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Tribune Pulse - May 31, 2019 - Volume III - Issue 21

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Transplantation Expert Dr. Matthew Cooper will receive NKF’s New Excellence Award

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New York, NY – May 6, 2019 —The National Kidney Foundation (NKF) will present its first ever award for Excellence in Kidney Transplantation to Matthew Cooper, MD, at NKF’s 2019 Spring Clinical Meetings in Boston in May.

Dr. Cooper is a Professor of Surgery at Georgetown University School of Medicine and the Director of Kidney and Pancreas Transplantation at the Medstar Georgetown Transplant Institute.  He is a pioneer in the laparoscopic donor nephrectomy procedure and in the field of Paired Kidney Exchange (PKE).  He conducts critical work to remove barriers for living organ donors. He is co-chair of the National Kidney Foundation’s  Transplantation Task Force to reduce the rate of discarded, deceased-donor kidneys...

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Fifth International Transplant Conference, at University of Warwick, Coventry, U.K on 9th, 10th May 2019

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From left to right: Satya Sharma, MBE, DL, Ambassador NHSBT, U.K; Sunil Shroff, MOHAN Foundation, India; Paul Sabapathy Former Lord Lieutenant OBE, CVO, U.K; Nithya Krishnan, UHCW, U.K; Lord Lieutenant John Crabtree OBE, Chairman of Commonwealth Games 2022, U.K; Marcelo Cantarovich, President Elect, TTS.

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Attendees of the Fifth International Transplant Conference. The event brought more than 80 people together to discuss how to overcome the clinical, scientific and social barriers surrounding kidney transplantation.

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TRANSPLANTATION - WEEK'S MOST DOWNLOADED PAPER

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Transplantation - Highlighted Article

Dr. Karen Keung, Editorial Fellow, Transplantation

Patient Functional Status at Transplant and Its Impact on Posttransplant Survival of Adult Deceased-donor Kidney Recipients

Bui K, Kilambi V, Rodrigue JR, et al.
Transplantation 2019; 103 (5): 1051–1063

The functional status of patients at the time of transplantation, as measured by the Karnofsky performance score (KPS) ranging from 0 to 100, is recorded in the Scientific Registry of Transplant Recipients (SRTR) and Organ Procurement and Transplantation Network (OPTN) data. Using these data from a cohort of deceased donor kidney transplant recipients, 1-year and 3-year models for post-transplant survival were fitted with current SRTR variables and KPS, to enable comparative analyses between the SRTR model with and without KPS augmentation. KPS was validated to be a significant predictor of post-transplant survival. Using the augmented model and stratified by score, KPS 10 to 30 recipients have the worst expected survival probabilities in 3 years, significantly decreasing to below 50% from after 1 year. Even with the best kidney quality based on a kidney donor profile index (KDPI) of 0, these recipients have at most 60% expected 3-year survival probabilities. However, expected survival probabilities improve with increasing KPS, and in the next stratum of KPS 40-50, predicted survival is much better even with low-quality kidneys. These findings suggest that inclusion of functional status into SRTR’s risk-adjusted models should be considered, to aid in current listing and transplantation decisions and strategies.

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Webinar | Learn how easy it is to apply for the ISN-TTS Sister Transplant Centers Program

When?

June 24 AT 2 PM CEST. Check when this webinar is happening in your timezone, here.

Speakers

Peter Kerr, Chair of the ISN Sister Centers Programs, and Philip J. O’Connell, Past-President of The Transplantation Society and Director of Transplantation, will guide you through each step of the application process.

They will share some handy tips on how to prepare a successful application and answer any questions you may have.

About the ISN-TTS Sister Transplant Centers Program

The ISN-TTS Sister Transplant Centers Program link renal and transplant centers in low-resource countries with established centers so they can benefit from educational support and work together to increase opportunities for kidney patients.

CLICK HERE TO Register

TTS Education Committee - Symposium Program Development

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TTS will consider assisting in developing the program of a Symposium that contributes to the field of transplantation and adheres to the highest scientific and educational standards. The program should be in the beginning stages of development to be considered. It is important that the TTS Education Committee (EC) only work on symposia that fully fit the TTS ethical guidelines.

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MAY 21 WEBINAR
In case you missed it ... the Recording is NOW POSTED

EC Liver Series v2

TITLE: MULTIDISCIPLINARY CARE MODEL FOR OPTIMAL MANAGEMENT OF THE NASH LIVER TRANSPLANT WAITLIST CANDIDATE
TUESDAY, MAY 21, 2019 - 4:00 PM EDT (MONTREAL TIME)

Overview:

Dr. Mehal will speak on implementation of multidisciplinary care model - pharmacological weight loss therapy in advanced liver disease and special considerations for the sarcopenic obese patient.

Dr. Posselt will speak on bariatric surgery: approach and special considerations in advanced liver disease.

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TTS Is Exhibiting at The ATC 2019 in Boston

CLICK HERE TO VISIT ATC 2019 WEBSITE

Young Members Committee Activities at ATC

AST WHCOP and TTS WIT Joint Networking Event at ATC 2019

Please join the Women's Health Community of Practice (WHCOP) and the TTS Women in Transplantation (WIT) for an exciting joint networking event on Tuesday, June 4, 6:00 – 7:30 pm at the Sheraton Boston Home (Back Bay D).

Guest speaker Dr. Julie R. Ingelfinger and members of WHCOP and WIT will discuss the critical role of our memberships in supporting careers, research, and leadership for female transplant professionals.

Tuesday June 4 6:00-7:30 pm
Sheraton Boston Home (Back Bay D), 39 Dalton St., Boston, MA

Refreshments and light fare will be served.

Our Quarterly Newsletter, The Tribune, Released! • Spring 2019 Issue

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IN THE NEWS

Surprising research result: All immature cells can develop into stem cells

May 16 - A new study conducted at the University of Copenhagen challenges traditional knowledge of stem cell development. The study reveals that the destiny of intestinal cells is not predetermined, but instead determined by the cells' surroundings. The findings may make it easier to manipulate stem cells for stem cell therapy. Results have just been published in Nature.

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Placental Stem Cells Can Regenerate the Heart After Heart Attack

May 20 - Researchers at the Icahn School of Medicine at Mount Sinai have demonstrated that stem cells derived from the placenta known as Cdx2 cells can regenerate healthy heart cells after heart attacks in animal models. The findings, published in the May 20 issue of Proceedings of the National Academy of Sciences (PNAS), 1 may represent a novel treatment for regenerating the heart and other organs.

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Zebrafish Help Researchers Explore Alternatives to Bone Marrow Donation

May 20 - UC San Diego researchers discover new role for epidermal growth factor receptor in blood stem cell development, a crucial key to being able to generate them in the laboratory.

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Cerebrovascular Disease: A Serious Complication After Allogeneic Hematopoietic Stem Cell Transplantation

May 20 - A study published in the International Journal of Hematology found that the incidence of cerebrovascular disease (CVD) was approximately 10 times higher in patients after allogeneic hematopoietic stem cell transplantation (HSCT) compared with the general Taiwanese population. Moreover, CVD was associated with the number of high-dose cytarabine courses given.

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Kidney Transplant Rejection Linked to New Mismatch Locus

May 16 - A team led by investigators at Columbia University has identified a new form of genetic mismatch, or "genomic collision," between kidney transplant recipients and organ donors that appears to increase the risk of allograft rejection.

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DAAs Enable HCV-Infected Heart, Lung Transplants

May 13 - A short, "post-exposure" course of treatment with directing-acting antivirals (DAAs) enabled successful transplantation of hepatitis C virus (HCV)-infected hearts and lungs to uninfected recipients in a new trial of "HCV-mismatched" transplantations. The trial expands on earlier studies with kidney and liver transplantation from infected donors, which suggest the feasibility of treatment of HCV infection early after transplantation.

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Upcoming Meetings and ANNOUNCEMENTS

TOND-TDTD - Abstract Submission DEADLINE Extended - MAY 31

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We are pleased to invite you to present your work at the 3rd Joint Meeting of the Turkish Transplantation Society and the Turkic World Transplantation Society which will be held on October 10-11, 2019 in Tashkent, Uzbekistan.

Abstract submission will commence on February 1, 2019 and close on May 31, 2019.

Abstracts shall be accepted by email. Please visit https://tondtdtd2019.meetinghand.com/en/ for detailed instructions on abstract submission and to download an abstract submission form. Please note that abstracts sent by fax or regular mail will not be accepted. Abstracts submitted after the closing date will not be considered.

CLICK TO VIST THE WEBSITE

International Transplantation Science Meeting 2019

ITS 2019 is set for Nov. 10-13 in Clearwater Beach, Florida. Keynote speakers include Katherine High, President and Head of R&D at Spark Therapeutics, and Ronald Germain, chief of Laboratory of Immune System Biology and Lymphocyte Biology Section at the National Institute of Allergy and Infectious Diseases National Institutes of Health.

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Click Here for Registration

Click Here for Abstract Submission

IPITA 2019 LYON - France

Registration is open and preliminary program is available.

CLICK HERE TO VISIT IPITA2019.ORG

TID2019 - REGISTRATION NOW OPEN!

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VISIT WWW.TID2019.ORG FOR FULL DETAILS

IXA 2019 - Late Breaking abstract Submission open until June 1

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VISIT WWW.IXA2019.ORG FOR FULL DETAILS

TTS-ISODP Award's Application Deadline June 3

The scientific awards are designed to help offset expenses incurred to attend the ISODP Congress and awarded based on the scientific merit of applicants. Therefore, recipients must attend the meeting in order to receive this award. If an awardee is selected for a scientific award but does not attend the meeting, the monies of the award will be forfeited.

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VISIT WWW.ISODP2019.ORG FOR FULL DETAILS

CTRMS 2019 – Lesvos - Greece

Late-Breaking and Poster Abstract Submissions are now being accepted!

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CLICK TO GO TO THE CTRMS 2019 WEBSITE

CIRTA 2019 - PARIS, FRANCE

CLICK HERE TO VISIT CIRTA2019.ORG