We evaluated whether the use of normothermic regional perfusion (NRP) was associated with increased organ recovery and improved transplant outcomes from controlled donation after circulatory death (cDCD). This is a retrospective analysis of UK adult cDCD donors‚ where at least 1 abdominal organ was accepted for transplantation between January 1, 2011, and December 31, 2019.
Given the central role of sarcomeric dysfunction in cardiomyocyte biology and sarcomere alterations described in endomyocardial biopsies of transplant patients with rejection, we hypothesized that the serum expression levels of genes encoding sarcomeric proteins were altered in acute cellular rejection (ACR). The aim of this study is to identify altered sarcomere-related molecules in serum and to evaluate their diagnostic accuracy for detecting rejection episodes.
Compared with calcineurin inhibitor–based immunosuppression, belatacept (BELA)-based treatment has been associated with better renal function but higher acute rejection rates. This phase 2 study (NCT02137239) compared the antirejection efficacy of BELA plus everolimus (EVL) with tacrolimus (TAC) plus mycophenolate mofetil (MMF), each following lymphocyte-depleting induction and rapid corticosteroid withdrawal.
Join us in Niagara-on-the-Lake from April 30 to May 3, 2023 for the 3rd International Transplantation Science Meeting!
Early-bird registration deadline: March 10, 2023
On Tuesday May 2nd at 17:00-18:00 local time (Eastern Time), all are invited to a special networking event where Dr. Jayne Danska (The Hospital for Sick Children, Toronto, Canada) and Professor Lorna Marson (University of Edinburgh, United Kingdom) will talk about overcoming barriers to career advancement as a woman in the field of transplantation. A discussion will follow. There is no separate registration fee for this event for all who are registered for the ITS meeting, and all are welcome.
On the following morning, Dr. Danska will represent WIT during a session on Influence of Sex and Gender in Transplantation with a talk on "Interactions between Sex and Microbiome Responses", on Wednesday May 3rd at 08:00-09:20 local time.
Leading experts and opinion leaders from all over the world will present the latest data, address critical issues and showcase cutting-edge techniques in clinical and experimental transplant therapy.
Abstract Submission Deadline: April 13, 2023
Award Application Deadline: May 5, 2023
The 18th Congress of the MESOT will be an ideal opportunity to share and learn from peers and in the field. State-of-the-art lectures, plenaries, oral presentations and poster receptions will stimulate deep discussions on the latest scientific research in all fields of organ transplantation in the Middle East, Mid Asia and the world.
MESOT 2023 will be held on May 24-26, 2023 in Ankara, Turkey, and is endorsed by The Transplantation Society (TTS), The Turkish Transplantation Society (TOND) and The Turkic World Transplantation Society (TDTD).
The Transplantation Society
740 Notre-Dame Ouest
Montréal, QC, H3C 3X6