Optimizing Mycophenolic Acid Exposure in Kidney Transplant Recipients: Time for Target Concentration Intervention #TBT
In this review, the totality of evidence supporting mycophenolate CCD is examined: pharmacological characteristics, observational data linking exposure to efficacy and toxicities, and randomized controlled trials of CCD, with attention to dose optimization method and exposure achieved.A Comorbidity Index and Pretransplant Physical Status Predict Survival in Older Kidney Transplant Recipients: A National Prospective Study#OpenAccess #TransplantTwitter
Kidney transplantation (KT) is considered the best treatment for end-stage kidney disease (ESKD). In the increasing elderly ESKD population, KT should be reserved for carefully selected candidates who are expected to experience favorable outcomes. We aimed to prospectively evaluate pretransplant recipient factors that may predict patient survival and can eventually guide therapeutic decisions in elderly with ESKD.We are excited to be able to celebrate Howard. Throughout his 43+ year career, Howard’s visionary efforts to move the field of organ and tissue donation forward have resulted in the successful coordination of more than 55,000 life-saving organs for transplant and more than 2 million life enhancing tissues for transplant through Gift of Life Donor Program alone. Each precious gift offered hope to patients and their families. His tireless dedication, leadership, and mentorship have influenced best donation practices and policies regionally, across the United States and around the world.
Many professionals in our chosen field have had the chance to work with Howard throughout his career and have experienced first-hand his dedication and commitment. His passion to advance the Art & Science of Donation is well established, with Gift of Life Institute supporting innovation and accountability in the field. And it is only because of Howard’s compassion and commitment to the families undergoing the challenging transplant journey that his dream of Gift of Life Family House became a reality, a home away from home for transplant families travelling to the Philadelphia region for their transplant care. Informed by his own family’s experience while his sister underwent her life saving liver transplant, Howard took action to complete the circle of care provided by the Gift of Life family.
The Family House, celebrating its 10 years of providing support and affordable lodging stands as a testament to what Howard sought for all families. Compassion, care and expertise all harnessed to support life-saving work grounded in the altruistic acts of donor families.
We are all grateful for Howard’s leadership, his vision, his tenacity, and his personal compassion. We hope you will join us in this singular opportunity to thank an exceptional man who has had a foundational impact on the profound work we all share.
Sincerely,
Richard Hasz
President and CEO, Gift of Life Donor Program
215-557-8090 | rhasz@donors1.org
Human organ and tissue transplantation will be on the agenda for the upcoming "Seventy-fifth World Health Assembly" being held from May 22-28. In advance of the assembly the Director-General issued a PDF report which may be downloaded below. TTS will make a statement addressed to the Assembly commenting on the report, endorsing WHO action and encouraging member states to continue to invest in transplantation.
IPTA is delighted to announce that the recordings from the 11th IPTA Congress are now available for viewing for IPTA and TTS members on the IPTA website. Don’t miss the opportunity to learn from this rich educational content.
As the global leader in transplantation, committed to health and life for all, The Transplantation Society expresses grave concern over the escalating violence and humanitarian crisis in Ukraine.
The protection of civilians and preservation of healthcare is imperative. TTS stands ready to support our colleagues, friends, families and patients impacted by this tragedy. As a non-State actor in official relations with the World Health Organization, we will seek collaborate with the WHO to provide our expert assistance on the Ukraine emergency
We are monitoring the situation and have setup a donation page (https://ukraine.tts.org) to collect funds to be distributed to support the maintenance of healthcare in the Ukraine and assist transplant patients as may be possible. We will also reach out to contacts to assess how we can assist to re-establish transplantation activities once the crisis has ended. TTS will match each contribution, dollar for dollar, up to $50,000 USD in total.
The Transplantation Society
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