Transplantation Updates

Just Released - Transplantation Direct - May 2023 Issue

The May issue of Transplantation Direct features a very special series of articles resulting from an international organ and tissue donation and transplantation legislation and policies forum. In October 2021, Transplant Quebec and the Canadian Donation and Transplant Research Program organized this forum where 61 participants from 13 countries were invited to produce consensus recommendations aimed to assist nations and geographical regions to establish their own system of organ donation and transplantation, or to improve existing systems. Topics focused primarily on the following areas: baseline ethical principles, legal foundations, consent models and emerging legal issues, donation system architecture, living donation, tissue donation, and research and innovation systems and emerging issues. Consensus and recommendation reports from these topics are the subject of the 7 papers presented in this issue of Transplantation Direct, which will serve as a vital resource for the international organ and tissue donation community. Our editorial group is pleased to publish this important work, and to provide all articles in open access to everyone interested – see our Transplantation Direct website for full details. The videos from the Forum are also available for viewing, see further below for details.

Please also take a look at this May issue with regard to a variety of articles in other subject areas including specific topics in kidney, liver, pancreas and heart transplantation.

Table of Contents


Meeting Report


Organ Donation and Procurement

Liver Transplantation

The videos are available on the forum website. Simply click the link below and create an account for free access.
The videos are also available to TTS Members via our educational library. Click the link below to access.

Transplantation - Highlighted Tweets

In view of the public consultation recently launched by the World Health Organization on Regulatory Convergence of Cell and Gene Therapy Products and the Proposal for a Regulation on substances of human origin (SoHO) repealing the European Union Directives on Blood and on Tissues and Cells, an opportunity arises to define an ethical and transparent framework of collaboration between industry and authorities responsible for SoHO-derived products, comprising medicines, medical devices, transfusion, and transplantation.

Safely increasing organ utilization is a global priority. Donor serum transaminase levels are often used to decline livers, despite minimal evidence to support such decisions. This study aimed to investigate the impact of donor “liver blood tests” on transplant outcomes.

Transplantation Direct - Highlighted Tweet

Both angiotensin II receptor autoantibodies (ATRabs) and autoantibodies to LG3 have been linked to kidney graft rejection with alloimmune vascular injury (AVI). We aimed to examine whether positivity for both anti-LG3 and ATRabs is associated with rejection with AVI in kidney transplant recipients.

Venous thromboembolism (VTE) occurs in 0.4% to 15.5% and bleeding occurs in 20% to 35% of patients after liver transplantation (LT). Balancing the risk of bleeding from therapeutic anticoagulation and risk of thrombosis in the postoperative period is challenging. Little evidence exists regarding the best treatment strategy for these patients.

Declaration of Istanbul Custodian Group at MESOT 2023

Join members of the Declaration of Istanbul Custodian Group and regional experts during this special session, highlighting the position of the DOI in relation to regional legislation and regulation, and specific challenges of the Middle East.

Latest Recordings

The IPTA 2023 Congress recordings are now available for IPTA or TTS Members and Congress attendees!



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