Tribune Pulse - April 19, 2018 - Volume II - Issue 14

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poll

We will be conducting some micro-surveys to see what is important to the Transplant community. One question at a time, simply click the response to participate!

What DO THINK is the most important thing for TTS to focus on?

  • Education
  • Networking
  • Providing a global forum for international issue
  • Global scientific exchange
  • Public policy

CLICK HERE TO SUBMIT YOUR OPINION

tts2018program

TTS 2018 - Lunch & Learn Sessions are filling up quickly -
reserve your seat!

Lunch and Learn Sessions will feature small groups with a maximum of nine delegates matched with a facilitator of their choice. Sixty groups over a three-day are planned.

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Transplantation DIRECT Journal - Featured Article

Submitted by Dr Peri Kocabayoglu Editorial Fellow, Transplantation.

Adapting the Surgical Apgar Score for Perioperative Outcome Prediction in Liver Transplantation: A Retrospective Study

Pearson ACS, Subramanian A, Schroeder DR, Findlay JY.
Transplant Direct. 2017 ;3(11):e221.

The surgical Apgar score (SAS) entails parameters including the lowest heart rate, lowest mean arterial pressure, and estimated blood loss (EBL). In this retrospective analysis of 628 liver transplantations, the authors developed a modified SAS that can be utilized to predict early morbidity and mortality. This modified version of the SAS, termed SAS-LT, is calculated by replacing the EBL parameter with volume of red blood cells transfused. One hundred five out of 628 liver transplant recipients (16.7%) included in this study demonstrated serious perioperative morbidities or mortalities. The SAS-LT score had a similar predictive ability compared to models for end-stage liver disease, Acute Physiology and Chronic Health Evaluation III, and Sequential Organ Failure Assessment scores. In fact, the SAS-LT proved to be a straightforward intraoperative score predicting death or severe complications within the early postoperative period. Further studies into other intraoperatively measured parameters and variables will be necessary to optimize the approach while the total volume of RBCs transfused during transplantation should be studied as an independent predictor of outcomes.

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Canada - Organ donation by Humboldt Broncos player inspires others - Donation agencies across Canada say registration jumped after bus crash that claimed 15 lives

logan boulet humbolt

Humboldt Broncos defenceman Logan Boulet, 21, was from Lethbridge, Alta. Boulet had recently signed an organ donation card and was kept on life support while matches were found for his organs. He was expected to save the lives of at least six people. (SJHL)

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In the News

Life of a liver awaiting transplantation

April 17 - In a paper published in Nature, Nasralla et al. report the results of a clinical trial that compared two organ storage methods.

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Twenty year collaboration leads to human trial of lung transplant drug

April 19 - Physicians at the University launch regadenoson testing for lung transplant patients

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Man's second face transplant is a world first

April 17 - A man in Paris has become the world's first to successfully receive two facial transplants. Jérôme Hamon, 43, underwent his first face transplantation procedure in 2010 to treat neurofibromatosis, a genetic disorder characterized by the growth of tumors along nerves in the skin, brain and other parts of the body. Yet Hamon's body rejected the original transplant.

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Hepatitis C Treatments Reduce Transplants Therapies also appear to reduce liver-related mortality

April 15 - ARIS -- Since use of direct acting antiviral combination therapies for hepatitis C virus (HCV) infection became widespread, the need for liver transplantation for patients with the infection has plummeted, researchers reported here.

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Risk of Fatal Infection After Kidney Transplant Drops in Finland

April 5 - The risk of death from infection after kidney transplantation dropped by half since the 1990s in Finland, researchers reported.

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Dialysis providers' awareness of racial disparities in transplantation is low

April 12 - The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), point to the need for education and training for clinicians to improve equity in access to transplantation.

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Regenerative Medicine Advanced Therapy: The Latest Special FDA Designation

April 11 - The FDA has programs designed to expedite the drug development and review processes for promising pipeline products. These programs include Accelerated Approval, Breakthrough, Fast Track, and Priority Review designations. The newest of these programs is Regenerative Medicine Advanced Therapy (RMAT).d.

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Risk of Fatal Infection After Kidney Transplant Drops in Finland

April 5 - The risk of death from infection after kidney transplantation dropped by half since the 1990s in Finland, researchers reported.

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Direct-acting antivirals improve liver transplant survival, impact wait-list composition

April 6 - The use of direct-acting antivirals (DAA) is associated with significant improvements in survival in patients undergoing liver transplantation because of hepatitis C virus (HCV)-related liver disease and decreased the number of patients with HCV needing liver transplantation, according to a study published in the Journal of Hepatology.

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Approaching CTEPH Metabolically and Surgically at the 38th Annual International Society for Heart and Lung Transplantation (ISHLT) Annual Meeting & Scientific Sessions

April 11 - Today at the 38th Annual International Society for Heart and Lung Transplantation (ISHLT) Meeting & Scientific Sessions, researchers shared results during Wednesday’s Cutting Edge CTEPH: From Metabolomics to Surgical Technique presentations.

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Belarus' accomplishments in organ transplantation emphasized

April 6 - Belarus ranks 24th among the world's most developed countries in terms of transplantation, BelTA learned from Belarusian Healthcare Minister Valery Malashko at the international science and practice conference “Ten years of liver transplantation in the Republic of Belarus: ethical challenges, results and perspectives” in Minsk on 6 April.

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Canada - 4,500 Manitobans sign organ donor cards after Humboldt

April 13 - The number of Manitobans registering to be organ donors has skyrocketed in the week since the deadly Humboldt Broncos bus crash.

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Kidneys Initially Deemed Unfit For Transplant Prove Viable, Study Shows

April 11 - The first study to track outcomes of transplanted kidneys that were previously deemed unfit for transplant shows a more than 90 percent graft survival rate for these kidneys a year after patients received them.

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Bluetooth program gives lung transplant patients brighter outlook

April 17 - A pilot program conducted by Keck Medicine of USC has succeeded in alleviating problems faced by patients on post-lung transplant regimens. A failure by the patients to monitor their health and stick to medication schedules can lead to serious complications — from infection to rejection of a transplanted lung.

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Pig may come to rescue of renal failure patient: Experts

April 14 - In the coming five years, the kidney of pigs can be used to treat the renal failure patients. If the government will relax some of its guidelines, then a person sitting in the US can donate his kidney to a matching donor in India or vice-versa through global paired donation.

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