Transplantation - Updates

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Regulatory T Cell Biomarkers Identify Patients at Risk of Developing Acute Cellular Rejection in the First Year Following Heart Transplantation

Acute cellular rejection (ACR), an alloimmune response involving CD4+ and CD8+ T cells, occurs in up to 20% of patients within the first year following heart transplantation. The balance between a conventional versus regulatory CD4+ T cell alloimmune response is believed to contribute to developing ACR. Therefore, tracking these cells may elucidate whether changes in these cell populations could signal ACR risk.

Maximize Donor Cornea Use in a Hepatitis B Endemic Area via Serology Matching

This study aims to investigate the rationality of the allocation guidelines in a hepatitis B endemic area that uses corneas from hepatitis B donors.

Transplantation Direct - Highlighted Tweets

Low C-reactive Protein and Urea Distinguish Primary Nonfunction From Early Allograft Dysfunction Within 48 Hours of Liver Transplantation

Primary nonfunction (PNF) is a life-threatening complication of liver transplantation (LT), but in the early postoperative period, it can be difficult to differentiate from early allograft dysfunction (EAD). The aim of this study was to determine if serum biomarkers can distinguish PNF from EAD in the initial 48 h following LT.

Pre-exposure Prophylaxis with Tixagevimab-cilgavimab did not Reduce Severity of COVID-19 in Lung Transplant Recipients with Breakthrough Infection

Lung transplant recipients (LTRs) have an increased risk of COVID-19–related morbidity and mortality. Tixagevimab-cilgavimab (tix-cil) is a long-acting monoclonal antibody combination granted Emergency Use Authorization approval by the US Food and Drug Administration for COVID-19 pre-exposure prophylaxis (PrEP) in immunocompromised patients. We sought to determine whether tix-cil 300–300 mg reduced the incidence and disease severity of severe acute respiratory syndrome coronavirus 2 infection in LTRs during the Omicron wave.

ISUTx 2023 - Registration is Now Open!

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Join us for two days of engaging panel discussions, presentations, and networking with internationally-renowned faculty and researchers.

The International Society of Uterus Transplantation (ISUTx) is dedicated to scientific innovation and advances in medical care in the field of uterus transplantation.

This year, the ISUTx will commemorate and celebrate the future of the field with this year’s theme — “Uterus Transplantation: The Next Generation.”

We look forward to seeing attendees at the 4th International Congress, which will be held in-person in Birmingham, Alabama at “The Forum” at the Sheraton Birmingham Hotel, on Monday, September 11 – Tuesday, September 12, 2023.

SPLIT 2023 - Early-bird Registration Deadline

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We appreciate your ongoing attendance at our Society’s meeting, which provides excellent educational content and opportunities for fellowship, community and networking. This year’s meeting will mark a number of changes including that our meeting has moved to take place on Monday and Tuesday instead of our usual Thursday/Friday. Additionally, as an official Section of The Transplantation Society we have engaged them as a partner in organizing and supporting the continued growth of our meeting.

We plan on welcoming leading experts and opinion leaders from all over the world to present their latest data and address important needs in clinical pediatric liver transplant and hosting sessions devoted to emerging research in the field.

IPITA-IXA-CTRMS Joint Congress

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Early-bird Registration Deadline: July 24
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The International Pancreas and Islet Transplant Association (IPITA), the International Xenotransplantation Association (IXA), and the Cell Transplant and Regenerative Medicine Society (CTRMS) reaffirm their strong partnership as leaders in transplantation and promise to provide an outstanding and innovative program.

Leading experts and opinion leaders from all over the world will present the latest data and address important needs in clinical and experimental transplant therapy. Specific sessions will be devoted to hot research in whole-organ pancreas transplantation, islet transplantation, stem cell therapy, xenotransplantation and transplant biology.

We are expecting close to 600 delegates from all over the world.

We look forward to welcoming YOU to San Diego!

In the News

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study

July 7 - A new study which developed a new, kidney transplant specific, kidney function equation from a very large cohort of kidney recipients with mGFR (15,000+ patients from 17 cohorts from 8 countries, 50,000+ measured GFR), making this study, among all other GFR equation studies, the study with the highest number of patients.

Illegal organ trade is more sophisticated than one might think - who’s behind it and how it could be controlled

June 27 -Claims are made about the organ trade in the absence of factual data. These have strengthened popular notions of the issue as an underground crime, organised by mafia-like criminals and “rogue” doctors who perform transplants clandestinely. The reality is starkly different. The nature of the organ trade is far removed from these mythical depictions.

Clinical trial set to change kidney transplant practice

July 7 - A major clinical trial has found a simple change to world practice for kidney transplants could deliver real benefits for recipients and reduce their need for dialysis by 25 per cent. The BEST-Fluids trial was conducted by the Australasian Kidney Trials Network (AKTN) in collaboration with researchers from The University of Queensland, The University of Adelaide, and The University of Sydney.

A first for UCLouvain in the fight against organ transplant rejection

July 6 - Profs Laure Bindels and Laure Elens of the University of Louvain (UCLouvain) Louvain Drug Research Institute, supported by Alexandra Degraeve, a UCLouvain FNRS candidate, have been looking into the links between tacrolimus, its dosages, and intestinal microbiota. Their aim has been to determine the factors that influence how the body absorbs and eliminates the drug during transplants.

USA - 11-month-old’s partial heart transplant makes history in Texas. How doctors did it

July 13 - On June 23, doctors, surgeons and researchers from UT Health Austin and Dell Children’s Medical Center successfully completed Elias’ partial heart transplant, according to a July 10 release. “This is a milestone procedure, a partial transplant allows surgeons to tap into a supply of donor hearts that go unused due to deficiencies. We are thrilled with Elias’ progress and we are hopeful this will eliminate the need for future surgeries,” medical director of the pediatric heart failure and transplant program at Dell Med, Chesney Castleberry, said in the release.

Girl receives heart of 4-year-old-boy in first transplant of its kind in Ukraine

July 10 - Amid the raging war and constant threat of Russian missiles, a successful heart transplant has been performed on a 6-year-old girl in Kyiv, authorities with the Heart Institute of Ukraine’s Ministry of Health announced on Monday. It was the first time a heart transplant had been performed in Ukraine on children so young, the institute said.

Kidney transplantation surgeries to be carried out in Kyrgyzstan

July 13 - Kidney transplantation surgeries will be carried out in Kyrgyzstan, head of the information policy service of the Presidential Administration Daiyrbek Orunbekov reported.

First robotic liver transplant in U.S. performed by Washington University surgeons

July 13 - A surgical team from Washington University School of Medicine in St. Louis recently performed the first robotic liver transplant in the U.S. The successful transplant, accomplished in May at Barnes-Jewish Hospital, extends to liver transplants the advantages of minimally invasive robotic surgery: a smaller incision resulting in less pain and faster recoveries, plus the precision needed to perform one of the most challenging abdominal procedures.

USA - A UW Medicine team saved a patient with a dual-organ transplant based on a concept about immunoprotection.

July 13 - Doctors in Seattle are reporting a history-making case in which a patient received two donor organs, a liver and a heart, to prevent the extremely high likelihood that her body would reject a donor heart transplanted alone. In doing so, they successfully tested the concept that a donor liver can confer robust immunoprotection on a subsequent heart transplant.

An important message from the MPSC on reducing risk and ensuring patient safety

July 7 - The Organ Procurement and Transplantation Network (OPTN) Membership and Professional Standards Committee (MPSC) recently communicated several recommendations and opportunities for improvement in processes and protocols related to organ recovery and transplant related to managing multiple kidneys and reducing risk to ensure patient safety.

Verici releases results for Clarava, a kidney transplant rejection test

July 4 - Verici Dx, a developer of clinical diagnostics for organ transplant, has seen successful validation results from its prospective, blinded, clinical validation study for Clarava, a pre-transplant prognostic test to measure a patient’s immune response and assess the risk of early kidney transplant rejection. The test is based on RNA sequencing and uses artificial intelligence to work out an RNA signature from gene expression. Using just a simple blood draw, it will help clinicians to treat an estimated 65,000 eligible patients each year upon its commercial launch before the end of 2023.

Study: Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo

July 6 - Induced pluripotent stem (iPS) cells have a great impact on medicine and biology, and they are likely to shift the paradigm in regenerative medicine. Since 2014 when a sheet of retinal pigment epithelial cells derived from iPS cells was transplanted into patients with age-related macular degeneration, clinical trials have been conducted with various cell types derived from iPS cells.

Looking At Therapy Past Transplantation in Newly Diagnosed Multiple Myeloma

July 6 - A discussion on how to best treat patients with multiple myeloma after they undergo transplant and whether continuing quadruplet therapy can provide a benefit before maintenance therapy.

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Transplantation - Updates

Transplantation - Highlighted Tweets

Transplantation Direct - Highlighted Tweets

ISUTx 2023 - Registration is Now Open!

Join us for two days of engaging panel discussions, presentations, and networking with internationally-renowned faculty and researchers.

SPLIT 2023 - Early-bird Registration Deadline

Register Today and Save - Early-bird Registration Ends Tomorrow, July 15!

IPITA-IXA-CTRMS Joint Congress

Early-bird Registration Deadline: July 24
Take advantage of the reduced fees!

In the News

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study

Illegal organ trade is more sophisticated than one might think - who’s behind it and how it could be controlled

Clinical trial set to change kidney transplant practice

A first for UCLouvain in the fight against organ transplant rejection

USA - 11-month-old’s partial heart transplant makes history in Texas. How doctors did it

Girl receives heart of 4-year-old-boy in first transplant of its kind in Ukraine

Kidney transplantation surgeries to be carried out in Kyrgyzstan

First robotic liver transplant in U.S. performed by Washington University surgeons

USA - A UW Medicine team saved a patient with a dual-organ transplant based on a concept about immunoprotection.

An important message from the MPSC on reducing risk and ensuring patient safety

Verici releases results for Clarava, a kidney transplant rejection test

Study: Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo

Looking At Therapy Past Transplantation in Newly Diagnosed Multiple Myeloma

Upcoming Meetings and Announcements

CAST 2023

ISUTx 2023

SPLIT 2023

ISODP 2023

IPITA-IXA-CTRMS Joint Congress

TTS 2024

Social

Contact

Address

Info

Member Login

Transplantation - Updates

Transplantation - Highlighted Tweets

Transplantation Direct - Highlighted Tweets

ISUTx 2023 - Registration is Now Open!

Join us for two days of engaging panel discussions, presentations, and networking with internationally-renowned faculty and researchers.

SPLIT 2023 - Early-bird Registration Deadline

Register Today and Save - Early-bird Registration Ends Tomorrow, July 15!

IPITA-IXA-CTRMS Joint Congress

Early-bird Registration Deadline: July 24 Take advantage of the reduced fees!

In the News

Race-free estimated glomerular filtration rate equation in kidney transplant recipients: development and validation study

Illegal organ trade is more sophisticated than one might think - who’s behind it and how it could be controlled

Clinical trial set to change kidney transplant practice

A first for UCLouvain in the fight against organ transplant rejection

USA - 11-month-old’s partial heart transplant makes history in Texas. How doctors did it

Girl receives heart of 4-year-old-boy in first transplant of its kind in Ukraine

Kidney transplantation surgeries to be carried out in Kyrgyzstan

First robotic liver transplant in U.S. performed by Washington University surgeons

USA - A UW Medicine team saved a patient with a dual-organ transplant based on a concept about immunoprotection.

An important message from the MPSC on reducing risk and ensuring patient safety

Verici releases results for Clarava, a kidney transplant rejection test

Study: Transplantation of genome-edited iPS cells delivers therapeutic molecules in vivo

Looking At Therapy Past Transplantation in Newly Diagnosed Multiple Myeloma

Upcoming Meetings and Announcements

CAST 2023

ISUTx 2023

SPLIT 2023

ISODP 2023

IPITA-IXA-CTRMS Joint Congress

TTS 2024

Social

Contact

Address

Info

Early-bird Registration Deadline: July 24
Take advantage of the reduced fees!