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Bloodstream Infection in Allogeneic Hematopoietic Cell Transplant Recipient

9651.1 - Bloodstream Infection in Allogeneic Hematopoietic Cell Transplant Recipient: Thinking Beyond The Usual

Presenter: Kim, Yeoh, Melbourne, Australia
Authors: Kim Yeoh, Cornelia Lass-Flörl, Frédéric Lamoth, Dionysios Neofytos


Dionysios Neofytos, Switzerland
Moderator
Bio

Kim Yeoh, Australia
Speaker
Bio

Cornelia Lass-Flörl, Austria
Speaker
Bio

Frédéric Lamoth, Switzerland
Speaker
Bio

Overview

Allogeneic hematopoietic cell transplant recipient with acute myeloid leukemia and multiple myeloma who underwent cytarabine and daunorubicin (7+3) induction chemotherapy followed by cytarabine (HiDAC) consolidation, post fludarabine, melphalan and thymoglobulin conditioning regimen, with failure to engraft, requiring autologous stem cell rescue and buffy coat and granulocyte transfusions, eventually presenting with persistent neutropenic fever and positive blood cultures.

Learning Objectives

  1. Optimizing the diagnostic and treatment approach in the management of otherwise unexplained neutropenic fever in allogeneic hematopoietic cell transplant recipients.
  2. Differential diagnosis of bloodstream infections in allogeneic hematopoietic cell transplant recipients.
  3. Expanding the list of organisms found in positive blood cultures in highly immunocompromised hosts.


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