TTS 2024 - October 21-23 Virtual Program

Virtual Program Details

The Congress Webapp (app.tts2024.org) combines both the live and virtual agendas as well as congress recordings, click the button below for the full program. TTS 2024 delegates may login with the same email and password used at the Congress.

Important Announcement - Member Virtual Access

TTS Members may view the October 21-23 live virtual sessions for no fee. Simply visit our homepage (www.tts.org) on the first day of the virtual event, login into your member account and you will have access to view the sessions. An email will be sent to the membership in the week leading up to the event with further details.

TTS 2024 Virtual Registration for Non-Members

Includes recordings from September 22-25 and upcoming live virtual sessions from October 21-23!

Member Access to TTS 2024 Recordings

We are excited to announce that all TTS members now have exclusive access to the recordings from the TTS 2024 Congress. Whether you were able to attend in person or not, this is a fantastic opportunity to revisit key presentations, explore groundbreaking research, and deepen your understanding of the latest advances in transplantation science. These recordings are available for your ongoing professional development and to help you stay current with the most important trends and innovations in our field. We hope you find them valuable as a resource for your continued learning and engagement with the global transplantation community.
TTS 2024 Congress Recording Sponsored by:

WTC 2025 - Deadline was October 11 however we are accepting submissions over the weekend!!
Needs Assessment Survey & Call For Program Sessions

WTC 2025 Needs Your Opinion

We are seeking your valuable input to improve the upcoming 2025 World Transplant Congress. We would greatly appreciate your participation in a short (8min) Needs Assessment Survey. You can access the survey by clicking on the button “Survey Link” below. The deadline to complete was October 11, 2024, at 11:29 pm (EST) however we are accepting submissions over the weekend.

Please note that you are not required to complete the entire survey. Feel free to provide input on the sections that are the most relevant to you. Your responses will be incredibly helpful, even if you choose to answer just a few questions.

Thank you for your time and insights!

The WTC 2025 Organizing Committee

WTC 2025 - Call for Sessions

On behalf of the American Society of Transplantation, the American Society of Transplant Surgeons, and The Transplantation Society, we are delighted to invite you to submit your ideas for program sessions for the World Transplant Congress 2025 (WTC 2025), to be held from August 2-6, 2025, in San Francisco, California, USA.

We are looking for programs that will be interactive, include global themes, speakers, and moderators, and focus on cutting-edge topics that address transplantation and end organ failure.


Just Released - Transplantation Direct - October Issue

The October Transplantation Direct issue is ready for viewing. Many aspects of transplantation are covered in this issue including the area of organ donation where outcomes following changes in HTLV screening practice in the US are evaluated, and the influence of using procurement teams not affiliated with recipient centers on DCD liver transplant outcomes. We have an article on textbook outcomes in organ transplantation being proposed for quality benchmarking. Patients in need of a bioartificial pancreas are explored in another paper. In liver transplantation, a critical analysis has been done on recipients over 75 years old, and another article looks at performing liver transplants in patients with portopulmonary hypertension. A new GFR calculation is proposed to evaluate living donors in kidney transplantation, and the impact of induction therapy and high-risk viral discordance in the USA is determined in older kidney recipients. For our pediatric and heart experts, we have an article on using ddcfDNA measurements as a predictor in pediatric heart transplant recipients. In addition, for those interested in composite tissue transplantation, molecular signatures associated with acute rejection are explored. Please visit our Transplantation Direct website for all the details on these and other articles, all which are freely available to everyone by open access.



Transplantation Journal Highlights

Transplantation and Transplantation Direct - Editors at TTS 2024 Istanbul Congress

The editors of Transplantation and Transplantation Direct met with TTS 2024 attendees during an interactive round-the-table session, to discuss the future of both journals, including what is important in a submission, what are the current hot topics, why authors should publish in both journals, and what the journals offer to authors and readers.
Key aspects are:
  • global readership
  • expert review
  • rapid publication
  • strong social media promotion
The editors look forward to receiving your best research submissions.
Executive Editors, Carla Baan and Stefan G. Tullius; Editor-in-Chief, Jeremy R. Chapmans; Social Media Editor, Macey L. Levan
Deputy Editor, Fadi Issa; Social Media Editor, Macey L. Levan; Executive Editors, Stefan G. Tullius and Edward K. Geissler; Associate Editor, Jennifer Li; Executive Editor, Carla C. Baan; Associate Editor, Xunrong Luo

Transplantation - Social Media Content

Pharmacomicrobiomics: Immunosuppressive Drugs and Microbiome Interactions in Transplantation
The human microbiome is associated with human health and disease. Exogenous compounds, including pharmaceutical products, are also known to be affected by the microbiome, and this discovery has led to the field of pharmacomicobiomics. The microbiome can also alter drug pharmacokinetics and pharmacodynamics, possibly resulting in side effects, toxicities, and unanticipated disease response. Microbiome-mediated effects are referred to as drug–microbiome interactions (DMI).
Mechanistic Understanding of EBV+Lymphoproliferative Disease Development After Transplantation
Posttransplant lymphoproliferative disorders (PTLDs) are among the most common malignant complications after transplantation, leading to a drastic reduction in patient survival rates. The majority of PTLDs are tightly linked to Epstein-Barr virus (EBV+PTLDs) and are the result of an uncontrolled proliferation of EBV-infected cells. However, although EBV infections are a common finding in transplant recipients, most patients with high EBV loads will never develop EBV+PTLD.

Transplantation Direct - Social Media Content

Risk Stratification Before Living Donor Kidney Transplantation in Patients With Preformed Donor-specific Antibodies by Different Crossmatch Methods
Preformed donor-specific HLA antibodies (DSA) are a well-known risk factor in kidney transplantation. There is still considerable debate, however, about the optimal risk stratification among patients with preformed DSA. Additionally, data on the prognostic value of different crossmatch assays in DSA-positive patients are scarce.
Impact of Intrapatient Immunosuppression Variability in Liver Transplantation Outcomes: A Systematic Review and Meta-analysis
To investigate the impact of intrapatient variability (IPV) in the levels of immunosuppressant drugs on health outcomes after liver transplantation, a comprehensive systematic review and meta-analysis were conducted.

5th Summit on Stem Cell Derived Islets - Online Registration Closes October 22nd!

Join 200 delegates and speakers representing leading experts and key opinion leaders in the field!

The International Pancreas and Islet Transplant Association (IPITA), the Harvard Stem Cell Institute (HSCI), and Breakthrough T1D (formerly JDRF) are hosting the 5th Summit on Stem Cell-Derived Islets at the Joseph B. Martin Conference Center in Boston, MA, USA, from October 28-29, 2024. This Summit will highlight the latest breakthroughs in stem cell-derived islet biology and complementary technologies, alongside showcasing the progress of clinical trials in this cutting-edge field. The program will feature presentations from world-renowned experts, offering insights into groundbreaking science and state-of-the-art advancements.

   Click here to View the Detailed Program
Monday, October 28, 2024
  • 07:00

    Registration opens
  • 08:00-08:15

    Welcome and Introductory Comments
    Welcome from: Jon Odorico and James Markmann
  • 08:15-09:30

    Session 1
    Insights from Islet Biology for Making Stem Cell-Derived Islets
    Moderator: Albert Hwa
  • 08:15-08:30

    Insights into islet biology from the human pancreas and beyond
    Alvin Powers, Vanderbilt University, United States
  • 08:30-08:45

    Insights into beta cell development from stem cells
    Matthias Hebrok, Technical University of Munich, Germany
  • 08:45-09:00

    Using stem cell islets to gain insights into human pancreas development
    Danwei Huangfu, Memorial Sloan Kettering, United States
  • 09:00-09:15

    Using human pancreas slices to understand islet physiology and function
    Joana Collares Pereira Almaca, University of Miami School of Medicine, United States
  • 09:15-09:30

    Panel Discussion
  • 09:30-10:00

    Coffee Break
  • 10:00-11:15

    Session 2
    Optimizing Differentiation to Stem Cell Beta Cells
    Moderator: Cristina Nostro
  • 10:00-10:15

    Tuning developmental signaling during stem cell-derived islet differentiation
    Nathaniel Hogrebe, Washington University School of Medicine, United States
  • 10:15-10:30

    Functional maturation of stem cell islets
    Diego Balboa, University of Helsinki, Finland
  • 10:30-10:45

    Origin and development of off-target cell populations arising during stem cell to islet differentiation
    Christian Honoré, Cell Therapy R&D, Novo Nordisk A/S, Denmark
  • 10:45-11:00

    Scalable generation of 3D stem cell islet organoids or Hallmarks and triggers of beta cell maturation
    Juan Alvarez-Dominguez, University of Pennsylvania, United States
  • 11:00-11:15

    Panel Discussion
  • 11:15-11:30

    Stretch Break
  • 11:30-12:45

    Session 3
    Immunology of T1D
    Moderator: Lorenzo Piemonti
  • 11:30-11:45

    Type 1 diabetes as a disease of the beta-cell
    Bart Roep, Leiden University Medical Center, Netherlands
  • 11:45-12:00

    Neoantigens and autoimmunity triggering mechanisms
    Eddie James, Benroya Research Institute, United States
  • 12:00-12:15

    Tracking antigen-specific T cell receptors during T1D progression
    Maki Nakayama, University of Colorado, United States
  • 12:15-12:30

    Modeling the immune infiltration of human stem cell-derived islets in vivo
    Remi Creusot, Columbia University, United States
  • 12:30-12:45

    Panel Discussion
  • 12:45-13:45

    Lunch Break, Poster Viewing & Group Photo
  • 13:45-14:15

    Keynote Address
    Introduction: Doug Melton
  • 13:45-14:15

    Disease Modifying Therapies and rationale for combining with stem cell islets
    Tom Kay, St Vincent's Hospital, Australia
  • 14:15-15:15

    Session 4A
    Best Abstracts Session I
    Moderator: Antonio Citro
  • Abstract 1

    Anja Ivis
    Strategies for preventing the formation of cytotoxic IAPP amyloid in human stem cell-derived islets
  • Abstract 2

    Hong Qian
    Development of a biovascular pancreas to deliver stem cell-derived islets as a therapy for type 1 diabetes
  • Abstract 3

    Anup Nair
    Modeling the effects of early hyperinsulinemia due to the R1420H SUR1 mutation using isogenic iPSC derived pancreatic Islets
  • Abstract 4

    Sophia Kioulaphides
    Human stem cell-derived beta-cells delivered with vasculogenic hydrogels reverse hyperglycemia in diabetic immunodeficient mice
  • Abstract 5

    Veronica Cochrane
    SC-beta cell MafA expression: for better or worse
  • Abstract 6

    Paraish Misra
    Islet versus enterochromaffin lineage allocation of hPSC-derived pancreatic progenitors can be modulated at both pre-progenitor and post-progenitor stages
  • 15:15-15:45

    Coffee Break
  • 15:45-16:45

    Session 4B
    Best Abstracts Session II
    Moderator: Tom Kay
  • Abstract 1

    Pere Catala
    Ultrafast Volumetric Bioprinting of an Endocrine Pancreas Using Functional Human iPSC-Derived Islets
  • Abstract 2

    Francesco Campo
    Bio-fabrication of a Human iPSC-based vascularized endocrine pancreas for the treatment of Type 1 Diabetes
  • Abstract 3

    Saleth Dharmaraj
    A perfusable encapsulation device housing Stem cell derived pseudo-islets to treat type-1 diabetes
  • Abstract 4

    Ji Lei
    Identifying optimal engraftment sites for human stem cell-derived islets in a non-Human primate model
  • Abstract 5

    Nicole Wojcik
    Optimization of immunosuppression for beta cell replacement therapy: assessing the tolerability and efficacy of belatacept combined with reduced tacrolimus
  • Abstract 6

    Daniel Tremmel
    Islet vascularized ECM organoid (IVEO) constructs repair isolated islets native environment for successful engraftment and functionality post-transplantation
  • 16:45-18:00

    Session 5
    Immune Evasive Islets
    Moderator: Holger Russ
  • 16:45-17:00

    PIDO induced islet immune protection from allo and xeno immunity
    Jacques Galipeau, University of Wisconsin School of Medicine and Public Health, United States
  • 17:00-17:15

    Hypoimmune Stem Cell Islets
    Sonja Schrepfer, Sana Biotechnology, United States
  • 17:15-17:30

    Genome editing of stem cell islets for hypoimmunity
    Audrey Parent, University of California San Francisco Diabetes Center, United States
  • 17:30-17:45

    Combinatorial genome engineering strategy for antigen specific protection of stem cell derived beta cells by CAR Tregs
    Jessie Barra, University of Florida College of Medicine, United States
  • 17:45-18:00

    Panel Discussion
  • 18:00-18:05

    Day One Wrap Up
  • 18:05-19:30

    Networking Reception
Tuesday, October 29, 2024
  • 07:00

    Registration opens
  • 07:30-08:45

    Session 6
    Beta Cell Replacement Clinical Trials Update
    Moderator: Jon Odorico
  • 07:30-07:50

    Vertex Trials Update
    Michael Rickels, University of Pennsylvania, United States
  • 07:50-08:10

    CD40L immunosuppression and Sernova Islet transplant trials
    Piotr Witkowski, Transplant Institute University of Chicago Medicine, United States
  • 08:10-08:30

    Parathyroid gland supplemented human islet engraftment and function in humans
    Peter Stock, University of California San Francisco, United States
  • 08:30-08:45

    Panel Discussion
  • 08:45-09:00

    Stretch Break
  • 09:00-10:15

    Session 7
    Immunomodulation/Encapsulation
    Moderator: James Markmann
  • 09:00-09:15

    Overview of Immunomodulation Strategies
    Alessandro Grattoni, Houston Methodist Hospital, United States
  • 09:15-09:30

    Role of EVs in Immunomodulation of stem cell islets
    Edward Phelps, University of Florida, United States
  • 09:30-09:45

    CD40L immunotherapy to protect transplanted islets
    Norma Kenyon, University of Miami Miller School of Medicine, United States
  • 09:45-10:00

    The Good and Bad of Humanized Mouse Models
    Michael Brehm, University of Massachusetts Chan Medical School, United States
  • 10:00-10:15

    Panel Discussion
  • 10:15-10:45

    Coffee Break
  • 10:45-12:00

    Session 8
    Overcoming challenges to broader clinical application of stem cell-derived islets
    Moderator: Esther Latres
  • 10:45-11:00

    Successful cryopreservation of intact stem cell islets
    Joseph Sushil Rao, University of Minnesota, United States
  • 11:00-11:15

    Delivering insulin-producing cells without immunosuppression
    Minglin Ma, Cornell University, United States
  • 11:15-11:30

    Novel scale up technologies
    Kevin Alessandri, TreeFrog Therapeutics, United States
  • 11:30-12:00

    Panel Discussion
  • 12:00-13:00

    Lunch Break & Poster Viewing
  • 13:00-13:30

    Session 9
    Best Abstracts Session III
    Moderator: Michael Rickels
  • Abstract 1

    Sonja Schrepfer
    Hypoimmune Islet Cells Mediate Insulin Independence After Allogeneic Transplantation Without Immunosuppression
  • Abstract 2

    Kfir Molakandov
    IsletRxPlus, CD26− and CD49A+ enriched hESC-derived Islet cells, improves safety and identity profile in diabetic mice at multiple implantation sites.
  • Abstract 3

    Caterra Leavens
    The beta cell “invisibility cloak” – Developing stem cell-derived pancreatic islets that are protected from the immune system
  • Abstract 4

    Mina Seedhom
    Study of interactions between human immune systems and SC-islets from T1D individuals in a novel NSG MHC-DKO Tg(hIL15) mouse
  • 13:30-15:05

    Session 10
    Future Opportunities And Barriers for Broad Clinical Application
  • 13:30-14:15

    Panel 1
    Manufacturing, Scale Up, Regulatory
    Moderator: Jeffrey Millman

    Felicia Pagliuca, Vertex Pharmaceuticals, Inc. United States
    Heather Lombardi, FDA - CBER, United States
    Tom Bollenbach, BiofabUSA, United States

  • 14:20-15:05

    Panel 2
    Eligibility Criteria and Future Clinical Trial Design
    Moderator: Eelco DeKoning

    Lorenzo Piemonti, Universita Vita-Salute San Raffaele, Italy
    Trevor Reichman, U Toronto, Canada
    Marjana Marinac, Breakthrough T1D, United States

  • 15:05-15:10

    Closing


IPTA-VES - International Pediatric Transplant Association Virtual Education Symposium

1st IPTA Virtual Education Symposium - November 14-15

Abstract Submissions are Open!

This symposium is open to all members and trainees of the clinical and academic multi-disciplinary teams in pediatric transplantation.

This interactive symposium is over two half days on Thursday and Friday 14 and 15 November 2024, and commences with two separate streams for medical Fellows and for Allied Health and Nursing professionals.

We hope you will come and join us and look forward to welcoming new IPTA members, and receiving your abstracts.


ISODP Journal Watch - October 2024

For the second edition of 2024’s Journal Watch, the team has uncovered a treasure trove of articles to keep your academic interest stimulated following the TTS Istanbul meeting, where the scientific committee for ISODP Kyoto 2025 also convened.

ISN-TTS Sister Centers Program Application Deadline

The program is a joint partnership between the International Society of Nephrology (ISN) and The Transplantation Society (TTS) to help establish new kidney transplant centers and develop existing kidney transplant programs in emerging countries. Please note that the program is open to all ISN and TTS members.

This initiative fosters partnerships between experienced transplant centers in the developed regions (Supporting Centers or SCs) and new and developing transplant centers (Emerging Centers or ECs) in low-resource regions, providing a framework and funding for up to six years of collaboration if adequate progress is made.

After six- years of improvement on the program, graduated centers are encouraged to support a third center within their region and therefore sustain the impact of their training and help other centers to develop.

Application Deadline
October 15, 2024


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