It is my great honor and pleasure to announce the 1st Regional Meeting of The Transplantation Society to be held in Istanbul on 28-29 March, 2019.
Although organ transplantation has become the treatment of choice for end stage organ disease, it is important to recognize that organ shortage is the greatest challenge facing the field of organ transplantation today. This is unfortunately particularly true for countries in the Middle East, Africa and Mid Asia, where deceased donation rates are very low or, as in some countries, nonexistent. It is nevertheless important to note that there is significant effort in the region to turn this around, such as in Iran where they have succeeded in establishing deceased donation programs that rival those in Europe and the rest of the world.
As outcomes of transplantation have improved, the number of transplant candidates listed for deceased donor transplantation has increased dramatically over the years. In light of these concerns, the theme "Deceased Donation: Expanding the Donor Pool," will provide valuable insights into medical, legislative, ethical, cultural, and social hurdles that must be overcome to increase deceased donation rates in the region as well as the world. The combined regions of the Middle East, Africa and Mid Asia comprise almost 90 countries and is home to a quarter of the world's population, all of whom are affected by organ donation and transplantation activities and policies in their countries. The Scientific and Local Organizing Committees, comprised of international leaders in transplantation, are committed to providing a program that reflects current concerns and perspectives presented in an environment and format that encourages interactions between scientific disciplines and across international borders.
We look forward to welcoming you to Istanbul to take part in the scientific and social events and to experience Turkish hospitality at its best.
Mehmet Haberal, MD
FACS (Hon), FICS (Hon), FASA (Hon), FIMSA
President, The Transplantation Society
Chair, 1st Regional Meeting of The Transplantation Society
The TTS-ILTS Paired Transplant Centers Program is a collaboration between The Transplantation Society (TTS) and the International Liver Transplantation Society (ILTS) supporting new liver transplant programs in emerging countries.
The 6th Solid Organ Transplantation Related Infections Course was organized by TOND-SONE (Turkish Transplantation Society – Solid Organ Transplantation Infections Study Group) in Istanbul, Turkey on 13-14 October 2018. The study group comprised of members of TOND and SONE is a national group composed of infectious disease specialists as well as transplant surgeons, pulmonologists, pathologists, nephrologists, and gastroenterologists.
The course was held with the attendance of 70 infectious diseases specialists from various parts of Turkey. The scientific course focused on current problematic areas in the field of transplantation related infections.
The meeting was opened by Prof. Mehmet Haberal, President of TOND and TTS, and was followed by scientific sessions covering current national legislation, new insights into the field, diagnostic algorithms of bacterial, fungal and viral infections, and difficult-to treat infections. Interactive discussions of case presentations also received great attention from the audience. Emphasis was made on the importance of scientific research involving multicenter studies as well as collaborations with international societies. The multidiscipline nature of transplantation enriched the program with contributions to the program from surgeons, pulmonologists, and pathologists among others.
TOND-SONE has 6 specific study groups: donor and recipient screening, legislation, bacterial infections, viral infections, fungal infections, and tuberculosis. The meeting provided a forum for these study groups to report their activities as well as finalize action plans for the following year.
The sessions were interactively arranged to allow the audience to ask questions and comment on the course materials, resulting in positive feedback from the participants with general consensus that the course should continue to be organized annually.
Dr Andrea Schlegel, Editorial Fellow, Transplantation.
Reduced Access to Liver Transplantation in Women: Role of Height, MELD Exception Scores, and Renal Function Underestimation
Allan AM, Heimbach JK, Larson JJ, et al.
The authors assessed sex-based inequities in liver allocation in the United States. Based on 90 720 adult OPTN registrations between 2002 and 2013, authors explored sex-specific differences in waitlist mortality and liver transplantation. The authors also addressed a potential underestimation of renal function by MELD score and explored if the correction of deficient MELD points could improve potential deficits in access to liver transplantation (LT).
Interestingly, women had not only a significantly higher waiting list mortality but also a 9-20% lower likelihood of receiving a liver transplantation, depending on the region and biologically plausible variances. Differences in recipient height and MELD exception points accounted for the lower accessibility of female patients. Additionally, female transplant candidates received between 1 - 2.4 fewer creatinine-derived MELD points compared to men, with similarly impaired kidney function. Interestingly, the addition of 1 or 2 MELD points in women improved access to LT significantly. The authors conclude, that the level of underestimated disease severity by the MELD score in women impacted liver allocation significantly.
This work explains some sex-based inequalities in liver allocation and may ask for future amendments for MELD exception scores necessary to avoid sex-based inequalities in liver allocation.
October 16 - Dying to Live' reveals that Australia lags behind similar countries in organ and tissue donor rates, causing immense suffering for those awaiting organs, while other Australians inspire us, with their compassionate, life-saving gift, to become physical philanthropists.
This week, the government of Kerala announced its intention to implement mandatory requirement for brain death reporting in intensive care units of the state, de-linking it from organ donation. This was done in response to concerns raised by civil society organisations about the perception of selective brain-death declarations in order to facilitate removal and transplantation of organ to benefit a more affluent section of society who are treated in private hospitals.
October 11 - A Meet-the-Professor session at ID Week 2018 held in San Francisco, California, took a look at the infectious disease risks posed by transplantation and what the future might have in store as the scope of transplantation expands.
October 18 - Child patients will be given priority in kidney transplants when there is a brain-dead or non-heart-beating donor under a new agreement on organ transplantation between three major hospitals in HCM City.
The International Pediatric Transplant Association is proud to feature a special section activity: the 2018 Symposium in Organ Transplantation in Children: An educational forum for physicians, surgeons, and allied health professionals.
The focus of this symposium is aimed at clinical and research fellows in pediatric solid organ transplantation, as well as residents, and other allied health professional or non-physician trainees who are planning a career in pediatric transplantation.