Just Released! Transplantation Direct - April 2022

The Transplantation Direct line-up for April is online. Among the highlights in this issue include the study of factors influencing kidney transplant survival in older recipients; other studies in kidney transplantation investigate the value of standardizing kidney procurement biopsy procedures, follow-up guidelines to monitor patients being treated for TCMR, and a cautionary case of hepatitis E virus- related immune complex glomerulonephritis. Studies highlighted in liver transplantation look at the effects of phlebotomy during transplant procedures, use of PET/CT myocardial perfusion imaging to risk stratify for cardiovascular morbidity, and the use of pre-transplant checkpoint inhibitors in advanced hepatocellular carcinoma cases. In lung transplantation, predicting lung injury with donor-derived cell-free DNA measurements is explored, and transplantation experiences for pulmonary fibrosis associated with Hermansky-Pudiak syndrome are shared. Papers on parathyroid gland transplantation are also published herein, including the use of near infra-red auto fluorescence imaging to procure glands and, in a child, an experience with simultaneous parathyroid and kidney transplantation in the management of genetic hypothyroidism is detailed. For health care professionals interested in organ donation, we also have a scoping review on understanding the definitions and determination of death. Please visit our Transplantation Direct website for full details, all available in open access.
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Healthcare Professionals’ Understandings of the Definition and Determination of Death: A Scoping Review
Katina Zheng, Stephanie Sutherland, Laura Hornby, Lindsay Wilson, Sam D. Shemie, Aimee J. Sarti

Kidney Transplantation

A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study
Vasiliki Tsarpali, Karsten Midtvedt, Kjersti Lønning, Tomm Bernklev, Anders Åsberg, Haris Fawad, Nanna von der Lippe, Anna Varberg Reisæter, Kjetil Røysland, Kristian Heldal

The Role of Procurement Biopsies in Kidney Acceptance Decision Making and Kidney Discard: Perceptions of Physicians, Nurse Coordinators, and OPO Staff and Directors
Karolina Schantz, Elisa J. Gordon, Unsun Lee, Maria Rocha, John Friedewald, Daniela P. Ladner, Yolanda Becker, Richard Formica, Peter P. Reese, Dixon Kaufman, Masoud Barah, Marissa Walker, Om Mehrotra, Dania Viveros, Sanjay Mehrotra

How Should Acute T-cell Mediated Rejection of Kidney Transplants Be Treated: Importance of Follow-up Biopsy
Fahad Aziz, Sandesh Parajuli, Neetika Garg, Maha Mohamed, Weixiong Zhong, Arjang Djamali, Didier Mandelbrot

An Unusual Cause of Hepatitis With Nephrotic Syndrome in a Kidney Transplant Recipient
Koon Ming Chan, Siddharth Sridhar, Wing Hung Lau, Chi Yuen Cheung

Liver Transplantation

Association of Phlebotomy on Blood Product Transfusion Requirements During Liver Transplantation: An Observational Cohort Study on 1000 Cases
Luc Massicotte, Zoltan Hevesi, Cédrick Zaouter, Lynda Thibeault, Pierre Karakiewicz, Louise Roy, André Roy

The Utility of Noninvasive PET/CT Myocardial Perfusion Imaging in Adult Liver Transplant Candidates
Monica A. Tincopa, Richard L. Weinberg, Shreya Sengupta, Jeremy Slivnick, James Corbett, Christopher J. Sonnenday, Robert J. Fontana, Pratima Sharma

Immune Checkpoint Inhibitor Therapy Before Liver Transplantation—Case and Literature Review
Elizabeth S. Aby, John R. Lake

Lung Transplantation

Clinical Validation of a Plasma Donor-derived Cell-free DNA Assay to Detect Allograft Rejection and Injury in Lung Transplant
Justin P. Rosenheck, David J. Ross, Mena Botros, Alexander Wong, Jonathan Sternberg, Yen-An Chen, Nathan Liang, Amy Baer, Ebad Ahmed, Ryan Swenerton, Bernhard G. Zimmermann, Gordon Fehringer, Zachary P. Demko, Michael Olymbios, Paul R. Billings, Brian C. Keller

Lung Transplantation for Pulmonary Fibrosis Associated With Hermansky-Pudlak Syndrome. A Single-center Experience
Luke Benvenuto, Seema Qayum, Hanyoung Kim, Hilary Robbins, Lori Shah, Angela Dimango, Gabriela Magda, Harpreet Grewal, Philippe Lemaitre, Bryan P. Stanifer, Joshua Sonett, Frank D’Ovidio, Selim M. Arcasoy

Organ Donation and Procurement

Procurement of Deceased Donor Parathyroid Glands With the Aid of Near-infrared Autofluorescence Imaging
Casey J. Ward, Yvonne M. Kelly, Shareef M. Syed, Raphael P.H. Meier, Tadasuke Ando, Steven A. Wisel, James M. Gardner, Peter G. Stock, Quan-Yang Duh

Clinical Method

Simultaneous Kidney and Parathyroidti Transplantaon in the Management of Genetic Hypoparathyroidism in a Child
Natalie Vallant, Manish D. Sinha, Moira Cheung, Nick Ware, Helen Jones, Jackie Buck, Catherine Boffa, Melita Irving, Paul V. Carroll, Johnathan Hubbard, Refik Gökmen, Lesley Rees, Petrut Gogalniceanu, Nicos Kessaris

Transplantation - Highlighted Special Article Collections

​A special collection highlighting the next-generation biomarkers for posttransplantation outcomes. All papers freely available until May 31, 2022!
Read our special Xenotransplantation Research collection, proving the latest insights on this rapidly developing field.

Transplantation - Week's Most Downloaded Paper

#TBT o this week's featured top downloaded paper from 2019-20: Impact of Tocilizumab (Anti-IL-6R) Treatment on lmmunoglobulins and Anti-HLA Antibodies in Kidney Transplant Patients With Chronic Antibody-mediated Rejection

Transplantation Direct - Week's Most Downloaded Paper

This association suggests that GER may cause an immune response to normally sequestered lung-associated self-antigens that drives ongoing lung injury. #OpenAccess #TransplantTwitter

TTS 2022 - Program overview with speakers is available

Take a few minutes to look over our program to start planning your trip to Argentina!

April 20 Critical Path Institute Webinar

New program to attract medical students to pursue a career in the field of transplantation

In order to encourage the next generation of medical doctors to pursue a career in the field of transplantation, we are looking for medical students interested in participating in The Transplantation Society (TTS) 2022 Congress in Buenos Aires, Argentina being held on September 11th-14th. Selected medical students will participate in three workshops by asking questions to the panelists. Additionally, students will attend five other sessions of their choice, and special events, and will participate in TTS 2022 social media activity. Students will be mentored to develop a slide deck presentation with highlights of the sessions attended. Their experience at the Congress, as well as key take-home messages, will be shared with their medical school peers. Their slide decks and other materials from the congress will be featured on the TTS website.

TTS Call for Award Nominations - Deadline May 1

Spotlight on The TTS Recognition Awards

Call for nominations

These awards recognize individuals who have made a major international impact in the field of transplantation. The awards are given out at each International Congress of The Transplantation Society and carry a monetary award of USD $2,000 each.
  • Outstanding Achievement Transplantation Science (Basic)
  • Outstanding Achievement in Transplantation Science (Clinical)
  • Outstanding Achievement in Transplantation Science (Developing Country)
  • Mentorship or Education and Training in Transplantation

The Medawar Prize

The Medawar Prize, , named after Society co-founder Sir Peter Medawar, is recognized as the world's highest dedicated award for the most outstanding contributions in the field of transplantation. The Medawar Prize has been awarded at each of our Society's biennial Congresses since 1990.

The award recognizes the outstanding investigators whose contributions have had such a profound influence on the field of organ transplantation. The Medawar Prize is universally considered to be commensurate with the most outstanding world prizes for scientific achievement.

Thomas Starzl
Innovation Award

The TTS Starzl Innovation Award is named after Tom Starzl who was best known for his contributions to the field of organ transplantation, and often referred to as the “father of transplantation”. The award recognizes individuals who, though advanced and original work, have contributed significantly to transplantation, thereby reflecting the spirit pioneered by Dr. Starzl. This award is supported by Başkent University.

WIT Awards

The Women in Transplantation Steering Committee have created the Woman Leader in Transplantation Award to recognize a woman who has helped further the field of transplantation through research, policies, leadership, initiatives or other regarded contributions. The Unsung Hero Award will be presented to one woman who has had an extraordinary impact in transplantation through community service, volunteering, mentorship or other community based activity. Both Awards are presented during the presidential address at the TTS International Congress.

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WIT Awards

The Women in Transplantation Steering Committee have created the Woman Leader in Transplantation Award to recognize a woman who has helped further the field of transplantation through research, policies, leadership, initiatives or other regarded contributions. The Unsung Hero Award will be presented to one woman who has had an extraordinary impact in transplantation through community service, volunteering, mentorship or other community based activity. Both Awards are presented during the presidential address at the TTS International Congress.


TTS 2022 Elections are ongoing until May 11, 2022. Vote today!

Voting is an important responsibility and privilege for all our members and by taking a moment to vote you will help shape our leadership and our future!

NEW! TTS Research Grants Program

TTS will provide funding to three individual investigators to support their research in transplantation. The spectrum of studies includes basic, clinical/epidemiological and translational. This individual should have spent five years or less performing research in transplantation (and/or immunology relating to transplant) since obtaining their last doctoral degree (PhD, MD, PharmD, or equivalent). One of these research grants will be preferentially designated to TTS members from a low- or middle-income country.
General Information
  1. The three seeding grants, at $25,000 each, will provide support to clinical, basic and translational scientists working within the field of transplantation. Research must commence on September 1st 2022 and conclude on 31st October, 20, 2024.

  2. Up to $25k per year for up to 2 years with requirement for annual reporting. The extra 2 months is intended to provide buffer for start-up, i.e. 14 months first period and 12 months second period

  3. The research start date cannot be deferred for any reason.

  4. Applications must be submitted in full by June 1st 2022 in order to be reviewed.

  5. The recipient will sign a letter of agreement with TTS. Payments will be issued to the recipient’s institution by TTS, and the recipient will report to the TTS Research Grant Committee.
Research Focus
The 2022 TTS Research Grant will fund research that encompasses epidemiologic, clinical, translational, and basic studies as well as studies to expand access to transplantation, including, but not limited to: Improving global access to transplantation and outcomes of transplantation.

About our TTS Ukraine Fund and TTS Matching of Donations

Statement of The Transplantation Society’s support to the people of Ukraine.

As the global leader in transplantation, committed to health and life for all, The Transplantation Society expresses grave concern over the escalating violence and humanitarian crisis in Ukraine.

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The protection of civilians and preservation of healthcare is imperative. TTS stands ready to support our colleagues, friends, families and patients impacted by this tragedy. As a non-State actor in official relations with the World Health Organization, we will seek collaborate with the WHO to provide our expert assistance on the Ukraine emergency

We are monitoring the situation and have setup a donation page (https://ukraine.tts.org) to collect funds to be distributed to support the maintenance of healthcare in the Ukraine and assist transplant patients as may be possible. We will also reach out to contacts to assess how we can assist to re-establish transplantation activities once the crisis has ended. TTS will match each contribution, dollar for dollar, up to $50,000 USD in total.

Individuals may also contribute to the WHO foundation directly using this link:

Women in Transplantation @ ISHLT 2022 Congress

Dr. Hannah Valantine
Dr. Lori West

Registration Deadline: Friday, April 22.

Women in Transplantation (WIT) are delighted to announce their FIRST LIVE IN-PERSON NETWORKING EVENT IN 2 YEARS!

To launch what we hope will be a series of in-person networking events around the globe in 2022, WIT is pleased to announce that Dr. Hannah Valantine will give a presentation as part of this session.

This event will take place on Tuesday 26th April at 5.30pm EDT at the 42nd Annual Meeting of the International Society for Heart and Lung Transplantation (ISHLT) as a pre-Congress Networking event.

ISHLT’s meeting will be held at the John B. Hynes Memorial Convention Center in Boston, USA from Wednesday 27 April to Saturday 30 April 2022.

WIT members who are registered for and attending ISHLT will receive complimentary registration for the Networking session. Please follow this link to register: www.surveymonkey.com/r/6YTXBW8

We look forward to welcoming you back!

Please note that access to the WIT Networking event is only open to those registered for the ISHLT meeting. Drinks and light refreshments will be served.

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