Transplantation - February 2022 Issue

JUST RELEASED - TRANSPLANTATION - FEBRUARY ISSUE

This month brings a focus on how and where we will get progress in clinical practice with '-omics', big data analysis and linkages. There is also a reminder to understand the fragility of the results we rely upon - robust or p values gone in a puff of wind. A beautiful review of the macrophage in transplantation will be important reading for most of us. The focus in liver transplantation remains IRI and the DCD donor, with concomitant interest in Biliary strictures. Angiotensi receptor antibodies are carefully analyzed in a single center heart transplant study. Long term use of Everolimus is analyzed in kidney transplant recipients, while an analysis of eGFR calculators does not inspire us to rely upon any of the 63 equations examined.

CLICK HERE TO ACCESS THIS ISSUE


Professor Mehmet Haberal awarded the Ihsan Doğramacı Family Health Foundation Prize by the World Health Organization (WHO)

Professor Mehmet Haberal
TTS Immediate Past President

TTS would like to congratulate Prof. Haberal for this well-deserved award recognizing his vast contributions to family health.

Professor Ihsan Doğramacı, established the Ihsan Doğramacı Family Health Foundation in 1980 to promote and raise the standard of family health by awarding a prize every two years to individuals who have given distinguished service in the field of family health. Prof. Haberal will be presented with his award on May 27 in a special ceremony during the WHO World Health Assembly.

IPTA 2022 Virtual - Accessible to Everyone!

State-of-the-Art Speakers

Special Activities for Trainees and Allied Health Professionals

More information will be available on the congress website shortly.

Trainees / Fellows / Students

Saturday, March 26 | 13:00 EST
Mentorship can be a big asset in your career path and we are bringing mentors to you! Meet them in small virtual breakout groups, ask your questions, or simply listen to their invaluable advice. Inspiration and motivation guaranteed!

Allied Health and Nursing Professionals

Saturday, March 26 | 12:30 EST
IPTA’s Allied Health Committee is presenting a very timely session on Navigating Moral Distress and Compassion Fatigue. You will leave equipped with tools and strategies to manage these stressors efficiently.

Registration Highlights

Registration for the virtual congress is open and fees are very affordable in order to make this virtual event accessible to everyone.

Special Promotion for Non-Members:

This is a great time for non-members of ITPA to join by registering with the SPECIAL PACKAGE which includes the REGISTRATION FEES PLUS 1-YEAR IPTA MEMBERSHIP (for 2022).

Member benefits include a subscription to Pediatric Transplantation which is published 8 times per year (available online only). View all IPTA Membership Benefits here:


TTS 2022 - Argentina - September 10-14

Submit an abstract to contribute to the scientific success of our Congress!

We invite all our members and the transplant community as a whole to present their latest research at the Congress. Choose among many submission topics and we are also offering abstract-based awards!

Accepted abstracts will be published in an online supplement of Transplantation.

( https://tts2022.org/program/call-for-abstracts )

2022 Mentee-Mentor Awards

The International Transplantation Science Mentee-Mentor Awards are designed to encourage dialogue and interactions between trainees and established investigators, and provide financial support for their joint participation in the Congress.

Transplantation
Week's Most Downloaded Paper

Transplantation Direct
Week's Most Downloaded Paper


Hot Off The Press

«HOT OFF THE PRESS» 
RECENT PUBLICATIONS IDENTIFIED
BY TTS EDUCATION COMMITTEE ON COVID-19

Selected Publications by TTS Education Committee. This week's selection made by Dr. Enver Akalin.

Cross-reactive memory T cells associate with protection against SARS-CoV-2 infection in COVID-19 contacts

Rhia Kundu et al.
Nat Commun. 2022 Jan 10;13(1):80. doi: 10.1038/s41467-021-27674-x.PMID: 35013199

This study assessed 52 COVID-19 household contacts to capture immune responses at the earliest timepoints after SARS-CoV2 exposure. Using a dual cytokine FLISpot assay on peripheral blood mononuclear cells, the frequency of T cells specific for spike, nucleocapsid, membrane, envelope and ORF1 SARS-CoV-2 epitopes that cross-react with human endemic coronaviruses were analyzed. Higher frequencies of cross-reactive (p = 0.0139), and nucleocapsid-specific (p = 0.0355) IL-2-secreting memory T cells in contacts who remained PCR-negative despite exposure (n = 26), when compared with those who convert to PCR-positive (n = 26); no significant difference in the frequency of responses to spike is observed, hinting at a limited protective function of spike-cross-reactive T cells. In summary, pre-existing non-spike cross-reactive memory T cells protecting SARS-CoV-2-naïve contacts from infection, thereby supporting the inclusion of non-spike antigens in second-generation vaccines.

T-cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals

Cell, January 2022 DOI: https://doi.org/10.1016/j.cell.2022.01.029

The SARS-CoV-2 Omicron variant (B.1.1.529) contains mutations that mediate escape from antibody responses, although the extent to which these substitutions in spike and non-spike proteins affect T-cell recognition is unknown. This study shows that T-cell responses in individuals with prior infection, vaccination, both prior infection and vaccination, and boosted vaccination are largely preserved to Omicron spike and non-spike proteins. However, a subset of individuals (∼21%) with a >50% reduction in T-cell reactivity to the Omicron spike were indetified. Evaluation of functional CD4+ and CD8+ memory T cell responses confirmed these findings and reveal that reduced recognition to Omicron spike is primarily observed within the CD8+ T cell compartment potentially due to escape from HLA binding. Booster vaccination enhanced T-cell responses to Omicron spike. In contrast to neutralizing immunity, these findings suggest preservation of T-cell responses to the Omicron variant, although with reduced reactivity in some individuals.


Deadline extended to February 14 - TTS Call for Nominations for Leadership

2022 TTS Call for Nominations for Officers and Councilors

In 2022, two Officer positions will be vacated and 5 of the 12 Councilors-at-large representing the Regions will be changing. The elections will take place early in 2022 and those elected will assume their new roles starting at the 2022 TTS Congress in Buenos Aires.

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Members can access the online nominating form at www.tts.org/nominations. Since each nominee must have his or her form signed by three supporting members (including him/herself), the online process allows for efficient and rapid circulation.

THE NOMINATION DEADLINE HAS BEEN EXTENDED TO FEBRUARY 20, 2022.

Please note:

  • As successive presidents may not be from the same Region, members from the Middle East / Africa region who would have otherwise been eligible to become President-Elect are not eligible in these elections.
  • Only members who have served a full term on Council and have paid their dues are eligible for the Officer positions (President-Elect and Treasurer).
  • Only full members who have paid these dues are eligible to be nominated for Council.
  • Only full members who have paid their dues may nominate and/or vote.

For more information on elections, visit the TTS website and consult the By-Laws in the “About” section.

Nominations are being sought for these positions

Officer Positions:

  • President-Elect
  • Treasurer

TTS Regions:

  • Europe (1)
  • Latin America (1)
  • Middle East / Africa (1)
  • North America (1)
  • Oceania (1)

CLICK HERE TO ACCESS THE NOMINATING FORM (requires login)

Alternatively - Click here to download Forms as a PDF

TTS Call for Award Nominations

2022 Awards Call for Nominations

Medawar Prize

Call for nominations

Recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation.

The Medawar Prize

The Medawar Prize, named after Society co-founder Sir Peter Medawar, is recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation. The Medawar Prize has been awarded at each of our Society's biennial Congresses since 1990.

The award recognizes the outstanding investigators whose contributions have had such a profound influence on the field of organ transplantation. The Medawar Prize is universally considered to be commensurate with the most outstanding world prizes for scientific achievement.

Application Extended Deadline

May 1, 2022

Eligibility to Award

All full members in good standing will be eligible to be nominated for this award.

Frequency of Award

The Award will be given at each of the TTS Biennial congresses.

Selection of the Recipient

The selection committee consists of the previous five Past Presidents of The Transplantation Society.

Monetary Award

The monetary award will be $25,000.

Past Medawar Laureates

2020
2018
2016
2014
2012
2010
2008
2006
2004
2002
2000
1998
1996
1994
1992
1990
Starzl Prize

CALL FOR NOMINATIONS

Application Deadline

May 1, 2022

Supported by

Early in his career, Dr. Starzl recognized the importance of deceased donation. He pioneered many facets of transplantation, including immunosuppressive drug development, organ preservation, tissue matching, surgical transplant technology, and developed the team approach to organ transplantation; thus paving the way for the success and acceptance of heart, lung, pancreas, intestinal, liver, and kidney transplantation. The international impact of the fruits of seven decades of commitment to transplantation is shown by estimates of over 600 000 Americans and millions of patients around the world that have received a life-saving organ transplantation. He was also credited as having trained over 1,000 medical and surgical transplant specialists over his 50 years in clinical medicine, many of whom have gone on to successfully develop their own transplant

Eligibility to Award

All full members in good standing will be eligible to be nominated for this award.

Frequency of Award

The Award will be given at each of the TTS Biennial congresses.

Selection of the Recipient

The Chair of the Selection Committee will be the then current TTS President, who will choose a selection committee of 3 among the Council members.

Monetary Award

The monetary award will be $10,000.

Previous Winners

2020

Recognition Awards

Call for nominations

These awards recognize individuals who have made a major international impact in the field of transplantation. The awards are given out at each International Congress of The Transplantation Society and carry a monetary award of USD $2,000 each.

Available Awards for 2022

Outstanding Achievement Transplantation Science (Basic)

Outstanding Achievement in Transplantation Science (Clinical)

Outstanding Achievement in Transplantation Science (Developing Country)

Mentorship or Education and Training in Transplantation


Select a year to view past recipient details

2020
2018
2016
2014
2012
2010
2008
2006
WIT Awards

WIT Awards

The Women in Transplantation Steering Committee have created the Woman Leader in Transplantation Award to recognize a woman who has helped further the field of transplantation through research, policies, leadership, initiatives or other regarded contributions. The Unsung Hero Award will be presented to one woman who has had an extraordinary impact in transplantation through community service, volunteering, mentorship or other community based activity. Both Awards are presented during the presidential address at the TTS International Congress.

ELIGIBILITY REQUIREMENTS:
NOMINATION PACKAGE MUST INCLUDE:
AWARD DETAILS
INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE-MENTOR AWARDS

THE TRANSPLANTATION SOCIETY (TTS), ALONG WITH COLLABORATION OF NATIONAL AND INTERNATIONAL SOCIETIES, ACKNOWLEDGES THE CONTRIBUTION OF BASIC SCIENCE TO THE FIELD OF TRANSPLANTATION.

THE INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE-MENTOR AWARDS FOR THE 29TH INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY (TTS 2022) – BUENOS AIRES, ARGENTINA, SEPTEMBER 10-14, 2022.

The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Awards to recognize the efforts of scientists who have advanced our understanding of transplantation science and fostered the development of the young investigators who will be the future leaders in our field.

The application will open in January 2022. Deadline for submission is April 10, 2022.

Click here for more details

Women in Transplantation at World Congress of Nephrology 2022

Women in Transplantation are delighted to announce a Scientific Symposium and Topical Networking Sessions as part of ISN-WCN 2022 Congress.

WCN’22: Virtual, In-Person, and On-Demand

Registrations to WCN’22 is still open, join the world’s leading experts in kidney health, to exchange the latest science and clinical applications to improve kidney care and prevent kidney disease worldwide. Promoting inclusivity and equitable access, WCN’22 organizers offer different ways to access the congress, including the registration to the Pre-congress courses only or the complimentary registration to the Open-Access Sessions.
Complimentary Access to All WIT Members

TOPICAL NETWORKING SESSIONS

Thursday, February 24, 2022 - 7:00 PM
(Malaysian Time MYT)
Local time
(Corresponding local time at your current location)
Complimentary Access to All WIT Members

TOPICAL NETWORKING SESSIONS

Friday, February 25, 2022 - 10:30 PM
(Malaysian Time MYT)
Local time
(Corresponding local time at your current location)
Only Accessible if Registered for the Congress

Women in Transplantation SYMPOSIUM

Saturday, February 26, 2022 - 3:00 PM
(Malaysian Time MYT)
Local time
(Corresponding local time at your current location)

Critical Care and Organ Donation in India - Full Series Recordings Available


A Collaborative Webinar Series between The Transplantation Society, the Indian Society of Critical Care Medicine, the Indian Society of Transplantation, and the International Society for Organ Donation and Procurement.



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Contact

Staff Directory
+1-514-874-1717
info@tts.org

Address

The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada