International Basic and Translational Science Mentee-Mentor Awards
THE TRANSPLANTATION SOCIETY (TTS), ALONG WITH THE COLLABORATION OF NATIONAL AND INTERNATIONAL SOCIETIES, ACKNOWLEDGES THE CONTRIBUTION OF BASIC SCIENCE TO THE FIELD OF TRANSPLANTATION.
The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Basic and Translational Science Mentee-Mentor Awards to recognize the efforts of scientists who have advanced our understanding of transplantation science and fostered the development of the young investigators who will be the future leaders in our field.
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TTS-AST International Mentee-Mentor Award
Liver exosomes after hepatic ischemia-reperfusion injury differentially affect bone marrow-derived versus liver-resident dendritic cell function
Mentee: Cindy Avalos de Leon, United States
Mentor: Angus Thomson, United States
TTS-CST International Mentee-Mentor Award
ABO-incompatible transplantation following enzymatic A-antigen removal in a mouse model: A-antigen re-expression and prevention of early antibody-mediated rejection
Mentee: Tate Erickson, Canada
Mentor: Lori J. West, Canada
Graft protein shows a distinct signature in donor-specific antibody positive kidney transplant recipients with antibody-mediated rejection
Mentee: Kieran Manion, Canada
Mentor: Ana Konvalinka, Canada
TTS-FOCIS International Mentee-Mentor Award
OuTSMARTing donor specific antibodies (DSA): De novo DSA are preceded by a lack of specific regulation of CD4+ Th-1 Cells to DSA antigens but not other donor mismatches
Mentee: Sumoyee Basu, United Kingdom
Mentor: Kate Bramham, United Kingdom
Molecular and spatial profiling of GMP-Grade Tregs in kidney transplantation
Mentee: Nora Atallah, United Kingdom
Mentor: Fadi Issa, United Kingdom
TTS-JST International Mentee-Mentor Award
Adverse effects of graft congestion and ameliorative effects of hepatocyte growth factor after liver transplantation in rats
Mentee: Hikaru Aoki, Japan
Mentor: Takashi Ito, Japan
Up-regulated LRRN2 expression is effective as a marker for graft quality in living donor liver transplantation
Mentee: Takahiro Tomiyama, Japan
Mentor: Tomaharu Yoshizumi, Japan
TTS-KST International Mentee-Mentor Award
Exploring the Molecular Pathways of Intracranial Aneurysm Formation in Autosomal Dominant Polycystic Kidney Disease using Proteomic Analysis
Mentee: Jin-Myung Kim, Republic of Korea
Mentor: Sung Shin, Republic of Korea
TTS-NVT International Mentee-Mentor Award
Interpretable prediction of kidney allograft rejection using machine learning: A comparison between linear and non-linear models
Mentee: Alvaro Assis de Souza, The Netherlands
Mentor: Karin Boer, The Netherlands
Tissue-resident memory T cells in human kidney transplants have alloreactive potential
Mentee: Hector Tejeda, The Netherlands
Mentor: Carla Baan, The Netherlands
Polarized HLA class I expression on renal tubules hinders the detection of donor-specific urinary extracellular vesicles
Mentee: Liang Wu, The Netherlands
Mentor: Karin Boer, The Netherlands
TTS-SET International Mentee-Mentor Award
Tobacco Influence on Short-Term Outcomes of Liver Transplantation
Mentee: Alba Gómez Barrena, Spain
Mentor: Iago Justo Alonso, Spain
TTS-TSANZ International Mentee-Mentor Award
Targeting CD47 improves islet function and survival
Mentee: Atharva Kale, Australia
Mentor: Natasha Rogers, Australia
Improved recovery of rat hearts after prolonged cold storage by acid sensing ion channel (ASIC) inhibitor Hi1a varies with preservation solution
Mentee: Sanjay Dutta, Australia
Mentor: Peter Macdonald, Australia
TTS International Mentee-Mentor Award
VISTA alleviates post-transplantation acute rejection by modulating ERK pathway and macrophage polarization
Mentee: Lifei Liang, People’s Republic of China
Mentor: Cheng Yang, People’s Republic of China
A retained native kidney (with ureter ligation) prevents dehydration and calcium/phosphate imbalance after life-supporting TKO pig-to-baboon kidney transplantation
Mentee: Kohei Kinoshita, United States
Mentor: David Cooper, United States
Interleukin-6 blockade prevents costimulation blockade-resistant allograft rejection by promoting intragraft regulation
Mentee: Moritz Muckenhuber, Austria
Mentor: Thomas Wekerle, Austria
Lactate remodulates the OXPHOS of Tregs by inducing N-glycosylation in mitochondria via transcription and translocation of MGAT1
Mentee: Jinren Zhou, People’s Republic of China
Mentor: Ling Lv, People’s Republic of China
Re-assessing the Determination of Sensitization Status in Kidney Transplant Candidates: Unveiling persistent Anti-HLA Antibodies in waitlisted Patients
Mentee: Friederike Martin, United States
Mentor: Stefan G. Tullius, United States
Immunological effects of Abdominal Rectus Fascia transplant in rats without immunosuppression, in the short and medium term
Mentee: Jeremias Moreira, Argentina
Mentor: Gabriel Gondolesi, Argentina
MHC class II sharing promotes donor treg-mediated tolerance after intestinal transplantation in swine
Mentee: Muhammed Esad Gunes, United States
Mentor: Joshua Weiner, United States
TTS-CST International Mentee-Mentor Award
The role of role of sex and T cells in natural vs induced ABO antibody production in mice
Mentee: Adam Ibrahim, Canada
Mentor: Lori J. West, Canada
Establishing the most physiological
perfusion milieu for normothermic ex vivo pancreas perfusion in porcine
models: How far have we reached?
Mentee: Samrat Ray, Canada
Mentor: Trevor Reichman, Canada
TTS-SMT International Mentee-Mentor Award
New index for prediction of massive blood transfusion
Mentee: Blanca Otero Torrón, Spain
Mentor: Iago Justo, Spain
TTS-SET International Mentee-Mentor Award
Preliminary results of the first
clinical trial to prevent graft rejection in heart transplant children
employing a cellular therapy with autologous Treg obtained from thymic
tissue (thyTreg)
Mentee: Esther Bernaldo-de-Quirós, Spain
Mentor: Rafael Correa-Rocha, Spain
TTS-TSANZ International Mentee-Mentor Award
Single Cell Alloreactive TCR Repertoire Profiling
Mentee: Moumita Paul-Heng, Australia
Mentor: Alexandra Sharland, Australia
Factors determining the ex-vivo survival
of human livers more than 1 week under normothermic conditions:
understanding the requirements for long-term survival of organs
Mentee: Ngee-Soon Lau, Australia
Mentor: Carlo Pulitano, Australia
TTS-SFT International Mentee-Mentor Award
Expression of TNFR2 and CD29 define a highly suppressive subset of human CD8+ T regulatory cells
Mentee: Céline Sérazin, France
Mentor: Carole Guillonneau, France
TTS-KST International Mentee-Mentor Award
Anti-C4d chimeric antigen receptor regulatory T cells suppressed allograft rejection in ABO-incompatible heart transplantation
Mentee: Gwangmin Lee, Korea
Mentor: Jaeseok Yang, Korea
Mono-maintenance therapy with anti-ICAM-1 monoclonal antibody induced long-term liver allograft survival in nonhuman primates
Mentee: Dongkyu Han, Republic of Korea
Mentor: Jaeseok Yang, Republic of Korea
TTS-ISOT La Renon International Mentee-Mentor Award
Chronic antibody-mediated rejection in
patients transplanted with renal allografts activates an inflammatory
amplifying loop (IL-6+IL-17) when prolonged IL-6 secretion occurs
Mentee: Mantabya Singh, India
Mentor: Vivek B. Kute, India
Comparative study of medium term outcomes of ABO incompatible kidney transplantation with ABO compatible kidney transplantations
Mentee: Sushree Sashmita Das, India
Mentor: Deepak Shankar Ray, India
Impact of single centre 440 kidney exchange transplantation over 20 years to increase living donor pool in India: a cohort study
Mentee: Hari Shankar Meshram, India
Mentor: Vivek B. Kute, India
Impact of gender on kidney
transplantation practices: A single centre report from largest
public-sector transplant center of India
Mentee: Sanshriti Chauhan, India
Mentor: Himanshu Patel, India
Gender disparity- a battle ongoing
Mentee: Varsha Totadri, India
Mentor: Vasanthi Ramesh, India
Preliminary results of ex-vivo
normothermic machine perfusion in deceased donor renal allograft
transplantation – first clinical experience from Asia
Mentee : Devprakash Choudhary, India
Mentor: Ashish Sharma, India
Organ preserving cardiopulmonary resuscitation in a resource limited country to increase donor pool
Mentee: Mayur Patil, India
Mentor: Pankaj Shah, India
CYP3A5 polymorphism in renal transplantation: a key to personalized medicine
Mentee: Prasad Gurjar, India
Mentor: Amit Pasari, India
TTS-STALyC International Mentee-Mentor Award
Gender disparities in renal replacement therapies in Colombia
Mentee: Laura Niño Torres, Colombia
Mentor: Fernando Giron, Colombia
TTS-SAT International Mentee-Mentor Award
Implementation of longitudinal
portoplasty for hypoplasic portal veins in children with biliary atresia
in a liver transplantation centre in Argentina
Mentee: Maria Julia Minetto, Argentina
Mentor: Marcelo Dip, Argentina
The potential role of HLA molecular mismatch in biopsy-proven rejection in pediatric liver transplantation
Mentee: Guido Trezeguet Renatti, Argentina
Mentor: Oscar Imventarza, Argentina
TTS International Mentee-Mentor Award
Mitochondrial complex V inhibition
enhances human regulatory T cell suppressive function through the
induction of immunosuppressive small extracellular vesicles
Mentee: Hisashi Hashimoto, United Kingdom
Mentor: Fadi Issa, United Kingdom
Donor dendritic cell depletion allows
novel insights into the alloimmune response following murine composite
tissue and skin transplantation
Mentee: Barbara Kern, Germany
Mentor: Stefan G. Tullius, United States
The role of co-expressing MHC class I molecules in pig endothelial cells: a case for HLA-E and HLA-G in xenotransplantation
Mentee: Arthur Cross-Najafi, United States
Mentor: Burcin Ekser, United States
PGC1alpha-mediated metabolic
reprogramming facilitates M1 macrophage polarization during steatotic
allograft dysfunction after liver transplantation
Mentee: Jiang Liu, People’s Republic of China
Mentor: Jiahong Dong, People’s Republic of China
The Molecular Nature of the Banff iIFTA Lesion
Mentee: Harry Robertson, Australia
Mentor: Natasha Rogers, Australia
THE TRANSPLANTATION SOCIETY (TTS), ALONG WITH COLLABORATION OF NATIONAL AND INTERNATIONAL SOCIETIES, ACKNOWLEDGES THE CONTRIBUTION OF BASIC SCIENCE TO THE FIELD OF TRANSPLANTATION
The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Travel Awards by recognizing the efforts of scientists who have advanced our understanding of transplant science and fostered the development of the young investigators who will be the future leaders in our field.
TTS-CST International Transplantation Science Mentee-Mentor Awards
TTS-TSANZ International Transplantation Science Mentee-Mentor Awards
| Mentee: Hong Chee Chew, Australia | Mentor: Peter MacDonald, Australia |
| Mentee: Sam Adhikary, Australia | Mentor: Debbie Watson, Australia |
TTS-TOND International Transplantation Science Mentee-Mentor Awards
| Mentee: Selin Akad, Turkey | Mentor: Feride Sahin, Turkey |
TTS-JST International Transplantation Science Mentee-Mentor Awards
| Mentee: Asuka Tanaka, Japan | Mentor: Yuka Tanaka, Japan |
TTS-ISOT International Transplantation Science Mentee-Mentor Awards
TTS-International Transplantation Science Mentee-Mentor Awards
TTS-SET International Transplantation Science Mentee-Mentor Awards
| Mentee: Patricia Conde -San Román, Spain | Mentor: Jordi Ochando, Spain |
| Mentee: María García-Conde Delgado, Spain | Mentor: Iago Justo, Spain |
| Mentee: Oana Anisa Nutu, Spain | Mentor: Iago Justo, Spain |
TTS-NTV International Transplantation Science Mentee-Mentor Awards
| Mentee: Jesus M. Sierra Parraga, Netherlands | Mentor: Martin Hoogduijn, Netherlands |
TTS/ISOT AWARDS
These awards were made possible with the contribution of the Indian Society of Organ Transplantation.
Shweta Tyagi, India – Mentee / Uma Kanga, India – Mentor
EXPRESSION OF SHLA-G IDENTIFIES FAVORABLE OUTCOME IN RENAL TRANSPLANT RECIPIENTS
Sahil Bagai, India – Mentee / Manish Rathi, India – Mentor
CORRELATION OF PRETRANSPLANT GLUCOSE METABOLISM WITH THE DEVELOPMENT OF NEW ONSET DIABETES AFTER RENAL TRANSPLANTATION
TTS/JST AWARDS
These awards were made possible with the contribution of the Japan Society for Transplantation.
Nobuki Ishida, Japan – Mentee / Kohei Ishiyama, Japan – Mentor
SUPPRESSING LIVER NATURAL KILLER CELLS ACTIVATION BY COTRANSPLANTATION OF PREACTIVATED MESENCHYMAL STEM CELLS CONTRIBUTES TO IMPROVEMENT OF ISLET GRAFT SURVIVAL
Masakatsu Kaneshiro, Japan – Mentee / Atsushi Yoshizawa, Japan – Mentor
ANALYSIS OF HUMAN LEUCOCYTE ANTIGEN CLASS II EXPRESSION IN GRAFT LIVER TISSUE; DONOR SPECIFIC ANTIBODIES AND GRAFT LIVER FIBROSIS
TTS/NTV AWARDS
This award was made possible with the contribution of the Nederlandse Transplantatie Vereniging.
Fleur Peters, The Netherlands – Mentee / Karin Boer, The Netherlands – Mentor
IDENTIFICATION OF KIDNEY TRANSPLANT PATIENTS AT RISK FOR SKIN CANCER BY DIFFERENTIALLY METHYLATED REGIONS IN T CELLS
TTS/SET AWARDS
This award was made possible with the contribution of the Sociedad de Española Trasplante
Rebeca Arroyo-Hornero, UK – Mentee / Fadi Issa, UK – Mentor
MODULATION OF CD27/CD70 CO-STIMULATORY PATHWAY MAY ALLOW FOR THE GENERATION OF A MORE POTENT HUMAN REGULATORY T CELL PRODUCT FOR CELL THERAPY
TTS/TSANZ AWARDS
These awards were made possible with the contribution of The Transplantation Society of Australia and New Zealand.
Mario Leong, Australia – Mentee / Alexandra Sharland, Australia – Mentor
RECOGNITION OF INTACT DONOR CLASS I BY RECIPIENT CD8+ T CELLS IS REQUIRED FOR TOLERANCE INDUCTION FOLLOWING LIVER-DIRECTED TRANSGENE EXPRESSION
Paul Wilcox, Australia – Mentee / Bruce M. Hall, Australia – Mentor
CD8 EXPRESSION INCREASES SUPPRESSIVE ABILITY OF CD4+CD25+TREG AND IS A MARKER OF ANTIGEN-SPECIFICITY
TTS AWARDS
These awards were made possible with the contribution of The Transplantation Society.
Xiaomeng Hu, USA – Mentee / Sonja Schrepfer, USA - Mentor
GENERATION OF HYPOIMMUNOGENIC INDUCED PLURIPOTENT STEM CELLS FOR ALLOGENEIC CELL AND TISSUE TRANSPLANTATION
Timm Heinbokel, USA – Mentee / Stefan G. Tullius, USA – Mentor
A SHIFTING BALANCE: INNATE IMMUNITY IMPACTS CHARACTERISTICS AND SPECIFICITY OF ALLOIMMUNE RESPONSES IN AGING.
Yoshihiro Ono, USA – Mentee / Angus Thomson, USA – Mentor
GRAFT-INFILTRATING PD-L1HI CROSS-DRESSED DENDRITIC CELLS SUBVERT DONOR-REACTIVE T CELL RESPONSES IN MOUSE LIVER TRANSPLANT TOLERANCE.
Gaelen Dwyer, USA – Mentee / Heth Turnquist, USA – Mentor
THE “TYPE 2” CYTOKINE, INTERLUKIN-33, GENERATES POTENT
The Transplantation Society (TTS) along with the collaboration of its Affiliated Societies celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Awards by recognizing the efforts of basic scientists who have advanced our understanding of transplant science/immunobiology and/or treatment of transplant recipients, and the young investigators who will be the future leaders in transplantation.
The Awards were given on Sunday, August 21, during the International Transplantation Science Mentee-Mentor Networking Event held from 18:30 to 19:30 in the Hong Kong Convention and Exhibition Center.
- AMP-activated protein kinase attenuated marginal liver graft injury via promoting mitochondrial biogenesis and respiratory function
Mentee: Jiang Liu, Hong Kong
Mentor: Chung Mau Lo, Hong Kong - CD45RA identifies TSDR demethylated regulatory T cells with a stable phenotype and suppressive cytokine profile
Mentee: Rebeca Arroyo Hornero, United Kingdom
Mentor: Kathryn Wood, United Kingdom - Effect of epigenetic modifications in graft kidneys progressing to chronic allograft dysfunction
Mentee: Sai Vineela Bontha, United States
Mentor: Valeria Mas, United States - The clinical significance and potential therapeutic role of GPx3 in tumor recurrence after liver transplantation
Mentee: Xiang Qi, Hong Kong
Mentor: Nancy Kwan Man, Hong Kong - Vascular sequestration of donor-specific antibodies protects allogeneic islets from humoral rejection
Mentee: Chien-Chia Chen, France
Mentor: Olivier Thaunat, France - Human anti thrombotic genes do not obviate the need for anticoagulation in aiding long term xenograft survival
Mentee: Joshua Chan, United States
Mentor: Muhammad Mohiuddin, United States
- Prospective treatment and novel biomarkers of BK polyomavirus associated nephropathy
Mentee: Minal Borkar, Canada
Mentor: Lori J. West, Canada
- Cell-free mitochondrial DNA activates DCs in an age-dependent fashion and compromises the survival of older grafts
Mentee: Midas Seyda, Germany
Mentor: Stefan G. Tullius, United States - Metabolites associated with bariatric surgery reverse accelerated rejection and augmented alloimmunity in obese allograft recipients
Mentee: Markus Quante, United States
Mentor: Stefan G. Tullius, United States
- Impact of single Centre kidney paired donation transplantation to increase donor pool in India
Mentee: Vivek Kute, India
Mentor: Pankaj R. Shah, India - Imbalance of T helper 17 cells and T regulatory cells is associated with chronic active antibody mediated rejection in renal allograft recipients
Mentee: Brijesh Yadav, India
Mentor: Narayan Prasad, India - Peripheral NK-cell repertoire distribution in chronic allograft dysfunction after renal transplantation Sailaja
Mentee: Kesiraju, India
Mentor: Sahariah Sarbeshwar, India - Ultra-high resolution non-contrast imaging for chronic rejection monitoring and procedural planning in reconstructive transplantation
Mentee: Shailesh Raval, India
Mentor: Vijay Gorantla, India - Development of de-novo donor specific antibody (DSA) and vitamin D status after renal transplantation
Mentee: Sonia Mehotra, India
Mentor: RajKumar Sharma, India
- Clinical and immunological significance of controlling portal vein pressure in living donor liver transplantation
Mentee: Kazuhiro Taguchi , Japan
Mentor: Takashi Onoe, Japan - Systemic therapy of regulatory dendritic cells derived form induced pluripotent stem cells allows allogeneic cardiac grafts acceptance
Mentee: Songjie Cai, Japan
Mentor: Shiro Takahara, Japan - Various pathogenic microbes induce CNI- resistance in B-cells responding to blood group antigens through TLR–MyD88 pathway
Mentee: Hiroshi Sakai, Japan
Mentor: Yuka Tanaka, Japan
- Belatacept fails to inhibit donor-reactive Tfh-B cell interaction, but favors a regulatory transitional B cell profile over tacrolimus
Mentee: Gretchen de Graav, Netherlands
Mentor: Carla Baan, Netherlands
- Interleukin-34 is a Treg-specific cytokine and mediates transplant tolerance
Mentee: Séverine Bézie, France
Mentor: Carole Guillonneau, France
- Pre-transplant AT1Rabs are associated with acute rejection in 2-haplotypes kidney transplant recipients
Mentee: José Manuel Arreola Guerra, Mexico
Mentor: Luis Eduardo Morales Buenrostro, Mexico
- Dendritic cell phenotype and function modification with targeted porous silicon nanoparticles
Mentee: Sebastian Olivier Stead, Australia
Mentor: Patrick Coates, Australia - Surface modification of porcine aortic endothelial cells with Corline Heparin Conjugate (CHC) protects against xenogeneic thrombosis and inflammation
Mentee: Anjan Bongoni, Australia
Mentor: Peter Cowan, Australia - Risky organs: trends in comorbidities among potential and actual Australian organ donors in New South Wales
Mentee: Imogen Thomson, Australia
Mentor: Angela C. Webster, Australia - Disruption of CD8-coreceptor binding abrogates tolerance induction via liver- directed expression of donor MHC class I
Mentee: Moumita Paul-Heng, Australia
Mentor: Alexandra Sharland, Australia
- Rapamycin and retinoic acid downregulate the methylation of FoxP3 after restimulation in human Treg derived from naïve T cells
Mentee: Enzo Candia, Chile
Mentor: Juan Alberto Fierro Correa, Chile - TLR4/CXCL10/CXCR3 signaling mobilized regulatory T cells promote liver tumor recurrence after transplantation
Mentee: Chang-Xian Li, China
Mentor: Nancy Kwan Man, China - Endogenous graft-specific T cell populations exhibit distinct TCR Avidity profiles during acute rejection and tolerance
Mentee: Michelle Miller, United States
Mentor: Maria-Luisa Alegre, United States - The effects of valsartan on klotho expression and oxidative stress in preventing of calcinurine inhibitor nephropathy
Mentee: Sina Raeisi, Iran
Mentor: Hassan Argania, Iran - Prolonged Survival of Porcine Skin on Baboons following Administration of Porcine Cells Expressing Human CD47
Mentee: Aseda Tena, United States
Mentor: David Sachs, Unites States - Delayed CTLA-4Ig treatment of established acute allograft rejection successfully abrogates ongoing B cell responses
Mentee: James Young, United States
Mentor: Anita Chong, United States
- Potent Suppression of allogeneic and xenogeneic immunity by cryopreserved regulatory T cells (Tregs) isolated and expanded from human thymus
Mentee: Esme Dijke, Canada
Mentor: Lori West, Canada - Tailoring Homing Capacity of Thymic regulatory T Cells by Expansion in Cytokline-enriched culture conditions
Mentee: Romy Hoeppli, Canada
Mentor: Megan Levings, Canada
- Ciclosporine A, but not rapamycin, downregulates T-bet in CD8 T cells leading to a diminished anti-tumor activity against B16 melanoma in mice
Mentee: Philip Renner, Germany
Mentor: Edward Geissler, Germany
- Ex vivo generation of alloantigen-specific T regulatory cells using selective T-cell co-stimulation blockade
Mentee: Masaaki Watanabe, Sweden
Mentor: Bo-Goran Ericzon, Sweden
- Bacterial pathogens provoke B cells responding to blood group A-antigens to be resistant to calcineurin inhibitors through TLR - MyD88 pathway
Mentee: Hiroshi Sakai, Japan
Mentor: Yuka Tanaka, Japan - Propagated NK cells from human pluripotent stem cells exert vigorous cytotoxicity against HCC and inhibit HCV replication
Mentee: Selichi Shimizu, Japan
Mentor: Yuka Tanaka, Japan
- P2X7 blockade reduces interferon gamma in a humanised mouse model of graft-versus-host disease
Mentee: Nicholas Geraghty, Australia
Mentor: Debbie Watson, Australia - Autophagy-dependent TIGIT positive Helios positive regulatory T cells are critical for controlling GVHD after allogeneic stem cell transplantation
Mentee: Laetitia Le Texier, Australia
Mentor: Kelli P. MacDonald, Australia - Characterisation of the immunomodulatory action of a unique anti-CXCR3 monoclonal antibody exploiting a conserved human and murine epitope for transplantation
Mentee: Suzanna Pilgrim, Australia
Mentor: Shane Grey, Australia - Microarray gene profile study of immunosuppressive interleukin-17A preactivated human Mesenchymal Stem Cells
Mentee: Kisha N. Sivanathan, Australia
Mentor: Patrick T. Coates, Australia - Genetic polymorphisms in donor tissue determinetransplant outcomes
Mentee: Nathan Zammit, Australia
Mentor: Shane Grey, Australia
2014 INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE–MENTOR AWARDS
- Mentee: Charles Colin Brinkman, United States
Mentor: Dr. Jonathan Bromberg, Unites States - Mentee: Estafania Nova Lamperti, United Kingdom
Mentor: Dr. Maria Hernandez-Fuentes, United Kingdom - Mentee: Yuk Man (Kevin) Lei, United States
Mentor: Dr. Maria-Luisa Alegre, Unites States - Mentee: Niloufar Safinia, United Kingdom
Mentor: Prof. Giovanna Lombbardi, United Kingdom
- Mentee: Shanil Keshwani, Canada
Mentor: Dr. Atul Humar, Canada - Mentee: Minh-Tri Nguyen, Canada
Mentor: Dr. Steven Paraskevas, Canada
- Mentee: Markus Quante, United States
Mentor: Prof. Stefan Tullius, United States - Mentee: Paloma Riquelme, Germany
Mentor: Dr. James Alexander Hutchinson, Germany
- Mentee: Fadi Issa, United Kingdom
Mentor: Prof. Kathryn Wood
- Mentee: Sergio Duarte, United States
Mentor: Prof. Ana J. Coito, United States - Mentee: Lung-Yi Lee, United States
Mentor: Prof. Jon Odorico, United States - Mentee: Chang-Xian Li, China
Mentor: Prof. Nancy Kwan Man, China - Mentee: Shinichiro Yokota, United States
Mentor: Dr. Angus W. Thomson, United States
- Mentee: Carolina Moore, United States
Mentor: Dr. Joren Madsen, United States
- Mentee: Toshihiro Hirai, Japan
Mentor: Prof. Kazunari Tanabe, Japan - Mentee: Taigo Kato, Japan
Mentor: Dr. Masayoshi Okumi, Japan
- Mentee: Sylvain Le Pape, France
Mentor: Dr. Raphael Thullier, France - Mentee: Elodie Picarda, France
Mentor: Dr. Carole Guilonneau, France
- Mentee: Kylie Alexander, Australia
Mentor: Dr. Kelli MacDonald, Australia - Mentee: Kisha Sivanathan, Australia
Mentor: Prof. Patrick Coates, Australia
The Transplantation Society (TTS), along with the collaboration of National Societies acknowledge the contributions of basic science to the field of Transplantation. The International Basic Science Mentee-Mentor awards recognized the efforts of established basic scientists, who have advanced our understanding of transplant science/immunobiology and /or treatment of transplant recipients, and the mentorship of new young investigators who have the potential to contribute to the basic science of transplantation. The International Basic Science Mentee-Mentor award recipients for the BSM 2013 are listed below.
| Mentee | Mentor | Abstract Title |
| Abdelrarik, Heba, Egypt | Joosten, Irma | Human Platelet Lysate increases MSC proliferation on the expense of its Haematopoietic progenitor cell support |
| Candia, Enzo, Chile | Fierro, Alberto | Differential modulation of homing receptors in polyclonal human Treg generated ex vivo |
| Hock, Karin, Austria | Wekerle, Thomas | Donor CD4 T cells trigger costimulation blockade-resistant donor bone marrow rejection through bystander activation requiring interleukin 6 |
| Oberhuber, Rupert, Austria | Tullius, Stefan | Intracardiac CD11c+ dendritic cells trigger the more potent IL-17 mediated immune response after transplanting older cardiac allografts |
| Yang, Cheng, China | Yang, Bin | Serum Stabilized Naked Caspase-3 siRNA Protects Auto-transplant Kidneys in a Porcine Model |
| Zaitsu, Masaaki, United Kingdom | Wood, Kathryn | Prolongation of human skin allograft survival with FR104, an antagonistic antiCD28 monovalent Fab antibody |
| Mentee | Mentor | Abstract Title |
| Borkar, Minal, Canada | Tibbles, Lee Anne | BK polyoma virus epigenetically regulates transcription of epithelial markers in proximal tubular cells: Model for fibrosis in BK infected transplant recipients |
| White, Christopher, Canada | Freed, Darren H. | A donor whole blood-based perfusate provides superior preservation of myocardial function during ex vivo heart perfusion |
| Mentee | Mentor | Abstract Title |
| Sabet-Baktach, Manije, Germany | Geissler, Edward K. | Th2 Responses mediate Allograft Rejection in RORgammat and T-bet DoubleDeficiency in Mice |
| Mentee | Mentor | Abstract Title |
| Li, Chang Xian, China | Man, Kwan | The knockout of telomere-independent Rap1 attenuates liver graft injury by suppressing macrophage activation |
| Takaoka, Yuki, Taiwan | Nakano, Toshiaki | Autoimmunity vs. alloimmunity: its involvement in liver transplant tolerogenicity |
| Yoshida, Osamu, United States | Thomson, Angus | CD39 expression by hepatic myeloid dendritic cells attenuates their proinflammatory activity and liver transplant ischemia-reperfusion injury |
| Mentee | Mentor | Abstract Title |
| Dijke, Esme, Canada | West, Lori J. | CD25+FOXP3+ regulatory T cells (Tregs) isolated and expanded from pediatric thymus maintain stable phenotype and function under inflammatory conditions |
| Guihaire, Julien, Germany | Schrepfer, Sonja | Over-expression of S100A4 protein is T cells-mediated in a humanized model of chronic Obliterative Airway Disease |
| Pilat, Nina, Austria | Wekerle, Thomas | Mechanisms of Treg therapy in a murine mixed chimerism model |
| Mentee | Mentor | Abstract Title |
| Durand, Justine, France | Chiffoleau, Elise | Characterization of regulatory B cells in an allograft rodent model, able to transfer tolerance |
| Yap, Michelle, France | Degauque, Nicolas | An increase of highly differentiated TEMRA CD8 T cells with potent effector function in kidney transplant recipients with stable graft function revealed patients with at-risk of long-term graft function |
| Mentee | Mentor | Abstract Title |
| Abe, Tomoyuki, Japan | Tanaka, Yuka | The CD47-SIRP-α signaling blockade accelerates macrophage phagocytic activity against hepatocellular carcinoma even under immunosuppressive conditions |
| Cai, Songjie, Japan | Takahara, Shiro | Silencing CD40 gene to induce transplantation tolerance using a novel siRNA delivery system |
| Koshizuka, Yasuyuki, Japan | Yamashita, Kenichiro | Roles of CD40-CD40L costimulatory pathway in pancreatic islet transplantation |
| Mentee | Mentor | Abstract Title |
| Fang, Doreen, Australia | Dwyer, Karen | Follistatin reduces serum activin and attenuates renal ischemia reperfusion injury in mice |
| Habib, Miriam, Australia | Sharland, Alexandra | Ischaemia-reperfusion injury propagates tumour growth in a mouse model of hepatocellular carcinoma |
The Basic Science Mentee-Mentor award recognizes the efforts of established basic scientists, who have advanced our understanding of transplantation biology and the treatment of transplant recipients, as well as the mentorship of new young investigators who will advance transplantation in the future. We are pleased to announce the partnership between The Transplantation Society (TTS) and 7 National and International Transplantation Societies to support 27 Mentee-Mentor Award recipients for the 24th International Congress of The Transplantation Society. Congratulations to the 2012 Award Recipients!
| Mentee | Mentor | Abstract Title |
| Liu, Longshan, China | Wang, Changxi | Donor-Derived Mesenchymal Stem Cells Facilitate Minimization of Calcineurin Inhibitors in Kidney Transplant Patients and the Immune Profile Monitoring: A Clinical Pilot Study |
| Ortiz, Yaneth, Colombia | Garcia, Luis | Memory Phenotype and Polyfunctional T Cells in Kidney Transplant Patients |
| Qi, Xiang, China | Man, Kwan | Acute Phase Graft Injury Promotes Tumor Invasiveness through Down-Regulation of Glutathione Peroxidase 3 (GPx3) after Liver Transplantation |
| Skvorak, Kristen, United States | Strom, Stephen | Hepatocyte Transplantation Improves Blood and Brain Phenylalanine and Neurotransmitter Imbalances in a Mouse Model of Phenylketonuria (PKU) |
| Yang, Cheng, China | Yang, Bin | Naked Caspase-3 Small Interfering RNA (SiRNA) Was Effective in Cold Preservation of Isolated Porcine Kidneys, but Did not Protect Preserved Kidneys after Auto-Transplantation |
| Mentee | Mentor | Abstract Title |
| Ali, Jason, United Kingdom | Pettigrew, Gavin | Assessment of Longevity of the Direct and Indirect CD4 T Cell Allorecognition Response |
| Cole, Jennifer, United Kingdom | Pettigrew, Gavin | Memory CD4+ T Cells that Recognise Additional Mismatched Alloantigen Provide CD40-independent Help for Effector Anti-MHC Class I Alloantibody Responses |
| Issa, Fadi, United Kingdom | Wood, Kathryn | Homing of Therapeutic Human Regulatory T Cells to the Allograft Site Enhances Transplant Survival |
| Nova Lamperti, Estefania, United Kingdom | Hernandez-Fuentes, Maria | Higher IL10 Production by Transitional B Cells in Tolerant Kidney Transplant Recipients |
| Mentee | Mentor | Abstract Title |
| Jeyakanthan, Mylvaganam, Canada | West, Lori | T-Cell Dependency of T-Independent (TI) Antigens: Antibody Response to Blood Group A-Antigen Requires CD4 T-Cells and CD40/CD40L Interaction |
| Nguyen, Minh-Tri, Canada | Tchervenkov, Jean | Pre-Operative Regulatory T Cell Suppressive Function Correlates with Short-Term Graft Outcome after Kidney Transplantation |
| Srivastava, Vikas, Canada | Tibbles, Lee Anne | BK Polyoma Virus Induces Aberrant Methylation of Host Genome to Promote Epithelial Mesenchymal Transition and Fibrosis |
| Mentee | Mentor | Abstract Title |
| Heim, Christian, Germany | Ensminger, Stephan | PHD (Prolyl-Hydroxylase)-Inhibitor Activating Hypoxia-Inducible Transcription Factors (HIFs) Reduces Levels of Transplant Arteriosclerosis in a Murine Aortic Allograft Model |
| Hua, Xiaoqin, Germany | Schrepfer, Sonja | Immunobiology of SCNT Derived Embryonic Stem Cells: Pivotal Role of mtDNA in Rejection of Transplanted Stem Cells |
| Raschzok, Nathanael, Germany | Sauer, Igor M. | Silica-Based Micron-Sized Iron Oxide Particles for Detection and Loco-Regional Stimulation of Transplanted Liver Cells |
| Riquelme, Paloma, Germany | Hutchinson, James | Prolongation of Allograft Survival by Regulatory Macrophages in Mice Is iNOS-Dependent |
| von Websky, Martin, Germany | Schaefer, Nico | Reduced Expression of Mucosal Antimicrobial Peptides in the Small Intestine During Acute Rejection after Orthotopic Small Bowel Transplantation |
| Mentee | Mentor | Abstract Title |
| Petrelli, Alessandra, Italy | Battaglia, Manuela | Efficient Generation of Donor-Specific Tr1 CELLS from Patients on Hemodialysis |
| Mentee | Mentor | Abstract Title |
| Hotta, Ryuichi, Japan | Tanaka, Yuka | NK Cells Differentiated from Hematopoietic Stem Cells Exert Anti-HCC and Anti-HCV Activities Similar to Those of Peripheral Blood-Propagated NK Cells |
| Iwami, Daiki, Japan | Shirasugi, Nozomu | CD8+ Dendritic Cells with Regulatory Function Generated by Intratracheal Delivery of Alloantigen Induces Prolonged Cardiac Allograft Survival |
| Tasaki, Masayuki, United States | Yamada, Kazuhiko | Prevention of Early Development of Proteinuria by Rituximab in a Pig to Baboon Thymokidney Model Likely Associated with Modulating Podocyte Function in An SMPDL-3b-Dependent Manner |
| Mentee | Mentor | Abstract Title |
| Baulier, Edouard, France | Favreau, Frederic | Metabonomic Analysis of Perfusion Solution with NMR: A Potential Tool to Predict Graft Outcome in Deceased after Cardiac Arrest Donor Conditions |
| Mentee | Mentor | Abstract Title |
| Cunningham, Eithne, Australia | Bishop, G. Alex | Overcoming Naïve and Memory Immune Responses in a Mouse Skin Transplant Model Using High-Level Expression of Donor MHC Antigen in Recipient Livers |
| Hope, Christopher M., Australia | Carroll, Robert | Regulatory T Cells and the Development of Cancer Post Renal Transplantation |
| Hu, Min, Australia | O’Connell, Philip | A Key Role for Tregs in Renal Allograft Survival: Specific Deletion of Tregs in DEREG Mice Breaks Tolerance in Renal Transplants in the Murine DBA/2 to C57BL/6 Model |
| Villanueva, Jeanette, Australia | Grey, Shane | TRAF2 Governs the T Cell Alloimmune Response |
| Zammit, Nathan, Australia | Grey, Shane | Improved Survival Characteristics of An Inflammatory Suppressed Allograft |
The Transplantation Society (TTS), along with the collaboration of National Societies acknowledge the contributions of basic science to the field of Transplantation. The Basic Science Mentee/Mentor award recognizes the efforts of established basic scientists, who have advanced our understanding of transplant science/immunobiology and/or treatment of transplant recipients, and the mentorship of new young investigators who have the potential to contribute to the basic science of transplantation. The Mentee-Mentor Award recipients for the BSS 2011 are listed below.
| Mentee | Mentor | Abstract Title |
| Ata, Pinar, Turkey | Tittiz, M. Izzet | Flowcytometric detection of anti-AB antibody titers in blood group O renal recipients with blood group A2 donors |
| Hock, Karin, Austria | Wekerle, Thomas | Mechanistic analysis of costimulation blockade-resistant rejection of donor bone marrow triggered by donor T cells |
| Li, Changxian, People’s Republic of China | Man, Kwan | Aldose reductase accelerates small-for-size fatty liver graft injury |
| Liu, Quan, USA | Zheng, Xin Xiao | Vascularized Bone Marrow Transplantation: A New Approach to Induce Organ Transplant Tolerance |
| Moore, Carolina, Chile | Rosemblatt, Mario | Allogeneic Treg generated in vitro with retinoic acid and TGF-β control cytokine production and allograft rejection |
| Qi, Xiang, People’s Republic of China | Man, Kwan | Down-regulation of Glutathione peroxidase 3 (GPx3) by acute phase inflammation in small-for-size graft promotes tumor invasiveness after liver transplantation |
| Mentee | Mentor | Abstract Title |
| Bhatt, Sumantha, USA | Valujskikh, Anna | Neutralizing BAFF and APRIL in combination with anti-CD154 Ab treatment and CD8+ T cell depletion induces long term cardiac allograft survival in mice containing memory CD4+ T cells |
| Krzystyniak, Adam, USA | Witkowski, Piotr | Coating of human pancreatic islets with CD4+CD25+CD127- T regulatory cells inhibits rejection. A novel immunoprotective approach. |
| Zhang, Wensheng, USA | Zheng, Xin Xiao | CTA containing vascularized bone marrow offer the inherent potential for stable mixed chimerism and tolerance. |
| Mentee | Mentor | Abstract Title |
| Ellis, Jonathan, UK | Inston, Nicholas | Histone Deacetylase Inhibition reveals a potent immunosuppressant effect in an in vitro model of Transplantation |
| Mentee | Mentor | Abstract Title |
| Dijke, Esme, Canada | West, Lori | Impact of thymectomy and heart transplantation on CD4+FOXP3+ T-cell diversity in infants |
| Mentee | Mentor | Abstract Title |
| Grohnert, Anja, The Netherlands | Baan, Carla | IL-2-independent induction of novel CD4+CD25+CD127-FOXP3+ T cells by mesenchymal stem cells and natural regulatory T cells |
| Riquelme, Paloma, Germany | Geissler, Edward | Mouse Macrophages Driven to a Novel State of Activation Prolong Allograft Survival in Unconditioned, Non-immunosuppressed Recipients |
| Sabet-Baktach, Manije, Germany | Schlitt, Hans J. | Cutting-edge model to study the role of RORgT in T17-mediated allograft rejection |
| Schmuek, Michael, Germany | Volk, Hans-Dieter | Impaired IL2 signaling promotes CD4-mediated antiviral CD8+ T cell response |
| Mentee | Mentor | Abstract Title |
| Taflin, Cécile, France | Mooney, Nuala | Human microvascular endothelial cells induce polarization of Th-17 and regulatory-T cell sub-populations under inflammatory conditions |
| Mentee | Mentor | Abstract Title |
| Tazawa, Hirofumi, Japan | Ohdan, Hideki | Pivotal role of invariant NKT cell - B cell interaction in antibody production against transplant-associated carbohydrate epitopes |
| Mentee | Mentor | Abstract Title |
| Cunningham, Eithne, Australia | Bishop, Alex | High level expression of donor MHC in recipient liver promotes mouse skin transplant tolerance |
| Habib, Miriam, Australia | Sharland, Alexandra | Systemic overexpression of endogenous secretory RAGE attenuates renal ischaemia-reperfusion injury |
| Rogers, Natasha, Australia | Coates, Toby | Amelioration of renal ischemia-reperfusion injury by liposomal delivery of an NFBκB inhibitor to renal tubular epithelial and antigen presenting cells |
| MENTEE | ABSTRACT TITLE | MENTOR |
|---|---|---|
| Arthur Andakyan, United States | CD4CD25 Positive Mast Cells in Long-Term Surviving Grafts Followed by T-Regulatory Therapy: MC-regs? | Natalya Semiletova |
| Sonal Asthana, Canada | The Impact of Sirolimus Based Immunosuppression on Response to Anti-HCV Therapy After Liver Transplantation | Norman Kneteman |
| Agata Bartczak, Canada | FGL2 expression induces graft survival in the absence of immunosuppression. | Gary Levy |
| Lars Burdorf, United States | Pilot evaluation of anti-GP1b effects on platelet sequestration in an ex vivo xenogeneic pig liver perfusion model | Richard N. Pierson III |
| Hong Shiue Chou, United States | In Vivo Evidence: the Role of Complement Component 3 (C3) in Induction of Myeloid-Derived Suppressor Cells (MDSC) | Shiguang Qian |
| Pietro Cippà, Switzerland | Bcl-2 inhibition: a new concept to prevent solid allograft rejection | Thomas Fehr |
| Marcella Franquesa, Spain | Cell therapy using MSCs and BMDCs in rat kidney transplantation | Immaculada Herrero-Fresneda |
| Wei Geng, China | The potential role of early-phase graft injury in induction of late-phase chemoresistance after liver transplantation | Chung-Mau Lo |
| Ines Goncalves Harper, United Kingdom | A Novel Mechanism for Alloantibody Production. | Gavin Pettigrew |
| Aleishia Harris, United States | Modulation of Cellular MicroRNA by Latent Membrane Protein 1 of Epstein Barr Virus in B Cell Lymphomas Type: Oral Sessions Topic: 06. Complications / e. Malignancy Authors | Olivia Martinez |
| Min Hu, Australia | Allograft Tolerance in Mice with MGMT Chimeric Bone Marrow Engraftment | Stephen Alexander |
| Yanfei Huang, United States | Kidney-derived mesenchymal stem cells modulate dendritic and T cell function to inhibit alloimmune responses and prolong allograft survival | Karl Womer |
| Fadi Issa, United Kingdom | Regulatory T cell therapy prolongs human skin allograft survival in humanised mouse model | Kathryn Wood |
| Mylvaganam Jeyakanthan, Canada | Is blood group antigen expression on vascular endothelium required for B cell tolerance induction following ABO-incompatible transplant during immunological immaturity? | Lori West |
| Gillian Kinnear , United Kingdom | Blockade of OX40 costimulation reduces the alloreactive effector T cell pool and prevents CD8+ T cell mediated skin allograft rejection. | Nicholas Jones |
| Zhu Lan, Canada | Suppression of Antidonor Antibody Response by Soluble CD83 Prevents Chronic Renal Allograft Rejection | Hao Wang |
| Anlun Ma, Canada | Contribution of regulatory T cells combined with low-dose Sirolimus, but not Tacrolimus, to delay acute rejection of renal allografts in cynomolgus monkeys | Huifang Chen |
| Carolina Moore, Chile | Allogeneic Treg generated in vitro with retinoic acid and TGF-β control cytokine production and allograft rejection. | Mario Rosemblatt |
| Gerhard Mundinger, United States | Chronic rejection in a non-human primate model of facial composite tissue allotransplantation: clinical, pathological, and immunohistochemical characterization | Rolf Barth |
| Graeme O'Boyle, United Kingdom | A strategy to inhibit effector T cell infiltration of allograft tissues by stimulation of the chemokine receptor CXCR3 | John Kirby |
| Nina Pilat, Austria | Administration of polyclonal recipient Tregs leads to mixed chimerism, skin and heart graft tolerance without irradiation | Thomas Wekerle |
| Siddharth Rajakumar, Australia | CD73 deficiency and inhibition protect in kidney ischaemia reperfusion injury (IRI) | Karen Dwyer |
| Tim Searcy, Australia | Synergistic Immunomodulation by Immunosuppressive agentsand Human Mesenchymal Stem Cells on T-cell proliferation andDendritic cell maturation | Ravi Krishnan |
| Helena Smith-Hurst, Australia | A pathway for Human Islet Protease-Activated Receptors (PARs) in Tissue Factor mediated Immediate Blood Inflammatory Reaction. | Philip O'Connell |
| Özlem Tapirdamaz, Netherlands | Detailed kinetics of T-cells with direct allospecificity after liver transplantation: a novel assay | Jaap Kwekkeboom |
| Angela Tjon, Netherlands | In vivo immunosuppressive effects of intravenous immunoglobulin on innate and adaptive immune cells involved in allograft rejection | Jaap Kwekkeboom |
| Liang Wei, United States | Acute Rejection of Cardiac Allografts results in a Unique Signature of MicroRNAs | Sheri Krams |
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