Transplantation Updates
Just Released - Transplantation - February 2023 Issue
While there remain a few points we can still learn about in COVID, the main emphasis of research has moved on. In this issue there are some great overviews and commentaries on subjects as wide as: ABOi liver transplantation; the role of machine perfusion in abdominal and cardiac retrieval; desensitization; biomarkers in lung and in cardiac transplantation; outcomes from SPK transplants; and some basic science studies looking at intracellular tacrolimus in lymphocytes and monocytes, as well as some nice work dissecting differences in Intragraft and lymph node B cells.
Table of Contents
Around the World
Research Highlights
Game Changer
Special Article
People in Transplantation
Expert Insight
Commentaries
- Monkeypox a Concern for Donor-derived Infection?
- Intragraft B Cells, Just Not Like the Others
- Commentary on “Lung Transplantation for COVID-19 Pulmonary Sequelae”: Beautiful Story, Already History?
- Replacing the Endomyocardial Biopsy: Easier Said Than Done
- Amelioration of Diabetes and Neuropathy After Pancreas Transplantation: Measurable Differences in Vibration Perception Thresholds Impact Outcomes
- In Situ Normothermic Regional Perfusion in Controlled Donation After Circulatory Determination Death: Organ Utilization, Outcomes, and Elusiveness of a Randomized Clinical Trial”
Reviews
- Current Status of ABO-incompatible Liver Transplantation
- Abdominal Organ Preservation Solutions in the Age of Machine Perfusion
- Biomarkers for Chronic Lung Allograft Dysfunction: Ready for Prime Time?
- Desensitization in Crossmatch-positive Kidney Transplant Candidates
- Heart Transplantation From DCD Donors in Australia: Lessons Learned From the First 74 Cases
Original Basic Science
- TIGIT-Fc Prolongs Corneal Allograft Survival in Mice by Upregulating TIGIT/CD226 Expression and the Proportion of Helios+Foxp3+ Treg Cells
- P-glycoprotein, FK-binding Protein-12, and the Intracellular Tacrolimus Concentration in T-lymphocytes and Monocytes of Kidney Transplant Recipients
- The Novel MyD88 Inhibitor TJ-M2010-5 Protects Against Hepatic Ischemia-reperfusion Injury by Suppressing Pyroptosis in Mice
- Transcriptionally Distinct B Cells Infiltrate Allografts After Kidney Transplantation
Original Clinical Science—Liver
- Impact of Donor Liver Macrovesicular Steatosis on Deceased Donor Yield and Posttransplant Outcome
- Nodular Regenerative Hyperplasia Is Not a Rare Condition After Liver Transplantation: Incidence, Predictive Factors, and Impact on Survival
- Personality Traits in Patients With Cirrhosis Are Different From Those of the General Population and Impact Likelihood of Liver Transplantation
- The Conundrum of Patients With Compensated Cirrhosis Requiring Kidney Transplantation; Kidney Alone or Simultaneous Liver Kidney Transplantation
Original Clinical Science—General
- Improved Organ Utilization and Better Transplant Outcomes With In Situ Normothermic Regional Perfusion in Controlled Donation After Circulatory Death
- Lung Transplantation for COVID-19 Pulmonary Sequelae
- Dynamics of Humoral and Cellular Responses in Renal Transplant Recipients Receiving 3 Doses of SARS-CoV-2 mRNA Vaccine
- Alpha-cardiac Actin Serum Expression Levels Detect Acute Cellular Rejection in Heart Transplant Patients
- Diabetic Neuropathy Is Independently Associated With Worse Graft Outcomes and Incident Cardiovascular Disease After Pancreas Transplantation: A Retrospective Cohort Study in Type 1 Diabetes
- The Molecular Diagnosis Might Be Clinically Useful in Discrepant Kidney Allograft Biopsy Findings: An Analysis of Clinical Outcomes
- Anti-interleukin-6 Antibody Clazakizumab in Antibody-mediated Renal Allograft Rejection: Accumulation of Antibody-neutralized Interleukin-6 Without Signs of Proinflammatory Rebound Phenomena
- Apheresis of Deceased Donors as a New Source of Mobilized Peripheral Blood Hematopoietic Stem Cells for Transplant Tolerance
- Dynamics of Human Anelloviruses in Plasma and Clinical Outcomes Following Kidney Transplantation
- Recipient and Graft Outcomes in Simultaneous Kidney and Pancreas Transplantation With Steroid Avoidance in the United States
- Transplantation of Organs From DCD and DBD Donors Who Died After Ligature Asphyxiation
- Analysis of Native Kidney Function Recovery With Renal Scintigraphy Following Simultaneous Liver-Kidney Transplantation
Letters to the Editor
- Kidney Transplant Patients Generate Varicella Zoster–Reactive T-cell and Humoral Immunity Following Protein-based Varicella Zoster Vaccination
- COVID-19 Outcomes in Solid Organ Transplant Recipients Who Received Tixagevimab-cilgavimab Prophylaxis and/or Bebtelovimab Treatment in a Nurse-driven Monoclonal Antibody Program During the Omicron Surge
- First Booster of SARS-COV-2 mRNA Vaccine Is Not Associated With Alloimmunization and Subclinical Injury of Kidney Allograft
- Detection of Transmissible Severe Acute Respiratory Syndrome Coronavirus-2 From Deceased Kidney Donors: Implications for Kidney Transplant Recipients
- First Experience of Optimization of Tacrolimus Therapeutic Drug Monitoring in a Patient Cotreated With Nirmatrelvir/Ritonavir: How Microsampling Approach Changes Everything
- Complete Endovascular Stenting of the Inferior Vena Cava Following Its Twisting After Liver Transplantation
- Immunogenicity, Reactogenicity, and Reinfection After 2 Doses of the Inactivated Whole-virion CoronaVac Vaccine in Kidney Transplant Recipients Convalescents From COVID-19
Transplantation - Highlighted Tweets
There is no standard definition for “HLA incompatible” transplants. For the first time, we systematically assessed how HLA incompatibility was defined in contemporary peer-reviewed publications and its prognostic implication to transplant outcomes.
The effectiveness of the fourth BNT162b2 vaccination in reducing the rate and severity of coronavirus disease 2019 (COVID-19) caused by the Omicron variant in renal transplant recipients (RTRs) is unknown.
Transplantation Direct - Highlighted Tweets
Successful intestinal transplantation is currently hindered by graft injury that occurs during procurement and storage, which contributes to postoperative sepsis and allograft rejection. Improved graft preservation may expand transplantable graft numbers and enhance posttransplant outcomes. Superior transplant outcomes have recently been demonstrated in clinical trials using machine perfusion to preserve the liver. We hypothesized that machine perfusion preservation of intestinal allografts could be achieved and allow for transplantation in a porcine model.
Studies have shown that coronavirus disease 2019 (COVID-19) vaccination is associated with a lower humoral response in vulnerable kidney patients. Here, we investigated the T-cell response following COVID-19 vaccination in kidney patients compared with controls.
CIRTA 2023 - Abstract Submission Deadline: February 1st, 2023
Submit your abstract to CIRTA 2023 and join us in beautiful Chicago this summer!
ITS 2023
IPITA/HSCI/JDRF Summit - Abstract Submission Deadline!
2023 Organ Donation Congress
Women in Transplantation
Early Career Pillar Member - Expression of Interest
Women in Transplantation is aiming to open a place on Pillars 1 and 3 to transplant professionals who are early in their careers.
2023-2025 WIT Fellowship Grants and
Inaugural LMIC Fellowship Grant for Research in Gender and Sex in Transplantation
TTS 2024
30th International Congress of The Transplantation Society (TTS 2024)
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