Just Released - Transplantation Journal - January 2025 Issue
The January issue highlights a series of articles that summarize the high-level deliberations of the Santander meeting. This meeting brought together an international group of experts for a summit paving the way forward in organ transplantation. This article series covers the entire spectrum of organ donation and transplantation, discussing the global challenges that we face while offering guidance on how to move forward. The role of AI in transplantation, aging, and organ allocation are additional clinical highlights with basic research reporting on updates of organ preservation and the generation of scalable stem cell-derived islets. Don’t miss the first issue of 2025!
Table of Contents
Editorial
Expert Insights
- Santander Global Summit in Transplantation: Supporting Global Convergence in the Shared Goals of Sufficiency, Transparency, and Oversight
- Santander Statement: Towards Global Convergence in Transplantation: Sufficiency, Transparency, and Oversight
- Developing and Expanding Deceased Organ Donation to Its Maximum Therapeutic Potential: An Actionable Global Challenge From the 2023 Santander Summit
- Expanding Opportunities for Living Donation: Recommendations From the 2023 Santander Summit to Ensure Donor Protections, Informed Decision Making, and Equitable Access
- Promoting Equitable and Affordable Patient Access to Safe and Effective Innovations in Donation and Transplantation of Substances of Human Origin and Derived Therapies
- Supporting Financial Neutrality in Donation of Organs, Cells, and Tissues
- Toward Equity in Global Access to SoHO-based Therapies: Recommendations for Action
- Reinforcing Global Oversight of Organ Transplantation: Activity and Outcome Monitoring Through the Development of Registries
- Transplantation: A Priority in the Healthcare Agenda
- Prevention of Trafficking in Organs, Tissues, and Cells
Research Highlights
Commentaries
- Waitlist Time, Age, and Social Vulnerability: Impact on the Survival Benefit of Deceased Donor Kidney Transplantation Versus Long-term Dialysis Among Patients With End-stage Renal Disease
- “Out With the Old, In With the New”: Donor Risk Evolution Is Upon Us
- Modeling Broader Liver Sharing Allocation: Promise and Pitfalls
- A Liver Graft Should Not Be Selected by the Side but Determined by Volume in Adult Living Donor Liver Transplantation
Reviews
- Understanding the Healthcare Needs of Living Kidney Donors Using the Picker Principles of Patient-centered Care: A Scoping Review
- Cherry on Top or Real Need? A Review of Explainable Machine Learning in Kidney Transplantation
- Age Is Just a Number for Older Kidney Transplant Patients
- Tacrolimus-loaded Drug Delivery Systems in Vascularized Composite Allotransplantation: Lessons and Opportunities for Local Immunosuppression
Original Basic Sciences
- An Enhanced Role of Innate Immunity in the Immune Response After Kidney Transplant in People Living With HIV: A Transcriptomic Analysis
- Pancreas Preservation: Hypothermic Oxygenated Perfusion to Improve Graft Reperfusion
- Exercise Preconditioning of the Donor Liver Decreases Cold Ischemia/Reperfusion Injury in a Mouse Model
- Oxidized ATP Suppresses B Lymphocyte Activity to Attenuate Antibody-mediated Rejection of Kidney Allografts in Mice
- Scalable Bioreactor-based Suspension Approach to Generate Stem Cell–derived Islets From Healthy Donor-derived iPSCs
Original Clinical Science—Liver
- Liver Retransplantation Using Living Donor Grafts: A Feasible Approach for Chronic Allograft Failure
- Outcomes of Liver Transplantation From Hepatitis C Virus–positive DCD Donors and Its Utilization Among Centers in the United States
- Targeted Broader Sharing for Liver Continuous Distribution
- Comparison of Clinical Outcomes Using Left and Right Liver Grafts in Adult-to-adult Living-donor Liver Transplantation: A Retrospective Cohort Study Using the Korean Organ Transplantation Registry
- Transarterial Radioembolization Can Downstage Intermediate and Advanced Hepatocellular Carcinoma to Liver Transplantation
Original Clinical Science—General
- Waitlist Time, Age, and Social Vulnerability: Impact on the Survival Benefit of Deceased Donor Kidney Transplantation Versus Long-term Dialysis Among Patients With End-stage Renal Disease
- Systematic Reporting of Eosinophils in Transbronchial Biopsies After Lung Transplantation Defines a Distinct Inflammatory Response
- Islet Isolation Outcomes in Patients Undergoing Total Pancreatectomy With Islet Autotransplantation in the POST Consortium
Letters to the Editor
- Comment on: HPi: A Novel Parameter to Predict Graft-related Outcome in Adult Living Donor Liver Transplant. What Have We Missed?
- Bile Chemistry During Ex Situ Normothermic Liver Perfusion Does Not Always Predict Cholangiopathy
- Sustained Absence of Perfusion to the Brain Must Be Ensured During Thoracoabdominal Normothermic Regional Perfusion
Abstract Submission for WTC 2025 is Now Open!
Membership Renewals
Membership renewal notices for TTS and Section Members were sent out December 6th.
If you are a member please log into your account to pay your dues and update your profile.
Click here for details: https://tts.org/member-area/member
Transplantation Journal Highlights
Transplantation - Social Media Content
Another Viral Infection Linked to Posttransplant Diabetes Mellitus?
In this issue of Transplantation, Vinson et al1 published a large retrospective study incorporating data from the largest data repository for patients with COVID-19 in the United States, the N3C COVID Enclave, which includes 83 medical centers. They examined nondiabetic adult solid organ transplant recipients (SOTRs) between April 1, 2020, and March 31, 2023, with a minimum follow-up time of 6 mo. To evaluate the risk of developing posttransplant diabetes mellitus (PTDM), the authors compared those who developed COVID-19 within the first 180 d after transplantation with those who did not.
Basiliximab Induction and Postoperative Steroid-free Immunosuppression With Tacrolimus in Pediatric Liver Transplantation: A Randomized Clinical Trial
Optimizing the immunosuppressive regimen is essential to improve the long-term outcomes of pediatric liver transplant recipients.
Transplantation Direct - Social Media Content
Dynamics of Ischemia/Reperfusion Injury Markers During Normothermic Liver Machine Perfusion
A comprehensive mechanistic assessment of normothermic machine perfusion (NMP) is an essential step toward identifying biomarkers to assess liver viability. Although some studies have evaluated the effect of NMP on inflammation markers, there are other key pathological mechanisms involved in ischemia/reperfusion injury (IRI) that have not yet been evaluated.
Risk Stratification Before Living Donor Kidney Transplantation in Patients With Preformed Donor-specific Antibodies by Different Crossmatch Methods
Preformed donor-specific HLA antibodies (DSA) are a well-known risk factor in kidney transplantation. There is still considerable debate, however, about the optimal risk stratification among patients with preformed DSA. Additionally, data on the prognostic value of different crossmatch assays in DSA-positive patients are scarce.
Upcoming Webinar Presentation
In the News
IPITA 2025
19th Congress of the International Pancreas and Islet Transplant Association
ISUTx 2025
5th State-of-the-Art Meeting of the International Society of Uterus Transplantation
ISODP 2025
17th Organ Donation Congress
Contact
Address
The Transplantation Society
International Headquarters
740 Notre-Dame Ouest
Suite 1245
Montréal, QC, H3C 3X6
Canada