This presentation provides a comprehensive overview of the historical development and evolution of histocompatibility science and its application in organ and bone marrow transplantation. It explores key milestones, technological advancements, and regional contributions from various parts of the world that have shaped current practices in immunogenetics and transplant compatibility assessment. The discussion highlights how these developments have influenced transplantation outcomes and continue to drive innovations in the field.
Learning Objectives
Describe the historical milestones in the development of histocompatibility science related to organ and bone marrow transplantation.
Identify key technological advancements that have shaped current immunogenetics practices.
Recognize the contributions and challenges faced by different global regions in advancing transplant compatibility assessment.
Discuss the role of professional associations and organizations in promoting histocompatibility research and collaboration.
Explain how historical developments and regional barriers have impacted transplantation outcomes.
Explore ongoing innovations and future directions in the field of histocompatibility and transplantation.
Estephan Arredondo Córdova, Spain Moderator TTS AHP Committee Co-Chair Bio
Technical Director,
BeCytes Biotechnologies (University of Barcelona)
Barcelona, Spain
Estephan Arredondo BS, Msc, is a biologist specialized in Organ, Tissues and Cell Donation from the University of Barcelona. He is currently Technical Director and Cofounder of Cytes Biotechnologies. He also acts as co-chair at the Allied Health Group of the Transplantation Society.
His studies are based on how to develop networks to procure human tissue for research and isolation of human liver cells. He has been involved in several European projects related to international cooperation in organ donation such as the Black Sea Area andMiddle East.
Thais Freesz, Brazil Moderator TTS AHP Committee Member / ABHI Member
Sandra Tafulo, PhD, is the EFI laboratory Director in Portuguese Blood and Transplantation Institute in Porto, Portugal.
Dra. Sandra is Councillor of the Executive Committee of European Federation for Immunogenetics (EFI), Inspector and Commissioner for EFI Accreditation Committee, member of International Committee of American Society for Histocompatibility and Immunogenetics (ASHI) and Board of Directors member of ASHI. She is also a member of the research unit UMIB – group of nephrology, dialysis and transplantation at the Institute of Biomedical Sciences Abel Salazar – Porto University, member of expert group in Portuguese KPD and member of Portuguese Transplantation and Immunogenetic group of Portuguese Transplantation Society (SPT).
Head, Histocompatibility and Immunogenetics Laboratory
Nephrology and Transplantation Department Hospital General San Juan de Dios, Guatemala City
Karla Escobar-Castro, QB, PhD, is Director of the Clinical Laboratory at the Biomedical Research Center and faculty member at the Faculty of Medical Sciences, Universidad de San Carlos de Guatemala. She leads the Immunogenetics and Transplant Research Program at Hospital General San Juan de Dios, focusing on HLA diversity, autoimmune diseases, and pharmacogenetics in kidney transplantation. Dr. Escobar-Castro Full Member of the Academy of Medical, Physical and Natural Sciences of Guatemala, a member of ASHI, EFI, and TTSS, and author of several publications on HLA and transplantation immunogenetics.Portuguese Transplantation Society (SPT).
Analytical Chemist and discipline Leader
Universidad Autónoma de Nuevo León (UANL), Monterrey
Dr. Jorge Solis-Estrada is a member of the Molecular Medicine and Histocompatibility Laboratory, Hematology Service at Hospital Universitario Dr. José Eleuterio González. He serves as Discipline Leader for Molecular Biology, Histocompatibility, and Genetics accredited by EMA (CL-011), EFI (99-MX-002.998) and FACT-JACIE. Since 2023, he has been an invited professor in the master’s program in Hematology Laboratory.