Official Sections CTRMS ISVCA IPITA IPTA ISODP IRTA IXA SPLIT TID

2018 - Online Interactive Update Course (en, sp, pt)


This page contains exclusive content for the member of the following sections: TTS, CTS, IPITA, ISODP, IXA, ITA, TID, IHCTAS, IPTA, SPLIT

Treatment of a Rejection

6.1 - Emerging Therapies for Prevention and Treatment of Antibody Injury to Allografts

Presenter: Stanley, Jordan, , United States
Authors: Stanley Jordan

[en] Treatment of a rejection has its ‘ups and downs’ and although evidence has been found, the experts’ opinion still prevails on the current treatments. The classic and intricate cellular and anti-body mediated processes have different approaches, in part.

The dilemma for clinicians is to what extent treat recurring or resistant rejections, either partially or totally. Chronic rejection leads to difficulties and disagreements in its treatment.

How to continue and what maintenance therapy follow in a patient with a rejection - whether it has diminished or not with treatment- is also controversial. These aspects are addressed in the conferences and with the Forum in the present module.


[sp] El tratamiento del rechazo tiene zonas de avance y estancamiento, se han encontrado evidencias pero aún la opinión de expertos sigue rigiendo en mucho los tratamientos actuales. Los clásicos e intrincados procesos celulares y mediados por anticuerpos tienen abordajes diferentes en parte.

Un dilema para los clínicos es hasta dónde y cuánto tratar los rechazos recurrentes o resistentes parcial o totalmente. El rechazo crónico ofrece dificultades y desacuerdos en su tratamiento.

Cómo seguir y qué terapia de mantenimiento instalar en un paciente con rechazo, haya remitido o no con el tratamiento es también un punto de controversia.

Estos aspectos se abordan en las conferencias y foro de este módulo.


[pt] O tratamento da rejeição apresenta zonas de avanço e de dúvidas; existem diretrizes baseadas em evidências, mas a opinião de especialistas ainda prevalece em muitas decisões no tratamento atual. Os clássicos e intrincados processos mediados por células e por anticorpos demandam diferentes abordagens.

Um desafio para os clínicos é até onde levar o tratamento de episódios recorrentes ou resistentes de rejeição. Além disso, a rejeição crônica oferece controvérsias e incertezas em seu manejo.

Por fim, que terapia de manutenção seguir em um paciente com rejeição aguda tratada é também um ponto de debate.

Esses aspectos são abordados nas conferências e no fórum do presente módulo.

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