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Upcoming and Recorded Webinars

ISN-TTS JOINT WEBINAR
Donor/Recipient Pair: Infections

TUESDAY, APRIL 6, 2021
3:00 PM CEST / 9:00 AM EST (MONTREAL TIME)

Open to all healthcare professionals

Speaker: Camille Nelson Kotton, Boston, USA
Moderator: Stephanie Pouch, Atlanta, USA

Free to attend

Wednesday, April 7, 2021
2:00PM - 6:00PM (İstanbul Time Zone)

The Middle East Society For Organ Transplantation (MESOT) invites you to a new webinar on How to Increase Organ Donation and Transplantation in Our Region during the Covid-19 Pandemic Period.

With COVID-19 pandemic spreading across the globe since last year, it had the immediate effect of severely reducing living and deceased organ donation and transplantation activity worldwide.

IPTA AHNP - PHTS WEBINAR

April 13, 2021
4:00 PM CET / 11:00 AM EDT (MONTREAL TIME)

Open to all healthcare professionals

IPTA AHNP - PHTS WEBINAR - TUESDAY, APRIL 13, 2021 - 11:00AM EST (MONTREAL TIME)

ISN-TTS JOINT WEBINAR
Donor/Recipient Pair - Risks vs Gains - Kidney Function

March 23, 2021

Speaker: Marcelo Cantarovich, Montreal, QC, Canada
Moderator: Jean Tchervenkov, Montreal, QC, Canada

RECORDING NOW AVAILABLE

Journal Updates

WEEK'S MOST
DOWNLOADED PAPER

Ethical Issues in the COVID Era: Doing the Right Thing Depends on Location, Resources, and Disease Burden
Stock, Peter G.; Wall; Gardner, James; Domínguez-Gil, Beatriz; Chadban, Steve; Muller, Elmi; Dittmer, Ian; Tullius, Stefan G.; TTS Ethics Committee
The transplant community is well-versed in ethical issues surrounding the allocation of scarce resources, but the COVID-19 pandemic has escalated moral dilemmas of transplantation far beyond simply allocation of limited donor organs. Emanuel et al1 were unfortunately prophetic in their recent NEJM article addressing the ethical principles guiding medical decisions during the COVID-19 pandemic and the associated depletion of resources. Hospital and intensive care resources are becoming severely limited in high-transmission areas, influencing decisions about who should be transplanted and affecting the availability of donated organs.

Highlighted Visual Abstracts

 
 

Survey - What infection outcomes in kidney transplantation are important to you?

TTS is an Official SONG Project collaborator - www.songinitiative.org
“Infection” is a core outcome domain that patients, caregivers and health professionals agree is critically important to report in all research (clinical trials) in kidney transplantation. We invite you to participate in a 5-10 minute survey that aims to find out which infection outcomes are most important to patients, caregivers and health professionals. This will help to ensure that the most relevant infection outcome will be reported in research to inform decision-making. The survey is voluntary and will close 31 March 2021 and all participants will receive a copy of the results.

Section Spring Newsletters

IPTA March Newsletter

In this issue

Presidential Message | IPTA 2022 | Literary Review – Education Committee | Publications Committee | Allied Health & Nursing Committee Update | IDCARE Committee | Outreach Committee | Pediatric Transplantation Journal | Meet the Greats!  | IPTA Virtual Journal Club | PTLD book

IXA March Newsletter

In this issue

In Memoriam |  Our Congress dates have changed!  | Council Nominations  | 2020 Xeno-Prize  | Young Investigators Award in Xenotransplantation | GalSafeTM pigs | 2020 ESOT Transplant Learning Journey 2.0 Young INvestigator Committee | Council Communication Initiative

Highlighted News - NKF (USA) Releases Commentary on Transplant Practices

March 18, 2021 — Today, the National Kidney Foundation (NKF) unveiled a review by its Kidney Disease Outcomes Quality Initiative (KDOQI) of the global Kidney Disease Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation. Published online in the American Journal of Kidney Diseases, it includes a general endorsement as well as additional guidelines.

Highlighted Video

'It's Kind of a Catch-22': Immunosuppression and COVID-19 Vaccines

MedPage Today Op-Ed by Dorry Segev, MD, PhD - March 15, 2021
Marty Makary, MD (Editor-in-Chief, MedPage Today) speaks with Dorry Segev, MD, PhD, on implications of his real-world study

Hot off the Press 

«HOT OFF THE PRESS» 
RECENT PUBLICATIONS IDENTIFIED
BY TTS EDUCATION COMMITTEE ON COVID-19

Selected Publications by TTS Education Committee. This week's selection made by Drs. Enver Akalin and Millie Samaniego..

Mortality among solid organ waitlist candidates during COVID‐19 in the United States

Jonathan Miller et al. Am J Transplant. 2021; DOI: 10.1111/ajt.16550
This study used 3 separate piecewise exponential survival models estimated for each solid organ the overall, demographic‐specific, and donation service area‐specific differences in the hazard of waitlist mortality before and after the national emergency declaration on March 13, 2020. Kidney waiting list mortality was higher after than before the national emergency (adjusted hazard ratio [aHR], 1.37; 95% CI, 1.23–1.52). The hazard of waitlist mortality was not significantly different before and after COVID‐19 for liver (aHR, 0.94), pancreas (aHR, 1.01), lung (aHR, 1.00), and heart (aHR, 0.94). Kidney candidates had notable variability in differences across donation service areas (aHRs, New York City, 2.52; New Jersey, 1.84; and Michigan, 1.56). The only demographic group with increased waiting list mortality were Blacks versus Whites (aHR, 1.41; 95% CI, 1.07–1.86) for kidney candidates.

Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination Venkata Viswanadh Edara et al.

Venkata Viswanadh Edara et al. JAMA Published online March 19, 2021. doi:10.1001/jama.2021.4388
20 acutely infected, 20 convalescent and 14 mRNA vaccinated patients were studied for neutralizing activities to 4 SARS-CoV-2 mutations. This study found neutralizing activity of infection- and vaccine-elicited antibodies against four SARS-CoV-2variants, including B.1, B.1.1.7, and N501Y. Because neutralization studies measure the ability of antibodies to block virus infection, these results suggest that infection- and vaccine induced immunity may be retained against the B.1.1.7 variant.

Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

Christien Holm Hansen et al. Lancet published online March 17, 2021. https://doi.org/10.1016/ S0140-6736(21)00575-4
This study analyzed people who tested positive for the coronavirus during one or both of Denmark’s two surges of infection — from March to May and from September to December — in 2020. At about 6 months after initial infection, protection against repeat infection was approximately 80%, with no significant difference in reinfection rates between men and women. But this protection was reduced to 47% for those aged 65 years or older, emphasizing the need to prioritize vaccinations for this group.

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