Title: Use of a Novel Anti-Humoral Therapy - IdeS – as a Desensitization Strategy in Xenotransplantation
Mentor: Andrew B. Adams, MD PhD
Institution: University of Minnesota
Summary: Dr. Matar’s research will focus on strategies to prevent antibody-mediated rejection in xenotransplantation. Specifically, Dr. Matar will study the efficacy of IdeS, an antibody-degrading enzyme with specificity for IgG, as a desensitization strategy in a pig to primate model of kidney xenotransplantation. Dr. Matar will be mentored by Dr. Andrew Adams, MD PhD, currently a Professor of Surgery and chief of the Division of Transplantation at the University of Minnesota.