In Case You Missed It:
TTS Education Committee's Precision Medicine Webinar Series Launch!
The pre-recorded series, applies current perspectives on precision medicine and the role of translational research and scientists/physician’s engagement to the field of transplantation, illustrating how these approaches have led to significant advancements in the field. It provides further justification for deliberate, targeted efforts to cross-in translational transplant research. TTS will release 1 recording per month. TTS members are invited to submit comments and questions about each webinar for two weeks after the video is released on the site. The questions will be sent to the speaker and moderator to respond and we will post the responses. Click Here to view this month’s webinar. Dr. Maarten Naesens presents on System Biology and Precision Transplantation Medicine: The Complexity of the human and transplant model and the different layers of biological information; Current applications; Composite scores: clinical applications. This webinar is moderated by Valeria Mas.
*Note, you must be logged in to participate.CLICK HERE TO VIEW
Transplantation Direct - Highlighted Article
Dr. Peri Husen, Editorial Fellow, Transplantation
Portopulmonary Hypertension: A Survey of Practice Patterns and Provider Attitudes
DuBrock HM, Salgia RJ, Sussman NL, et al.
Transplantation Direct: June 2019 - Volume 5 - Issue 6 - p e456
In this multicenter survey study, DuBrock and coworkers assessed provider attitudes and practice patterns regarding the management of patients with portopulmonary hypertension (POPH) and evaluated the concordance between current guidelines and clinical practice. Survey responses of hepatologists and pulmonary hypertension (PU) physicians at 35 US liver transplant centers were analyzed. The study showed that provider attitudes and practice patterns regarding management of POPH and the role of liver transplantation vary significantly across the country. Overall, this study highlights the need to improve implementation of practice guidelines and standardized care.CLICK HERE TO VIEW (OPEN ACCESS)
Transplantation - WEEK'S MOST DOWNLOADED PAPERCLICK HERE TO VIEW (OPEN ACCESS)
IN THE NEWS
For the First Time in North America, a Woman Gives Birth After Uterus Transplant From a Deceased Donor
July 9 - A baby girl born last month at Cleveland Clinic has made history. She was the first baby in North America delivered by a mother who received a uterus transplant from a deceased donor.
China hospital says baby's kidneys successfully transplanted in woman
July 14 - Doctors in central China's Hubei province said they have successfully transplanted kidneys from a prematurely born donor baby in the body of a 47-year-old woman who was suffering from kidney failure. The donor weighed only 1.3kg, Wuhan Union Hospital said on Wednesday (July 10), calling the baby the lightest kidney donor ever reported.
Two Genes Appear to Act as On/Off Switches for Neuroinflammation and Alzheimer's Disease
July 12 - As the beta-amyloid theory of Alzheimer’s disease fades from prominence, many researchers are turning their attention to the role of inflammation. Although beta-amyloid is still very much a factor in the disease, many believe that it is an uncontrolled or faulty inflammatory and immune reaction to beta-amyloid that causes the majority of the cognitive damage. As a result, many researchers are shifting focus to the role of microglial cells, which are specialized immune cells in the central nervous system, and the potential use of anti-inflammatories in prevention and treatment.
Specific Variables Improve Disease Severity Discrimination Among CF Transplant Candidates
July 15 - The inclusion of Cystic Fibrosis Foundation Patient Registry variables in the lung allocation score (LAS) calculation allowed for enhanced discrimination of disease severity among lung transplant waitlisted candidates with cystic fibrosis (CF), thus providing improved access for those at the highest risk for death. In addition, patients with chronic obstructive pulmonary disease (COPD) also had improved access to transplantation, specifically when forced expiratory volume in 1 second (FEV1) was included as one of the clinical parameters.
New study highlights advantages of living-donor liver transplant over deceased donor
July 12 - Living-donor liver transplant offers numerous advantages over deceased-donor transplant, including better three-year survival rates for patients and lower costs, according to new research from the UPMC Thomas E. Starzl Transplantation Institute and the University of Pittsburgh School of Medicine.
RCC in Advanced CKD: A Transplant Dilemma
July 15 - Non-dialysis patients with advanced CKD diagnosed with renal malignancies grapple with the dual threat of renal failure and cancer progression. When choosing between functional or oncologic risks, many patients will ask about renal transplantation, but discussions of this option are complicated by statistical realities.
Upcoming Meetings and ANNOUNCEMENTS
CTRMS 2019 – Lesvos - Greece
Late Breaking Abstract Submission Deadline is July 29th!
TOND-TDTD - Save the dates - October 10-11, 2019!
The 3rd Joint Meeting of the Turkish Transplantation Society and the Turkic World Transplantation Society will be held in Tashkent, Uzbekistan on October 10-11, 2019. The Scientific and Local Organizing Committees, comprised of international transplantation leaders, have developed a program that reflects current problems and represents a collection of scientific, educational, and practical information. The meeting will be an exciting opportunity for transplant professionals to share their expertise as well as their concerns regarding the development of the field in their own countries.
International Transplantation Science Meeting 2019
ITS 2019 is set for Nov. 10-13 in Clearwater Beach, Florida. Keynote speakers include Katherine High, President and Head of R&D at Spark Therapeutics, and Ronald Germain, chief of Laboratory of Immune System Biology and Lymphocyte Biology Section at the National Institute of Allergy and Infectious Diseases National Institutes of Health.