The June issue of Transplantation Directjam-packed with articles on a wide-variety of topics affecting different transplanted organs including kidney, liver, heart, pancreas, intestine, multi-organ, VCA, and others. Just to name a few themes, infectious disease topics are covered related to CMV, EBV, HIV, hepatitis E and cryptococcus, as well as COVID vaccination. There are overviews on the urobiome, left ventricular hypertrophy in kidney transplantation and the use of cytopheric devices for pre-transplant bridging. Machine perfusion studies are represented, and also various studies on surgical aspects of transplantation related to intestinal/multi-organ surgeries, new techniques in HCC liver transplant recipients, and an assessment of surgical complications after kidney transplantation. Organ donation topics include articles on organ underutilization, live donor mental health, variations in DCD liver transplant protocols in the U.S., improved treatments of uDCD kidneys for transplantation, and organ access for small recipients. This is just a sampling of topics to highlight, so please visit our open-access Transplantation Direct website for full details of these and other articles of interest.