The team's process was able to take lungs from people with type A blood and essentially convert them into universal type O lungs.
Researchers in Canada say they’ve found a way to help people who otherwise would be left languishing on the organ transplant list. In new research this week, they detail converting lungs from people with type A blood into lungs that could be donated to anyone, without heavily damaging them or causing acute rejection. Assuming the team’s work is further validated and tested to be safe, it may someday expand the pool of universal donor lungs.
The man with a pig's heart - The work of many scientists over decades has led to this extraordinary medical breakthrough...
In 2022, two Officer positions and 5 of the 12 Councilors-at-large representing the Regions will be completing their terms. The elections will take place early in 2022 and those elected will assume their new roles starting at the 2022 TTS Congress in Buenos Aires./p>
Members can access the online nominating form at www.tts.org/nominations. Since each nominee must have his or her form signed by three supporting members (including him/herself), the online process allows for efficient and rapid circulation.
For more information on elections, visit the TTS website and consult the By-Laws in the “About” section.
Recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation.
THE INTERNATIONAL TRANSPLANTATION SCIENCE MENTEE-MENTOR AWARDS FOR THE 29TH INTERNATIONAL CONGRESS OF THE TRANSPLANTATION SOCIETY (TTS 2022) – BUENOS AIRES, ARGENTINA, SEPTEMBER 10-14, 2022.
The Transplantation Society celebrates the contributions of basic science to the field of transplantation with the International Transplantation Science Mentee-Mentor Awards to recognize the efforts of scientists who have advanced our understanding of transplantation science and fostered the development of the young investigators who will be the future leaders in our field.
The application will open in January 2022. Deadline for submission is April 10, 2022.Click here for more details
This study investigated immune signatures from the peripheral blood during and after COVID-19 infection of 64 kidney transplant recipients; 31 acute cases (< 4 weeks from diagnosis) and 33 post-acute cases (>4 weeks). Functional enrichment analyses showed upregulation of neutrophil and innate immune pathways, but downregulation of T-cell and adaptive immune-activation pathways proportional to severity score. This finding was independent of lymphocyte count and despite reduction in immunosuppression in most patients. Comparison with post-acute cases showed "normalization" of these enriched pathways after >4 weeks, suggesting recovery of adaptive immune system activation despite reinstitution of immunosuppression. In summary, blood transcriptome of kidney transplant patients with COVID-19 shows decrease in T-cell and adaptive immune activation pathways during acute disease that associate with severity despite immunosuppression reduction and show recovery after acute illness supporting the approach of temporarily reducing T -cell-directed immunosuppression during acute COVID-19.
This study investigated the occurrence of anti HLA donor specific antibodies (post-Covid DSA) and rejection episodes following Covid-19 with particular focus on immunosuppression modulation. Among 179 patients, the incidence of post-Covid DSA was 4% (8% and 0% in hospitalized and non-hospitalized, respectively). Allograft rejection occurred in 3 patients (1.7%) and all were hospitalized. Younger age, transplantation less than one year and preexisting DSA were more frequently observed in post-Covid DSA positive patients, whereas inflammatory markers, lymphopenia and use of antiviral therapies were not.