An array of new data and ideas combined with some long term assessments are to be found in this issue. Circulating donor mitochondrial DNA might be a helpful biomarker in DGF, decreased SIRT1 and BOS may herald clues for lung transplantation, while studies of mixed chimaerism range from the application of nanostring technology early post-transplant to a 20-year follow up of the combined BMT/Kidney Transplant approach to patients with Myeloma. The problems of the thin and the fat and how to optimize liver allocation remain hot topics with some new insights.
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The Banff Foundation for Allograft Pathology has constructed a digital pathology survey in preparation for finalizing a digital pathology white paper for transplant pathology. Here are background links for the white paper:
Please complete the survey at your earliest convenience at www.surveymonkey.com/r/6856VDW, but no later than November 10.
Dr. Peri Husen, Editorial Fellow, Transplantation
Schenk AD, Washburn WK, Adams AB, et al.
Transplantation Direct: October 2019 - Volume 5 - Issue 10 - p e494
In this article, Schenk and coworkers address the issue of procurement-related travel safety, as transplantation is a unique specialty in which surgical transplant teams routinely travel by air and ground to remote donor hospitals at night or tough weather conditions. In order to assess the experiences made and attitudes formed, these individuals (surgeons and members of ASTS on the mailing list in August 2017) were addressed via a 32-question survey. Current travel practices, accident frequency and surgeons’s perception of risk were among the parameters assessed. Interestingly, 23% of respondents reported involvement in at least 1 procurement-related travel accident, and 11% of respondents actually felt „very safe“. Since the shift to broader distribution of organs accurs throughout all organ groups, the average distance between site of procurement and recipient hospital will increase. This could lead to an increase in travel-related accidents. One suggestion of the authors to address this issue, is to pursue procurement by local teams closest to the donor site and transporting the organs to the recipient site later, rather than transporting recovery teams from the recipient hospital. Overall, the aspect of provider safety should be a dominant aspect of procurement practices, which the authors in this article neatly address.
The TTS-ILTS Paired Transplant Centers Program is a collaboration between The Transplantation Society (TTS) and the International Liver Transplantation Society (ILTS) supporting new liver transplant programs in emerging countries.VISIT WWW.TTS-ILTS.ORG FOR FULL DETAILS
Oct. 24 - Robert Chelsea turned down the first face he was offered. It was a fine face, one that could have taken him off the transplant waiting list after just a couple months. The face, offered in May 2018, had belonged to a man with skin that was much fairer than what remained of Chelsea’s—so light that Chelsea, who is African American, couldn’t bear the thought of becoming “a totally different looking person.
Oct. 25 - Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace.
Oct. 28 - Although more women than men worldwide have chronic kidney disease, fewer women receive renal replacement therapy (RRT) such as dialysis and kidney transplants, according to a new online report published in the Clinical Journal of the American Society of Nephrology.
Oct. 24 - A recent study identified the pretransplant characteristics contributing to delayed engraftment (DE) following autologous hematopoietic cell transplantation (AHCT). DE after allogenic transplant is well described, but the authors said they conducted this study because the incidence and clinical characteristics associated with prolonged cytopenias in those receiving AHCT is not well known. The authors said it was the first study to report on these pretransplant factors that contribute to DE.
Oct. 29 - It is hoped the vaccine will provide long-term protection against the disease, which kills 1.5 million people around the world each year.
ITS 2019 is set for Nov. 10-13 in Clearwater Beach, Florida. Keynote speakers include Katherine High, President and Head of R&D at Spark Therapeutics, and Ronald Germain, chief of Laboratory of Immune System Biology and Lymphocyte Biology Section at the National Institute of Allergy and Infectious Diseases National Institutes of Health.
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