Just Released - Transplantation Journal - September Issue
This issue includes some fascinating science on advances in kidney organoids, humanized mouse transplant models using CAR-T cells and memory CD8 cells, as well as offering direction on the clinical problems of donor obesity, infectious disease and patient-reported outcomes. The value of NAC in liver transplantation and HCC resection vs. liver transplantation for HCC are explored. The clinical science section includes novel findings on bariatric surgery for kidney donors, robotic nephrectomy and ex vivo perfusion of kidneys for simultaneous heart-kidney transplantation, as well as endomyocardial biopsies and miRNAs for rejection monitoring in heart transplantation. Belatacept treatment in pregnant transplant recipients is evaluated. Further interesting insights are offered in a meeting report on sex and gender in organ transplantation. Two important guidelines are provided, one on Banff scoring of recurrent IgA nephropathy and the other on Infectious disease in South Asia.
Table of Contents
Around the World
Research Highlights
Game Changer
- Biological Time Travel: Tracking the Journey of Alloreactive T Cells Through Longitudinal Biobanking
Meeting Report
Expert Insight
Commentaries
- CAR-T Cells: A New Tool for Monitoring T-cell Alloreactivity?
- N-acetylcysteine and Reduction of Ischemia-reperfusion Injury in Liver Transplantation
- Anything But a Biopsy: The Quest for Noninvasive Alternatives in Heart Transplantation
- The Enigma of Heart-kidney Transplantation
- Organ Donation and Transplantation in China
Reviews
- Kidney Bioengineering for Transplantation
- Novel Endpoints in Solid Organ Transplantation: Targeting Patient-reported Outcome Measures
- Obesity and Kidney Transplantation—How to Evaluate, What to Do, and Outcomes
- South Asian Transplant Infectious Disease Guidelines for Solid Organ Transplant Candidates, Recipients, and Donors
Original Basic Science
- Human A2-CAR T Cells Reject HLA-A2+ Human Islets Transplanted Into Mice Without Inducing Graft-versus-host Disease
- Failure of Costimulatory Blockade-induced Regulatory T Cells to Sustain Long-term Survival of High Ischemic Allografts
- Protective Effect of Calpain Inhibition During Cold Ischemia on Ischemia–reperfusion Injury After Lung Transplantation
- In Vivo Regeneration of Tubular Small Intestine With Motility: A Novel Approach by Orthotopic Transplantation of Decellularized Scaffold
Original Clinical Science—Liver
- Surgical Treatment of Hepatocellular Carcinoma: Multicenter Competing-risk Analysis of Tumor-related Death Following Liver Resection and Transplantation Under an Intention-to-treat Perspective
- N-acetylcysteine in the Donor, Recipient, or Both Donor and Recipient in Liver Transplantation: A Systematic Review With Meta-analysis and Trial Sequential Analysis
- Vibration Controlled Transient Elastography to Evaluate Steatosis in Candidate Living Donors for Liver Transplantation
- Serum CXCL8 Concentration Can Be Used as a Noninvasive Marker of Subclinical Rejection After Pediatric Liver Transplantation
Original Clinical Science—General
- Robotic Versus Laparoscopic Donor Nephrectomy: A Retrospective Bicentric Comparison of Learning Curves and Surgical Outcomes From 2 High-volume European Centers
- Bariatric Surgery in Severely Obese Kidney Donors Before Kidney Transplantation: A Retrospective Study
- Cost-effectiveness of Kidney Transplantation From Donors at Increased Risk of Blood-borne Virus Infection Transmission
- Simultaneous Heart-kidney Transplant With Planned Delayed Implantation of the Kidney Graft After Ex Vivo Perfusion
- Outcomes With Belatacept Exposure During Pregnancy in Kidney Transplant Recipients: A Case Series
- Evaluation of the Modified Oxford Score in Recurrent IgA Nephropathy in North American Kidney Transplant Recipients: The Banff Recurrent Glomerulonephritis Working Group Report
- Combining Serum miR-144-3p and miR-652-3p as Potential Biomarkers for the Early Diagnosis and Stratification of Acute Cellular Rejection in Heart Transplantation Patients
- Fecal Microbiota Transplant in Pediatric Solid Organ Transplant Recipients
Letters to the Editor
- TikTok and Transplantation: A Trending Opportunity
- Graft Hysterectomy After Uterus Transplantation With Robotic-assisted Techniques
- Tixagevimab–cilgavimab Preexposure Prophylaxis in Solid Organ Transplant Recipients Is Associated With Fewer Breakthrough SARS-CoV-2 Infections, Except During the BA.5 Period
Letters to the Editor
ISVCA 2023: “The Next Era of VCA: Decisions and Dilemmas”
Save the Date for ISVCA 2023!
Book Your Room Today!
Sofitel - Beverly Hills
The Sofitel Los Angeles at Beverly Hills is a luxury urban resort hotel & spa featuring a rooftop pool, an outdoor garden patio and a trendy bar with craft cocktails, delicious bar bites and famous daily entertainment from Jazz to Salsa. Ideally located across of the street of L.A. largest shopping mall the Beverly Center, within 2mi. of Rodeo Dr, Sunset Blvd, the Grove & the Academy Museum.
8555 Beverly Blvd., Los Angeles, CA, 90048
Location/Room Reservations:
- Follow the link: www.sofitel-los-angeles.com
- Select Your Dates
- Enter pref code: CSBI23
Guest Rooms: We are recommending all guests drive in for this event. If you do require a guest room details are below. All guest room fees are at individual expense.
Preliminary Program
DAY 1: Friday, December 1, 2023
Novel Technologies in VCA I
Novel Technologies in VCA II
Hand Transplantation in India
Current Approaches to Bilateral Hand Transplantation
Operative Strategies and Functional Analysis
Pediatric Hand Transplantation
State of the Art of Uterus Transplantation
VCA for Gender Affirmation
Penile Transplantation
Eye Transplantation
Immunosupression Complications and Cancer Screening in VCA
Novel Immunosupression Regimens in Solid Organ Transplantation
DAY 2: Saturday, December 2, 2023
The Face: To Reconstruct or Transplant?
Transplantation of The Face: Where Do We Stand?
The Future of the VCA Registry
Trainee Abstract Session 2
VCA Clinical Regional Updates: U.S., Europe, Asia, South America
Multicenter Studies for VCA
We look forward to the 2023 Meeting of the International Society of Vascularized Composite Allotransplantation - “The Next Era of VCA: Decisions and Dilemmas” at Sofitel Beverly Hills, Los Angeles, December 1-2, 2023.
The conference will consist of a packed 2-day agenda with the world’s leaders in reconstructive transplantation (the transplantation of hand, face, genitourinary tissue, uterus or abdominal wall). Sponsored by Cedars-Sinai Medical Center, the newest presence in VCA research and practice, our key focuses for this event are:
- Translational Science Advances
- Clinical Science
- World Regional Updates
- twork Potential - National and International
We look forward to seeing you in beautiful Los Angeles, California.
Curtis L. Cetrulo, Jr.
M.D., FACS, FAAP
ISVCA, President
M.D., FACS, FAAP
ISVCA, President
Transplantation Journal Highlights
Transplantation - Highlighted Tweets
Cytomegalovirus High-risk Kidney Transplant Recipients Show No Difference in Long-term Outcomes Following Preemptive Versus Prophylactic Management
Following kidney transplantation (KT), cytomegalovirus (CMV) infection remains an important challenge. Both prophylactic and preemptive antiviral protocols are used for CMV high-risk kidney recipients (donor seropositive/recipient seronegative; D+/R–). We performed a nationwide comparison of the 2 strategies in de novo D+/R– KT recipients accessing long-term outcomes.
Impact of Spousal Donation on Postoperative Outcomes of Living-donor Lobar Lung Transplantation
The effect of human leukocyte antigen mismatches between donors and recipients on postoperative outcomes of lung transplantation remains controversial. We retrospectively reviewed adult recipients receiving living-donor lobar lung transplantation (LDLLT) to examine the difference in de novo donor-specific antibody (dnDSA) development and clinically diagnosed unilateral chronic lung allograft dysfunction per graft (unilateral CLAD) between lung grafts donated by spouses (nonblood relatives) and nonspouses (relatives within the third degree). We also investigated the difference in prognoses between recipients undergoing LDLLTs including spouse donors (spousal LDLLTs) and not including spouse donors (nonspousal LDLLTs).
Transplantation Direct - Highlighted Tweets
Loss of Endothelial Glycocalyx During Normothermic Machine Perfusion of Porcine Kidneys Irrespective of Pressure and Hematocrit
Normothermic machine perfusion (NMP) is a promising modality for marginal donor kidneys. However, little is known about the effects of NMP on causing endothelial glycocalyx (eGC) injury. This study aims to evaluate the effects of NMP on eGC injury in marginal donor kidneys and whether this is affected by perfusion pressures and hematocrits.
Sociodemographic Variables in Canadian Organ Donation Organizations: A Health Information Survey
Health systems must collect equity-relevant sociodemographic variables to measure and mitigate health inequities. The specific variables collected by organ donation organizations (ODOs) across Canada, variable definitions, and processes of the collection are not defined. We undertook a national health information survey of all ODOs in Canada. These results will inform the development of a standard national dataset of equity-relevant sociodemographic variables.
TTS-ISN Sister Centers Application Submission - Deadline October 15
Reminder 2023 Proposed TTS By-law Changes
Deadline to submit your ballot is October 21, 2023
TTS Council is pleased to present eight proposed By-law amendments to aid in shaping the future of the Society.
Among the changes proposed are expansion of Council to increase diversity, ensuring female, early career and Middle East AND Africa countries representation. TTS encourages all full members to actively participate by voting before the ballot closes September 21. To review the proposed by-law amendments and the rationale statements please click the link below.
If you are a TTS full member you should have received an e-mail with your personalized voting link today. Alternatively you may use the link above to submit your ballot.
Contact
Address
The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada