Just Released - Transplantation - March Issue
This issue continues the current focus on perfusion systems to improve the use of donated organs, the combination of perfusion with gene therapies is reviewed, and utilization of virus-infected organs is studied, showing there is "HOPE". Allocation policies across many organs and patients with different risk factors are analyzed for their impact on both sides of the Atlantic. In summary, this is an issue of the times as we attempt to gain more for more people through transplantation.
Table of Contents
Around the World
Research Highlights
Game Changer
Meeting Report
Expert Insight
Meeting Notes
Commentaries
- Antibody-suppressing CD8+ T-cell Therapy for Antibody-mediated Rejection: Clinical Considerations
- Expanding the Donor Pool: Using Kidney and Heart Allografts From Hepatitis B–positive Donors
- A Call to Action: Furthering the Utilization of Technical Variants Pediatric Liver Transplantation Through Increased Awareness and Education
- Context Is Everything
- Transplanting Pediatric Candidates at an Optimal Time for Long-term Growth: Insights From an Asian Cohort
- Expanding Donor Criteria at What Cost?
- Donor Resuscitation Time, Kidney Transplant, and Selection Bias: Les reins ont des raisons que la raison ne connaît pas (with Apologies to Blaise Pascal)
Reviews
- Genetic Modulation: Future Trends Toward Graft Optimization During Machine Perfusion
- Strategies to Improve the Utilization and Function of DCD Livers
- The Impact of T-cell Aging on Alloimmunity and Inflammaging
- Radiomics in Kidney Transplantation: A Scoping Review of Current Applications, Limitations, and Future Directions
- Assessment and Evaluation of Alcohol Use Disorder in Liver Transplant
- Understanding Tricuspid Regurgitation Post Cardiac Transplantation; Why “Anatomical” and “Functional” Just Won’t Cut It
Original Basic Science
- Nuclear Matrix-associated Protein SMAR1 Attenuated Acute Graft-versus-host Disease by Targeting JAK-STAT Signaling in CD4+ T Cells
- Protein Phosphatase 2A Activation Promotes Heart Transplant Acceptance in Mice
- Intermittent Ex Vivo Lung Perfusion in a Porcine Model for Prolonged Lung Preservation
- CXCR5+CD8+ T Cell–mediated Suppression of Humoral Alloimmunity and AMR in Mice Is Optimized With mTOR and Impaired With Calcineurin Inhibition
Original Clinical Science—Liver
- Use and Outcomes of Hepatitis B Virus-positive Grafts for Kidney or Heart Transplantation in the United States From 1999 to 2021
- Technical Variant Liver Transplant Utilization for Pediatric Recipients: Equal Graft Survival to Whole Liver Transplants and Promotion of Timely Transplantation Only When Performed at High-volume Centers
- Living Donor Liver Transplantation for Adults With High Model for End-stage Liver Disease Score: The US Experience
- Differential Impact of the UNOS Simultaneous Liver-kidney Transplant Policy Change Among Patients With Sustained Acute Kidney Injury
- Long-term Catch-up Growth and Risk Factors for Short Adult Height After Pediatric Liver Transplantation: A Retrospective Study
- Alcohol Use in Liver Transplant Recipients With Alcohol-related Liver Disease: A Comparative Assessment of Relapse Prediction Models
Original Clinical Science—General
- Later Brain Death Declaration Correlates to Favorable Donor Characteristics but Decreased Heart Acceptance
- Wait Time Advantage for Transplant Candidates With HIV Who Accept Kidneys From Donors With HIV Under the HOPE Act
- Effect of Cardiac Arrest in Brain-dead Donors on Kidney Graft Function
- A Pilot Randomized Controlled Trial of De Novo Belatacept-based Immunosuppression After Lung Transplantation
- Improving the Access of Highly Sensitized Patients to Kidney Transplantation From Deceased Donors: The Spanish PATHI Program With Allocation Based on the Virtual Crossmatch
- Representation of Women Authorship in the Top 5 Transplantation Journals in the United States
TTS 2024 - Registation and Hotel Reservations now open!
Registration now open!
Register today and take advantage of the early bird rate!
We have both in-person and virtual options with the in-person fee including access to all sessions, recordings, lunches, coffee breaks and opening ceremonies.
To maximize attendance we have deeply discounted fees for fellows, trainees, AHP's and those from Low to Middle Income Countries (LMIC).
Hotels
We reserved a wide variety of hotels at different price points for attendees. Supply is limited so we recommend you book early.
Travel
Turkish Airlines, our official partner, is offering a 15% discount in economy class and 20% in business class flights.
Thematic Session - Genetics in precision medicine
Monday September 23, 2024 | 15:40 to 16:40
Shane T Grey, Australia
Genetics for precision medicine in transplantation
Jasper Callemeyn, Belgium
Biopsy transcriptomics for diagnosis and research
Sophie Brouard, France
Identifying operational tolerance
Thematic Session - Organ perfusion and preservation
Tuesday September 24, 2024 | 15:40 to 16:40
Emily R. Thompson, UK
Novel delivery of cellular therapy to reduce ischemia reperfusion injury in kidney transplantation
Gabriel Oniscu, Sweden
Ex-situ machine perfusion (heart, liver, kidney) (standard, oxygenated, hypothermic, normothermic)
Erik Finger, United States
Cryopreservation
Submitting an abstract to the TTS 2024 Congress offers a platform to showcase groundbreaking research, connect with global experts, and contribute to advancements in transplantation medicine, fostering collaboration and influencing the field's future direction.
Submission Deadline: March 18, 2024.
2024 Scientific Congress Awards
The TTS scientific congress awards are designed to help offset expenses incurred to attend the TTS congress in Istanbul (in-person ONLY) and are awarded based on the scientific merit of the applicants.
To be eligible, an individual must:
- Submit an abstract to TTS 2024 as presenting author
- Be a member in good standing of TTS
- Be a trainee/fellow/PhD student OR Allied health professional OR resident of emerging economy nation
Award Application Deadline: April 26, 2024
2024 Mentee-Mentor Awards
The Transplantation Society, in collaboration with National and International Societies acknowledges the contribution of basic science to the field of transplantation by offering Mentee-Mentor awards.
International Basic and Translational Science Mentee-Mentor Awards
TTS-ISOT La Renon International Basic and clinical sciences Mentee-Mentor Awards
Award Application Deadline: April 26, 2024
Transplantation Journal Highlights
Transplantation - Social Media Content
T-B Collaboration in Autoimmunity, Infection, and Transplantation
We have attempted here to provide an up-to-date review of the collaboration between helper T cells and B cells in response to protein and glycoprotein antigens. This collaboration is essential as it not only protects from many pathogens but also contributes to a litany of autoimmune and immune-mediated diseases.
Outcomes of Kidney Transplantation in Patients That Underwent Bariatric Surgery: A Systematic Review and Meta-analysis
The impact of bariatric surgery (BS) on kidney transplantation (KT) outcomes in patients with obesity remains controversial. We systematically searched MEDLINE, EMBASE, Scopus, Web of Science, and Cochrane Central Register of Controlled Trials for studies reporting outcomes of KT recipients that underwent prior BS. Common/random effects meta-analyses were performed to obtain summary ratios of the postoperative outcomes.
Transplantation Direct - Social Media Content
Trabecular Bone Score Improves Early After Successful Kidney Transplantation Irrespective of Antiresorptive Therapy and Changes in Bone Mineral Density
Trabecular bone score (TBS) is a new tool to assess trabecular bone microarchitecture based on standard dual-energy x-ray absorptiometry (DXA) of lumbar spine images. TBS may be important to assess bone quality and fracture susceptibility in kidney transplant recipients (KTRs). This study aimed to investigate the effect of different bone therapies on TBS in KTRs.
Canadian Kidney Transplant Professionals’ Perspectives on Precision Medicine and Molecular Matching in Kidney Allocation
Antibody-mediated rejection is an important cause of kidney transplant loss. A new strategy requiring application of precision medicine tools in transplantation considers molecular compatibility between donors and recipients and holds the promise of improved immunologic risk, preventing rejection and premature graft loss. The objective of this study was to gather Canadian transplant professionals’ perspectives on molecular compatibility in kidney transplantation.
Upcoming Webinars
Program Update - March 6-7 Pediatric Symposium
Pediatric Symposium
International Symposium on Pediatric Organ Donation & Transplantation
Contact
Address
The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada