worse prognosis.
Latest Behind the Papers Podcasts
Episode 24: Behind the Paper: Sex Disparities in Transplantation Access and Outcomes | Bethany Foster, MD
In this Behind the Paper episode, Macey Levan, Social Media Editor for the Transplantation journals, interviews Bethany Foster, MD, a pediatric nephrologist and professor at McGill University, about the key insights from:
📄 Sex Disparities in Transplantation Access and Outcomes: An Overview
Review Article
Published in Transplantation — April 2026
This review explores how sex disparities affect access to and outcomes after solid organ transplantation, including kidney, heart, liver, and lung transplantation. The conversation examines the barriers women may face throughout the transplant journey, from referral and waitlisting to transplantation and post-transplant outcomes.
The episode highlights:
- How women may experience reduced access to transplant evaluation, waitlisting, and transplantation
- Why sex disparities appear more pronounced in older age groups
- How unconscious or conscious bias may influence clinical decision-making
- The role of perceived frailty, obesity, and risk assessment in transplant access
- How biologic differences and gendered behaviors may affect outcomes after transplant
- Why more objective referral criteria and allocation systems are important for improving equity
Dr. Foster emphasizes that women benefit significantly from transplantation, but that achieving equitable access and outcomes requires a better understanding of both systemic and biologic factors. The discussion underscores the need for continued research, policy updates, and a shared commitment from transplant professionals to reduce disparities across the transplant pathway.
Episode 25: Behind the Paper: Transplant Surgery: Sustaining a Workforce at a Critical Juncture | Dimitrios Morris, MD
In this Behind the Paper episode, Macey Levan, Social Media Editor for the Transplantation journals, interviews Dimitrios Morris, MD about the key insights from:
📄 Transplant Surgery: Sustaining a Workforce at a Critical Juncture
Commentary
Published in Transplantation — July 2026
This commentary examines the growing challenges facing the transplant surgery workforce at a time when the field continues to evolve through innovation, increasing clinical complexity, and expanding expectations. The conversation explores why workforce sustainability is not only a matter of surgeon well-being, but also essential to maintaining organ utilization, equity, and public trust.
The episode highlights:
- Why transplant surgery is facing declining interest among general surgery residents
- How unpredictable schedules and high-acuity care contribute to workforce strain
- Why fellowship training must better reflect the realities of modern transplant practice
- How academic promotion pathways can better recognize transplant surgeons’ contributions
- The importance of clinical excellence, applied scholarship, and systems leadership
- Why attracting ambitious, idealistic, and resilient future leaders is critical to the field’s future
Dr. Morris emphasizes that sustaining the transplant surgery workforce will require structural reform, not simply individual resilience. The discussion also highlights reasons for optimism, including continued innovation in machine perfusion, expanding surgical techniques, and the field’s growing ability to treat more complex disease processes.
Announcement of 2026 WIT Award Winners
Women in Transplantation is delighted to announce our WIT Award winners for 2026!
Woman Leader in Transplantation
Unsung Hero
Online Program with Abstract Presentations is now available!
Abstract Presenters now displaying in the online program
TTS 2026 - Help Celebrate the People Behind TTS
Upcoming Webinar Presentations
IPTA-ISOT Collaborative Webinar Series
‘Infections in Pediatric Kidney Transplant Recipients: Recurrent UTIs’
Transplantation Journal Highlights
Transplantation Journal - Social Media Content
Transplantation Direct - Social Media Content
TTS at FOCiS 2026
TTS-Sponsored Symposium Highlights Advances in Systems Immunology and Transplant Research at FOCiS 2026 in San Francisco
The Transplantation Society (TTS), in partnership with the American Society of Transplantation (AST) and the American Society for Histocompatibility and Immunogenetics (ASHI), sponsored the symposium “Systems Immunology and Computational Approaches to Characterize Transplant Immunity” at this year's Federation of Clinical Immunology Societies (FOCiS) meeting.
The session brought together approximately 25–30 delegates and featured presentations from three leading experts in the field: David Hildeman (University of Cincinnati), Katherine Bull (University of Oxford), and Megan Sykes (Columbia University). Their talks explored emerging approaches in systems immunology and computational analysis to better understand transplant immunity, sparking lively discussion among attendees.
The symposium continues to serve as an important platform for connecting the transplant community with the broader translational immunology field. By fostering scientific exchange and interdisciplinary collaboration, the session highlighted the growing role of advanced immunological and computational approaches in transplantation research.
TTS's ongoing presence at FOCiS remains an important opportunity to showcase transplantation science within the wider immunology community and strengthen connections with researchers working across related disciplines. The Society is grateful to its partners, AST and ASHI, and to the speakers and attendees who contributed to the success of this year's symposium.
ISUTx 2026 SOTA
Contact
Address
The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada
Используйте Вавада казино для игры с бонусом — активируйте промокод и начните выигрывать уже сегодня!