Steroid avoidance in kidney transplantation has been proven noninferior. Long-term outcome data on steroid avoidance in simultaneous pancreas-kidney (SPK) remains scant. Utilizing the Scientific Registry of Transplant Recipients between 2000 and 2020, we studied all primary crossmatch negative SPK recipients (N = 5683) who received antithymocyte globulin induction and were discharged alive with functioning grafts on tacrolimus and mycophenolate ± steroid maintenance.
Solid organ transplantation is an established treatment of choice for end-stage organ failure. However, all transplant patients are at risk of developing complications, including allograft rejection and death. Histological analysis of graft biopsy is still the gold standard for evaluation of allograft injury, but it is an invasive procedure and prone to sampling errors.
The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug–drug interactions. Although various strategies have been proposed to improve treatment outcomes in these patients, several uncertainties remain, and consensus practice guidelines are just beginning to emerge. The main objective of this scoping review was to map the extent of the literature on the pharmacotherapeutic interventions performed by healthcare professionals for PLWHIV undergoing SOT.
Early-bird registration ends today
March 13, 2023!
Join us in Niagara-on-the-Lake and contribute to an exciting and stimulating scientific meeting that will inspire and challenge you!
The ITS 2023 will provide a forum for presentations and discussions of cutting-edge basic and translational science in and beyond transplantation. This meeting will not only serve as an international platform for scientific discussions on the latest ground-breaking discoveries in the field, but will also provide an excellent opportunity to present your own work to the scientific community. We hope this will allow for the exchange of new ideas and establishment of collaborative work between senior scientists, young professionals and early-stage researchers.