TTS 2024 Newsletter #1 - Calling all Transplantation Enthusiasts and Medical Innovators
As the Istanbul Congress approaches, we are committed to keeping the transplant community well-informed about the latest developments through a series of TTS 2024 Newsletters
This inaugural edition offers a comprehensive overview of the entire congress, and forthcoming issues will delve into specific sessions, themes, and noteworthy features. Stay tuned for in-depth insights into the upcoming event.
Just Released - Transplantation Direct - March Issue
The March issue of Transplantation Direct covers a broad cross-section in transplantation. Topics covered in kidney transplantation include microbiota diversity effects, B cell antigen presentation and rejection, significance of high EBV loads, use of extracorporal photopheresis, IgM DSA implications, urinary endotrophin as a biomarker, as well as CAR T cell therapy for PTLD and optimizing analgesia for live-donor nephrectomies. Topics in liver transplantation explored involve portopulmonary hypertension treatment in waiting-list patients, implications of sarcomatoid hepatocellular carcinoma, and CXCL8 as a biomarker of graft injury. In lung transplantation, there are articles on a surgical technique to avoid atrial fibrillation after transplantation, diagnosis and treatment of esophageal fistulas, transplantation for pulmonary AL amyloidosis, and a report on attitudes of recipients regarding pregnancy and parenthood. For those involved in heart transplantation, there is a study on risk factors related to severe acute kidney injury after allografting. On the topic of organ donation, an observational study explores still-existing disparities among Hispanic patients awaiting transplantation. We welcome you to visit our Transplantation Direct website for full and free open access to all of these articles.
Table of Contents
Kidney Transplantation
- Effectiveness of Postoperative Single-shot and Continuous Transverse Abdominis Plane Block Compared to Conventional Analgesia in Hand-assisted Laparoscopic Live-donor Nephrectomy
- Distinct Changes in Gut Microbiota of Patients With Kidney Graft Rejection
- Urinary Endotrophin and Long-term Outcomes in Kidney Transplant Recipients
- CAR T-Cell Therapy for Refractory Posttransplantation Lymphoproliferative Disorder in a Kidney Transplant Patient
- Assessment of IgM DSAs in Transplant Recipients: Relationship to De Novo IgG DSAs and Risk for Antibody Rejection
- Extracorporeal Photopheresis Reduces Fibrotic and Inflammatory Transcriptomic Biological Marker of Chronic Antibody-mediated Kidney Rejection
- Epidemiology of Epstein-Barr Virus Chronic High Viral Load in Kidney Transplant Recipients
Liver Transplantation
- The Clinical Course of Portopulmonary Hypertension and Outcomes With Endothelin Receptor Antagonist Treatment: Observational Study of Data From the US Organ Procurement and Transplantation Network
- Rapidly Progressive Pulmonary Lymphangitic Carcinomatosis After Liver Transplantation Due to Diffuse Infiltrative Sarcomatoid Hepatocellular Carcinoma
- Elevated Plasma CXCL8 Concentrations in Significant Fibrosis but Not in Subclinical Rejection After Adult Liver Transplantation
Lung Transplantation
- Practicality and Safety of Electrical Pulmonary Vein Isolation and Left Atrial Appendage Ligation in Lung Transplant Recipients With Pretransplant Atrial Fibrillation
- Practice Patterns and Attitudes Regarding Pregnancy and Parenthood After Lung Transplantation
- Diagnosis and Management of Esophageal Fistulas After Lung Transplantation: A Case Series
- Lung Transplantation for Pulmonary AL Amyloidosis
Heart Transplantation
Ethics
Erratum
TTS 2024 - Abstract Deadline is less then 2 weeks away!
2024 Scientific Congress Awards
To be eligible, an individual must:
- Submit an abstract to TTS 2024 as presenting author
- Be a member in good standing of TTS
- Be a trainee/fellow/PhD student OR Allied health professional OR resident of emerging economy nation
The TTS scientific congress awards are designed to help offset expenses incurred to attend the TTS congress in Istanbul (in-person ONLY) and are awarded based on the scientific merit of the applicants.
Award Application Deadline: April 26, 2024
2024 Mentee-Mentor Awards
The Transplantation Society, in collaboration with National and International Societies acknowledges the contribution of basic science to the field of transplantation by offering Mentee-Mentor awards.
International Basic and Translational Science Mentee-Mentor Awards
TTS-ISOT La Renon International Basic and clinical sciences Mentee-Mentor Awards
Award Application Deadline: April 26, 2024
TTS 2028 Congress - Call for Expressions of Interest
Deadline to submit your expression of interest is March 28, 2024
Based on regional rotation, The Transplantation Society (TTS) plans to hold its 2028 TTS Biennial Congress in East, South or Southeast Asia. The Congress is anticipated to be held over 4 to 5 days – Saturday/Sunday to a Wednesday.
TTS welcomes interested societies to submit an expression of interest (EOI) to host the 32nd International Congress of The Transplantation Society in 2028. TTS IHQ will then work with shortlisted Host Societies (HS) to collect the information required for Council’s consideration and approval.
The Congresses are major undertakings and will require extensive planning, preparation and collaboration between TTS and local hosts. Given the Society's Congresses attract 3,000 – 4,500 registrants recommended venues must accommodate up to 4,000 delegates.
2024 Education Committee Webinar Series
In collaboration with the various Committees and Sections of the Society, the Education Committee is proud to present a series of educational webinars that have been specially designed for the whole TTS membership. The series has been carefully curated with the aim of addressing a wide range of topics, and drawing on diverse expertise and perspectives from around the world. Covering ethical controversies, cutting edge science, and fundamental challenges in policy-making and clinical care for transplant recipients and donors, we hope the program will provide valuable and engaging opportunities for all members to advance their knowledge and skills.
Click an image below to visit the individual webinar page.
CME Accredited Online Ecucation Activity: Cytomegalovirus (CME)
Third-party educational activity (not developed by TTS) but open to the TTS community.
Join Drs. Kotton, Pereira, and Razonable as they discuss the management of cytomegalovirus (CMV) infection in solid organ transplant (SOT) patients. Topics covered include treatment challenges, laboratory testing, and new therapy for refractory or resistant CMV.
ISN-TTS Sister Transplant Centers Program
Research Grants Program - Letter of Intent Deadline: April 30th, 2024
Transplantation Journal Highlights
Transplantation - Social Media Content
The Promise of Complement Therapeutics in Solid Organ Transplantation
Transplantation is the ideal therapy for end-stage organ failure, but outcomes for all transplant organs are suboptimal, underscoring the need to develop novel approaches to improve graft survival and function. The complement system, traditionally considered a component of innate immunity, is now known to broadly control inflammation and crucially contribute to induction and function of adaptive T-cell and B-cell immune responses, including those induced by alloantigens.
Marginal Zone B Cells Are Necessary for the Formation of Antidonor IgG After Allogeneic Sensitization
The formation of anti–major histocompatibility complex (MHC) antibodies is a significant barrier for many patients awaiting organ transplantation. Patients with preformed anti-MHC antibodies have limited options for suitable donors, and the formation of donor-specific anti-MHC antibodies after transplantation is a harbinger of graft rejection. Despite the recognized importance of anti-MHC antibodies, the mechanisms responsible for the differentiation of B cells after exposure to allogeneic antigens are poorly understood.
Transplantation Direct - Social Media Content
Continuous Renal Replacement Therapy During Long-term Normothermic Machine Perfusion of Human Donor Livers for up to 7 D
Normothermic machine perfusion (NMP) is used to preserve and test donor livers before transplantation. During NMP, the liver is metabolically active and produces waste products, which are released into the perfusate. In this study, we describe our simplified and inexpensive setup that integrates continuous renal replacement therapy (CRRT) with NMP for up to 7 d. We also investigated if the ultrafiltrate could be used for monitoring perfusate concentrations of small molecules such as glucose and lactate.
The Use of Ex Situ Normothermic Machine Perfusion in Combined Cardiac and Liver Transplantation Procedures
Combined heart-liver transplantation (CHLT) is a complex procedure that treats multiorgan disease and organ failure. CHLT has become increasingly common in recent years because of advancements in surgical techniques and immunosuppression.The most common indications for CHLT include familial amyloidosis, cardiac cirrhosis caused by congenital heart disease and dilated cardiomyopathy, and homozygous familial hypercholesterolemia.Additionally, with the aging population, the need for cardiac interventions such as coronary artery bypass surgery in combination with liver transplantation is becoming increasingly common.There are several major challenges to the CHLT procedure, including hemodynamic instability following implantation and prolonged cold ischemia during organ preservation when managing the logistics of dual organ implantation or surgery.
Upcoming Webinar Presentations
Click an image below to visit the indiviual webinar page.
Guy Alexandre, Transplant Surgeon Who Redefined Death, Dies at 89
His willingness to remove kidneys from brain-dead patients increased organ viability while challenging the line between living and dead.
Guy Alexandre, a Belgian transplant surgeon who in the 1960s risked professional censure by removing kidneys from brain-dead patients whose hearts were still beating — a procedure that greatly improved organ viability while challenging the medical definition of death itself — died on Feb. 14 at his home in Brussels. He was 89.
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