13th International Transplant Infectious Disease Conference
Cutting Edge Topics in Transplant INfectious Disease for the Transplant Clinician
November 17-18, 2021 • 07:00 to 11:00 ET (See below for your local time)
Overview
The number of solid organ transplants and stem cell transplant procedures continue to increase worldwide and graft survival and mortality has been improved through prevention of rejection by immunosuppression therapies. As a consequence of these immunosuppressive therapies, infections caused by both conventional and opportunistic pathogens continue to be prevalent.
The susceptibility of transplant recipients to infection is related to multiple factors, including pre-transplant characteristics, type of transplanted organ, intraoperative characteristics and other post-transplant factors. However, there have been recent laboratory advances that allow for improved risk prediction, and development of novel vaccines that prevent infection. The epidemiology, prevention and treatment of infection in transplant recipients remains an important topic, and one that requires continual review to best impact patient care. This educational symposium will update participants on the epidemiology, prevention and treatment of infection among solid organ and stem cell transplant patients. Key areas of focus include COVID-19, antimicrobial stewardship, evolving donor risk, emerging pathogens and top papers in transplant and cancer infectious diseases.
Learning Objectives
To understand risk assessment for infection in organ transplant recipients throughout the world
To appreciate the management of complicated cases in solid organ transplant recipients
To provide updates on currents strategies for antimicrobial stewardship in solid organ and stem cell transplant patients
To understand the current epidemiology, prevention and management of transplant patients with COVID-19
Ricardo La Hoz
Associate Professor of Internal Medicine
Division of Infectious Diseases and Geographic Medicine
UT Southwestern Medical Center
Dr. La Hoz received his medical degree from the Universidad Peruana Cayetano
Heredia (UPCH) in Lima, Peru. He completed his Internal Medicine Residency and
Infectious Diseases Fellowship at the University of Alabama at Birmingham
(UAB).
He currently serves as an Associate Professor of Internal Medicine in the Division
of Infectious Diseases and Geographic Medicine. His activities in the American
Society of Transplantation led to his election as an Executive Committee Member
of the Infectious Diseases Community of Practice and served his term from 2016
to 2018. In 2017 he became a Fellow of the American Society of Transplantation
(FAST) due to his commitment to the field of transplantation and outstanding
service to the society and in 2019 a Fellow of the Infectious Diseases Society of
America (FIDSA). Additionally, he has been an At Large Member of the Organ
Procurement Transplantation Network/ United Network of Organ Sharing Ad Hoc
Disease Transmission Advisory Committee since 2016 and currently serves as
the Chair. In 2019 he joined the Editorial Board of the American Journal of
Tranplantation as an Associate Editor.
Francisco López-Medrano, MD PhD MSc
Unit of Infectious Diseases
University Hospital 12 de Octubre
School of Medicine, Universidad Complutense de Madrid
Degree in Medicine and Surgery – 1995 – Faculty of Medicine, Univesidad Autónoma de Madrid, Spain. Specialist in Internal Medicine – 2002 - University Hospital 12 de Octubre, Madrid, Spain. Master in Infectious Diseases – 2004 – School of Medicine – Universidad Complutense de Madrid, Spain. PhD in Medicine – Respiratory virus in solid organ transplant recipients – 2006 – Faculty of Medicine – Universidad Autónoma de Madrid, Spain. Member of the staff of the Unit of Infectious Diseases – University Hospital 12 de Octubre, Madrid, Spain – 2004 to present. Assistant Professor in Medicine – Department of Medicine – Faculty of Medicine – Universidad Complutense de Madrid, Spain – 2005 to present. Accredited for Associate Professor by ANECA (Ministry of Science, Innovation and Universities, Spain) – November 2018. Member of the Institute for Biomedical Investigation i+12 – Foundation for Investigation – University Hospital 12 de Octubre, Madrid, Spain. More than 245 articles published in national and international journals in the field of Infectious Diseases.
Yellow fever and beyond: South American Perspective
Alice Song
Infectious Diseases Physician
Hospital Clinicas, University of São Paulo
Alice Song, MD, PhD, is the Infectious Diseases Physician at the Liver and Digestive Organ Transplant Unit at Hospital das Clinicas, University of São Paulo. She has research grants in the field of Infections in Liver Transplantation from the Sao Paulo Research Foundation (FAPESP), and has done Post-Doctorate Fellowships at Paul Brousse Hospital in Villejuif, France, and Columbia University at New York, USA.
Session 2 - Predicting Infections in Transplant
Moderators: Jose Maria Aguado and Alessandra Mularoni
Kim Hanson
Professor of Medicine and Pathology
University of Utah and ARUP Laboratories
Dr. Kimberly Hanson is a Professor of Medicine and Pathology at the University of Utah. Administratively, Dr. Hanson serves as the Director of the Immuncompromised Host Infectious Diseases Service and is Section Chief for Clinical Microbiology. She maintains an active research program that is focused on the development and validation of novel, cost-effective diagnostic tests with a focus on opportunistic infections.
Associate Professor of Infectious Diseases, Infectious Diseases Consultant IRCCS Policlinico Sant’Orsola, Alma Mater Studiorum University of Bologna
Maddalena Giannella graduated from University “La Sapienza”, Rome-Italy in 2003, and went on to complete her residency training in Internal Medicine at the same university in 2008. In 2012, he received PhD degree in Clinical Microbiology from University “Complutense”, Madrid-Spain. From 2008 to 2012, she worked as clinical researcher and infectious diseases consultant at the Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid-Spain. Since 2013, she has been working as infectious diseases consultant and member of the antimicrobial stewardship team at the IRCCS Policlinico di Sant’Orsola, Bologna-Italy. From 2015 to 2018, she served as senior researcher at the Department of Medical and Surgical Sciences, University Alma Mater Studiorum of Bologna-Italy. Since 2018, she is associate professor of Infectious Diseases at the same university. Since 2016, she is member of the Executive Committee of the European Study Group of Bloodstream infection Endocarditis and Sepsis (ESGBIES) of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID). She is associate editor of Transplant International, the official journal of the European Society for Organ Transplantation (ESOT). She is author of 150 articles published on national and international peer reviewed journals, H-index 35 (Scopus source). The main research fields include antibiotic resistant infections, infections in solid organ transplant recipients, sepsis and bloodstream infections.
Associate Professor, Vaccine and Infectious Disease Division Fred Hutchinson Cancer Research Center
Dr. Steven Pergam is an Associate Member in the Clinical Research and Vaccine and Infectious Diseases Division of the Fred Hutchinson Cancer Research Center; Associate Professor in the Division of Allergy & Infectious Diseases at the University of Washington; and the Director of Infection Prevention at the Seattle Cancer Care Alliance, in Seattle, WA. His current research interest focuses on the epidemiology of major transplant pathogens and on the development of novel prevention strategies for community and healthcare-associated infections in cancer and hematopoietic cell transplant patients.
Ligia Pierrotti
ID physician at the Kidney Transplant Unit and leader member of Infectious Diseases on Immunocompromised Host Group at the Hospital das Clínicas, School of Medicine of the University of São Paulo (HCFMUSP)
Lígia Camera Pierrotti, MD, PhD, is an ID physician graduated in State University of Campinas (Unicamp) in 1993. M.Sc and Ph.D. in Infectious Diseases at University of São Paulo, Brazil, in 2004. She is currently assistant physician at the Kidney Transplant Unit and leader member of Infectious Diseases on Immunocompromised Host Group at the Hospital das Clínicas, School of Medicine of the University of São Paulo (HCFMUSP). Ligia Pierrotti is Co-Chair of ID Committee of the Brazilian Association of Organ Transplantation (ABTO) and is permanent member of the Brazilian Standing Committee on Biosurveillance. Dra. Lígia is a member of Member ID Committee of National Transplant Program coordinated by Brazilian Ministry of Health and a member of TID/TTS. Her research has been directed towards epidemiology, prevention and management of infections in immunocompromised host, particularly solid organ transplant. Dra. Lígia is currently Associate Editor of Transplant International Journal.
Rachel Miller, MD, FIDSA, FAST
Professor of Medicine, Duke University
Durham, NC
Dr. Miller has practiced Transplant ID for 25 years, first as the
founder of the Transplant ID service at the Univ of Iowa (1996-2016), then joined
the Transplant ID faculty at Duke Univ (2016-2021). At Duke, she provides clinical
care for transplant recipients and is involved in several transplant associated
clinical research studies, clinical operations leadership, and fellow /faculty
mentoring. ID Week Program Committee for IDSA from 2017-2019. Four years as
an Associate Editor for the American Journal of Transplantation. Sustained
involvement in scholarly projects and national committee work though the AST,
IDSA and UNOS, largely related to the field of organ transplantation. Dr. Miller has
consistently served as a lecturer at national & regional meetings. Authored over 40
articles, book chapters, and other publications.
Day 2: Thursday, November 18
Thursday, November 18, 2021, 7:00 AM
(Local time in Montreal) Local time (Corresponding local time at your current location)
Elisabeth Coll Torres, MD PhD
Head of Medical Department,
Spanish Transplant Organization
Madrid, Spain
Elisabeth Coll Torres, MD PhD, is specialist in preventive medicine and public health. She works since 2006 in the Spanish National Transplant Organization (ONT) and named Head of the Medical Department in 2017. She is also Associate Professor for Biostatistics in the Faculty of Medicine of the Alfonso X University, Madrid. She has a large experience in training and research, especially in the development of different programs focused on donation and transplantation activity, such the design and implementation of the Spanish action plan to promote donation after circulatory death or the management and analysis of the Lung Transplantation Spanish Registry. During her career she has participated as an expert in several WHO Regional Consultations and in European Commission working groups. She is also author of many articles and chapters of books on donation and transplantation.
Robin Avery
Professor of Medicine, Division of Infectious Diseases, Johns Hopkins University
Robin Avery MD, FIDSA, FAST is Professor of Medicine (Infectious Diseases) at Johns Hopkins. After ID fellowship at Massachusetts General Hospital, she was an attending physician at Cleveland Clinic from 1993-2012, and at Johns Hopkins from 2012 onward. A past chair of the AST ID Community of Practice, she has served on committees for ISHLT, AST, IDSA, and ICHS. Her research involves viral infections, novel therapies for CMV, hypogammaglobulinemia, infections in incompatible kidney transplant recipients, and strategies for safer living after transplant. In 2017 she was named Best Consulting Physician at Johns Hopkins. In 2020-21, she has been active in COVID-19 clinical care for transplant and oncology patients, and COVID-19 epidemiologic studies and clinical trials.
Raymund Razonable
Professor of Medicine, Program Director and Vice Chair, Division of Infectious Diseases, Mayo Clinic
Raymund R. Razonable, MD, is Professor of Medicine and Distinguished Clinician at the Mayo Clinic College of Medicine and Science in Rochester, Minnesota. He serves as the Vice Chair of the Division of Infectious Diseases, and Program Director of the Infectious Diseases Fellowship Training Programs at the Mayo Clinic.
Dr Razonable’s clinical, educational and research interests include infections related to organ transplants. He has authored more than 240 peer-reviewed original and review articles, more than 30 book chapters, and more than 200 abstracts on these topics. He is a sought-after speaker at national and international meetings. Dr Razonable is associate editor of Transplant Infectious Diseases and serves on the editorial boards of several scientific journals.
A recipient of numerous awards and honors throughout his career, Dr Razonable was inducted as a Fellow of the Infectious Diseases Society of America, and Fellow of the American Society of Transplantation.
Stephanie Pouch
Infectious Diseases
Emory University School of Medicine
Dr. Pouch received her MD from Temple University School of Medicine in 2007. She completed her internship and residency in internal medicine at the University of Chicago, served as a chief resident at the John H. Stroger, Jr. Hospital of Cook County, and completed fellowship training in infectious diseases at Columbia University Medical Center. While at Columbia, Dr. Pouch obtained a Master of Science in Biostatistics at the Mailman School of Public Health. She joined the faculty at Emory University as an Assistant Professor of Medicine in the Division of Infectious Diseases in 2017.
Dr. Pouch’s clinical and research interests relate to infectious complications of solid organ and stem cell transplantation, with a primary research emphasis on multidrug-resistant Gram-negative infections in transplant recipients. She is an active member of the American Society of Transplantation, where she serves as Past Chair of the Infectious Disease Community of Practice’s Multidrug-Resistant Organisms Workgroup, as well as the International Society for Heart & Lung Transplantation and The Transplantation Society.
Session 2 - Antimicrobial Stewardship
Moderators: John Baddley and Siriorn Watcharananan
Jonathan Hand
Medical Director, Transplant Infectious Diseases
Medical Director, Antimicrobial Stewardship Program
Ochsner Medical Center, New Orleans, LA, USA
Dr. Jonathan Hand earned his medical degree from Louisiana State University School of Medicine, New Orleans, and completed his internship, residency, and infectious diseases fellowship at the Icahn School of Medicine at Mount Sinai in New York. He currently serves as Medical Director of the Transplant Infectious Diseases Program and Medical Director of the Antimicrobial Stewardship Program at Ochsner Medical Center in New Orleans, LA. He is a Fellow of The American Society of Transplantation and Fellow of The Infectious Diseases Society of America and has held various leadership roles within national and international transplant societies and serves as the Associate Medical Director of the Louisiana Organ Procurement Agency and co-chair of their advisory board. His practice and research interests include infectious complications of transplant recipients and antimicrobial stewardship and is a member of the Immunocompromised Host Working Group within the Antibacterial Resistance Leadership Group (ARLG)
Monica Slavin
Director, Department of Infectious Diseases, Peter MacCallum Cancer Centre Melbourne, Australia
Professor Monica Slavin leads the National Health and Medical Research Council (NHMRC) funded Centre of Research Excellence in Infections in Cancer at Sir Peter MacCallum Department of Oncology, University of Melbourne. She is Director of the Department of Infectious Diseases at Peter MacCallum Cancer Centre and of the Immunocompromised Host Infection Service at Royal Melbourne Hospital in Melbourne, Australia. She is Professor in the Department of Medicine, University of Melbourne and is an NHMRC Leadership fellow. Prof Slavin is immediate past- President of the International Immunocompromised Host Society and secretary of the Immunocompromised Host working group of ESCMID. Her research focuses on prevention, diagnosis and management of infections in the immunocompromised host with a particular interest in invasive fungal infection.
Professor of Infectious Diseases, University of Insubria, Director
Infectious and Tropical Diseases Unit Asst-Sette Laghi
Paolo Grossi is Professor of Infectious Diseases at the University of Insubria in
Varese, Italy. Since the year 2000 he is professor of Infectious Diseases and
director of the Infectious and Tropical diseases unit of ASST-Sette Laghi. The
main research interest is in the field of infectious complications in transplant
recipients. Starting from 1999 he is the advisor for all infectious diseases
related problems at the Italian National Centre for Transplantation in Italy
and covers the role of “second opinion” for all organ donors with potentially
transmissible infectious diseases. He is currently the chair of the steering
committee of the ESCMID Study Group on infections in Immunocompromised
Host (ESGICH).
Pharmacological considerations - drug interactions, allergies
Lee Puay Hoon
Senior Principal Clinical Pharmacist
Singapore General Hospital
Lee Puay Hoon Pharm D, BCPS, is a senior principal clinical pharmacist at Singapore General Hospital, in-charge of pharmacy clinical service for solid organ transplant, nephrology and inpatients at Singapore General Hospital. Dr Lee is a member of Singapore Society of Transplantation, Singapore Society of Nephrology.
She is a non-physician faculty member of the SingHealth Renal Medicine senior residency program, clinical preceptor for National University of Singapore PharmD program and National pharmacy residency program.
Associate professor, Infectious Diseases Service and Transplantation Center,
Lausanne University Hospital
Oriol Manuel, MD works at the Lausanne University Hospital, Switzerland, as
transplant infectious diseases specialist and clinical research scientist. His main
interest is in the area of clinical research involving viral infections in transplant
recipients. He is interested in the epidemiology and preventive strategies for
cytomegalovirus (CMV) disease and influenza in the transplant population. He is
associate professor at the University of Lausanne. He is also member of the Scientific
Committee of the Swiss Transplant Cohort Study (STCS), and Associate Editor of the
!American Journal of Transplantation and Transplant International.
Professor of Medicine, Perelman School of Medicine; Director Transplant Infectious Diseases; Program Director Infectious Diseases Fellowship, University of Pennsylvania
Emily Blumberg, MD is a Professor of Medicine at the Perelman School of Medicine at the University of Pennsylvania, where she is the Director of Transplant Infectious Diseases and the Program Director of the Infectious Diseases Fellowship program. Dr. Blumberg's academic interests are focused on infectious disease complications in transplant recipients and candidates. She is especially interested in donor derived infections and viral infections, including HIV, HCV, CMV, and now COVID-19. She is a Deputy Editor for the American Journal of Transplantation and a Section Editor for UpToDate. A member of the AST since 1999, she served as its President from 2019-2020 and currently leads its COVID-19 task force. She is a former Chair of the UNOS Disease Transmission and Advisory Committee, former Vice-Chair of the HHS Advisory Committee on Blood and Tissue Safety and Availability, and former member of the Gift of Life (Philadelphia) Medical Advisory Board and current member of the UNOS MPSC.
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