2011 - 10th Meeting - IHCTAS

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Plenary Session II. Part 1: Immunosuppression

3.2 - The Role of Donor Bone Marrow Chimerism in Promoting Acceptance of VCA

Presenter: Suzanne T., Ildstad, Louisville, KY, USA
Authors: Suzanne T. Ildstad

The Role of Donor Bone Marrow Chimerism in Promoting Acceptance of VCA

Suzanne T. Ildstad, Institute for Cellular Therapeutics, University of Louisville, Louisville, KY, USA.

Learning objectives:

1. Understanding of chimerism and tolerance

2. Status of current studies in chimerism in VCA

Vascularized Composite Allotransplants (VCA) are immunologically complex units, often comprised of a bone marrow component and microenvironment. Chimerism induces donor-specific tolerance. This presentation will highlight the role of donor bone marrow chimerism in promoting acceptance of VCA. It will provide a review of the current status of chimerism from bench to the bedside.

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