The February issue of Transplantation Direct is out! Many topics are covered in this issue, starting with kidney transplantation reporting on gene-based guidance for personalized immunosuppression (precision therapy), defining safe levels of anti-A2 titers in A2 incompatible transplants, the impact of subclinical borderline inflammation on long-term outcomes, use of donor cf-DNA to detect rejection in recipients being treated with check-point inhibitors (posttransplant malignancy), and assessment of a Spanish-language “fear of kidney failure questionnaire"; we also have an experimental (pig) study testing use of short oxygenated hypothermic machine perfusion before normothermic perfusion in injured kidneys, and a study on effects of residual kidney function on outcomes in kidney transplants combined with either liver or heart transplantation. In liver transplantation, there are reports on using transplantation in cases of locally advanced undifferentiated embryonal cell sarcoma, managing pain using thoracic epidural analgesia, using the splenic artery transposition technique, and comparing waitlist mortality predictability using “liver frailty index" vs. “Karnofsky performance status"; there are also case study reports on the topics of protein-losing enteropathy and on liver transplant “only" decisions in patients with liver failure and heart disease. Regarding other transplants, we have articles on peri-operative desensitization strategies in heart transplantation, and an experimental study in non-human primates on the influence of vascularized bone marrow transplants with vascularized composite allografts; finally, a comprehensive review on lung ischemia reperfusion injury mechanisms, including current and future treatment options. For further details, accessible by open-access, please visit our Transplantation Directwebsite.
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Dear Women in Transplantation and TTS members,
The Asian Society of Transplantation (AST - myasot.org) in collaboration with the TTS Women in Transplantation (WIT) initiative are hosting two webinars on Gender Disparity in Transplant in Asia.
Thursday February 25th 2021 (19:00 Seoul / Tokyo time - GMT+9)
Women in Transplantation (WIT) initiative of The Transplantation Society will provide funding to an Early Career Researcher to support research focusing on sex and gender issues relevant to solid organ transplantation.
The spectrum of studies includes basic, clinical and translational. This individual should have spent two years or less performing research relevant to solid organ transplantation since obtaining their last degree (PhD, MD, MSc, PharmD, or equivalent). This work may represent a continuation of current research or a novel aspect of work. The mentor should have expertise in transplantation or immunology but need not be an investigator with known expertise in gender or sex.
This initiative was made possible with support with One Lambda, a Thermo Fisher Scientific brand, and Sanofi, with each supporting one award.
Feb. 3 - A surgical team from NYU Langone Health performed a face and double hand transplant for a 22-year-old New Jersey resident severely burned in a horrific car crash. The surgery included transplanting both hands and the full face of a single donor. It marked the first successful combination transplant case of its kind in the world.
Feb. 2 - Prioritize people who need the organs urgently—or those who will live longest because of them?
Feb. 2 - Young, Black adults are more than twice as likely to die in the first year after a heart transplant when compared to same-age, non-Black heart transplant recipients, according to new research published today in Circulation: Heart Failure, an American Heart Association journal.