Transplantation Updates

Just Released - Transplantation Direct - February 2023 Issue

The February issue of Transplantation Direct is now online. You might be interested to find review articles on the fundamentals of corneal transplantation and on pharmacotherapeutic management of HIV+ organ transplant recipients. We have original articles on the association of coronary artery calcium scores with cardiac events in liver transplant recipients, and with living liver donation - assessment of donor BMI effects on donor and recipient outcomes is examined. In kidney transplantation, a meta-analysis is performed on DGF in relation to short and long -term outcomes and the influence of aortoiliac atherosclerosis on intrarenal vascular resistance is assessed; related to the latter, the influence of cardiologists on rejecting patients for transplant eligibility is appraised. The effects of various combinations of standard immunosuppressants with belatcept on kidney rejection rates is tested, and another study reports on the influence of anti-LG3 and angiotensin II receptor autoantibodies on acute rejection and vascular injury. Also with kidney transplantation, there is an assessment of the US Affordable Care Act on waitlisting and outcomes, and an evaluation of various techniques used to determine urinary microbial inhabitants. In sensitized ESRD patients, the effects of Obinutuzumab (anti-CD20 antibody) on compartmental B cell populations is studied in detail. Full access to all these articles is available on our Transplantation Direct website – we hope you will find time to visit the site soon!

Table of Contents

Review

Overview of Corneal Transplantation for the Nonophthalmologist

Kidney Transplantation

Liver Transplantation

Infectious Disease

Pharmacotherapeutic Interventions in People Living With HIV Undergoing Solid Organ Transplantation: A Scoping Review

Erratum

Kidney Transplantation Confers Survival Benefit for Candidates With Pulmonary Hypertension: Erratum

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Transplantation - Highlighted Tweets

Early in the coronavirus disease 2019 (COVID-19) pandemic, limited testing availability and knowledge about disease transmission raised concern about the safety of using organ donors with positive severe acute respiratory distress coronavirus (SARS-CoV-2) testing. Recent registry reports suggest the safety of this approach, but granular data on such transplants remain limited. We report our single-center experience of 36 nonlung solid organ transplant (SOT) allografts from polymerase chain reaction (PCR) SARS-CoV-2+ donors.

Transplantation Direct - Highlighted Tweet

Islet transplantation is a promising treatment for type 1 diabetes. It has the potential to improve glycemic control, particularly in patients suffering from hypoglycemic unawareness and glycemic instability. As most islet grafts do not function permanently, efforts are needed to create an accessible and replaceable site, for islet grafts or for insulin-producing cells obtained from replenishable sources. To this end, we designed and tested an artificial, polymeric subcutaneous transplantation site that allows repeated transplantation of islets.

ITS 2023

Join us in Niagara-on-the-Lake from April 30 to May 3, 2023 for the 3rd International Transplantation Science Meeting!

CLICK HERE TO REGISTER

Highlights Include:

3 Keynote Speakers
8 Scientific Sessions
Pre-Workshop on "Emerging 'Omics' and Machine Learning Techniques: The Next Frontier in Transplant Research"
Numerous opportunities to network

2023 Organ Donation Congress - Abstracts and Awards

Abstract Submission Deadline: April 12, 2023
Award Application Deadline: May 5, 2023

Enter your submissions today!

Women in Transplantation

Asian WIT Joint Webinar - February 23, 2023

CLICK HERE VIEW THE PROGRAM

CLICK HERE TO SIGNUP

2023-2025 WIT Fellowship Grants and
Inaugural LMIC Fellowship Grant for Research in Gender and Sex in Transplantation

Request for Applications Now Open!
Submission Deadline: April 1, 2023

The Women in Transplantation executive is very excited to announce the 2023 WIT funding opportunities. This year, we are thrilled to be able to support THREE 2-year Fellowships. This will be the third year that we are offering these fellowships.

In addition, for the first time, we are also offering ONE grant open to faculty working in low or middle income countries. This very special new grant will allow transplant professionals working in low and middle income countries to work with an experienced mentor from among the WIT membership to address an important question within their own unique context. We hope that this award will spur exciting international collaborations and build more research capacity in lower resource settings.

Research Fellowship Grant

Click here for more details

Research Fellowship Grant for LMIC

Click here for more details

If you have any further questions and for information on how to apply, please contact Katie Tait (WIT Manager) at katie.tait@tts.org to request more information.

We welcome all applications and look forward to an exciting competition!

Upcoming Presentations

CLICK HERE FOR DETAILS AND TO REGISTER

Latest Recordings

View the recordings (CTRMS / TTS Members Only)

Highlighted Meeting - 2023 World Congress of Nephrology

The World Congress of Nephrology (WCN) is the annual scientific, educational, and networking meeting of the International Society of Nephrology. The WCN features regionally-relevant symposia, presentations, training programs, and courses, offering the latest science and state-of-the-art education in nephrology.

Registration Deadline: March 1

CLICK HERE FOR DETAILS AND TO REGISTER

Highlighted Meeting - 2023 World Congress of Nephrology

The British Transplantation Society’s and NHSBT joint annual Congress will be held at the EICC, Edinburgh from March 1-3, 2023. The British Transplantation Society is an affiliated society of TTS and many TTS and Section members will be presenting at this meeting. Please visit their congress website for full program details as well as registration information.

CLICK HERE FOR DETAILS AND TO REGISTER

In the News

Malaysian National Kidney Foundation starts transplantation subsidy to help needy Malaysian patients

Feb 1. - The National Kidney Foundation (NKF) of Malaysia has introduced a kidney transplant subsidy to help underprivileged patients with a monthly household income of below RM1,800. The subsidy will cover various costs from pre- to post-kidney transplantation including income loss replacement for the work-up and recuperating period for patients seeking transplantation procedures at a government hospital.

2022 organ transplants again set annual records

Jan. 10 - 42,887 organ transplants were performed in the United States, an increase of 3.7 percent over 2021 and a new annual record, according to preliminary data from United Network for Organ Sharing (UNOS), which serves as the national Organ Procurement and Transplantation Network under federal contract. Also for the first year ever, more than 25,000 kidney transplants were performed in the United States. The total of 25,498 marked an increase of 3.4 percent over 2021. In addition, annual records were set for liver (9,528), heart (4,111) and lung (2,692) transplants.

Canada performing more organ transplants from MAID donors than any country in the world

Jan. 18 - A growing number of patients who request medical assistance in dying are asking to donate their organs for transplant, says an international review that found that Canada is performing the most organ transplants from MAID patients among the four countries studied that offer this practice. (Disclaimer - this information is presented as relevant news to our community by our news team)

A Rare Public Health Challenge

Jan. 24 - [NIH Director’s Blog] - More than 10,000 rare diseases affect nearly 400 million people worldwide. In the United States, the prevalence of rare diseases (over 30 million people) rivals or exceeds that of common diseases such as diabetes (37.3 million people), Alzheimer’s disease (6.5 million people), and heart failure (6.2 million people).

New 3D Atlas of Colorectal Cancer Promises Improved Diagnosis, Treatment

Jan. 31 - [NIH Director’s Blog]- Researchers have been busy building the needed tools and also mapping out molecular atlases of common cancers. These atlases, really a series of 3D spatial maps detailing various biological features within the tumor, keep getting better all the time. That includes the comprehensive atlas of colorectal cancer just published in the journal Cell [1].

Disparities in kidney transplant access can be reduced through a multilevel quality improvement effort

Jan. 29 - Study shows kidney transplant inequity among African Americans can be addressed by standardizing the evaluation process and expanding the use of telehealth, among other approaches.

Risk of Subsequent Gastrointestinal Tract Malignancies After Blood or Marrow Transplantation

Jan. 27 - In a study reported in JAMA Oncology, McDonald et al found that receipt of blood or marrow transplantation (BMT) was associated with an increased risk of subsequent malignant neoplasms of the gastrointestinal (GI) tract.

Multi-Drug Resistant Colonization or Infection Linked to Worse Prognosis for Critically Ill Cirrhosis Patients

Jan. 27 - MDR colonization was associated with MDR infection and colonization and infection was linked to higher numbers and duration of antibiotic use.

Kidney Transplant Recipients Do Not Benefit From Infliximab Induction

Jan. 25 - At day 7 after transplantation, production of tumor necrosis factor alpha linked to allograft inflammation had fallen a significant 10-fold in the infliximab vs placebo group.

New research evaluates safety of transplants from organ donors with recent positive SARS-CoV-2 tests

Jan. 25 - The demand for donated organs has already exceeded supply, with patients waiting months and sometimes years for a donor. With so many people testing positive for SARS-CoV-2, the virus that causes COVID-19, a new study published in Transplant Infectious Disease could provide reassurance when it comes to using organs from SARS-CoV-2-positive donors.

Clostridium Difficile Infection Associated With Higher Mortality Rates in Intestinal Transplant Recipients

Jan. 25 - A study published in Transplant Infectious Disease found that Clostridium difficile infection (CDI) is associated with longer hospital stays and higher mortality rates for patients who underwent an intestinal transplant.

KRd Improves PFS as Maintenance Therapy in Transplant-Eligible Multiple Myeloma

Jan. 25 - Maintenance therapy with carfilzomib, lenalidomide, and dexamethasone led to a significant improvement in progression-free survival vs lenalidomide alone in patients with newly diagnosed multiple myeloma who underwent autologous stem cell transplant after induction therapy, according to an unplanned interim analysis of the phase 3 ATLAS trial.

Upcoming Meetings and Announcements

TTS 2024

September 22-25, 2024
Istanbul, Turkey

30th International Congress of The Transplantation Society (TTS 2024)

Member Login

Transplantation Updates

Just Released - Transplantation Direct - February 2023 Issue

Review

Kidney Transplantation

Liver Transplantation

Infectious Disease

Erratum

Transplantation - Highlighted Tweets

Transplantation Direct - Highlighted Tweet

ITS 2023

Join us in Niagara-on-the-Lake from April 30 to May 3, 2023 for the 3rd International Transplantation Science Meeting!

2023 Organ Donation Congress - Abstracts and Awards

Women in Transplantation

Asian WIT Joint Webinar - February 23, 2023

2023-2025 WIT Fellowship Grants and Inaugural LMIC Fellowship Grant for Research in Gender and Sex in Transplantation

Request for Applications Now Open! Submission Deadline: April 1, 2023

Research Fellowship Grant

Research Fellowship Grant for LMIC

Upcoming Presentations

Latest Recordings

Highlighted Meeting - 2023 World Congress of Nephrology

Highlighted Meeting - 2023 World Congress of Nephrology

In the News

Malaysian National Kidney Foundation starts transplantation subsidy to help needy Malaysian patients

2022 organ transplants again set annual records

Canada performing more organ transplants from MAID donors than any country in the world

A Rare Public Health Challenge

New 3D Atlas of Colorectal Cancer Promises Improved Diagnosis, Treatment

Disparities in kidney transplant access can be reduced through a multilevel quality improvement effort

Risk of Subsequent Gastrointestinal Tract Malignancies After Blood or Marrow Transplantation

Multi-Drug Resistant Colonization or Infection Linked to Worse Prognosis for Critically Ill Cirrhosis Patients

Kidney Transplant Recipients Do Not Benefit From Infliximab Induction

New research evaluates safety of transplants from organ donors with recent positive SARS-CoV-2 tests

Clostridium Difficile Infection Associated With Higher Mortality Rates in Intestinal Transplant Recipients

KRd Improves PFS as Maintenance Therapy in Transplant-Eligible Multiple Myeloma

Upcoming Meetings and Announcements

BTS 2023

IPTA 2023

IPITA/HSCI/JDRF Beta Cells Summit

ITS 2023

MESOT 2023

CIRTA 2023

CAST 2023

SPLIT 2023

ISODP 2023

IPITA-IXA-CTRMS Joint Congress

TTS 2024

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2023-2025 WIT Fellowship Grants and
Inaugural LMIC Fellowship Grant for Research in Gender and Sex in Transplantation

Request for Applications Now Open!
Submission Deadline: April 1, 2023